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| Total Records: 131 |
|
Last Name |
First Name |
Research/Clinical Interest Title |
Keywords |
| RICHTER |
JILLIAN |
Endothelial Glycocalyx as a Mechanoregulator of Post-Traumatic Lung Injury |
trauma, hemorrhage, resuscitation, vascular biology, organ failure, blood transfusion, plasma, whole blood, platelets, endothelial glycocalyx layer, lung injury, bioengineered in vitro models, mechanotransduction |
| ROBERSON |
ERIK |
Neurobiology of Alzheimer's Disease and Frontotemporal Dementia |
Neurodegeneration, Alzheimer's disease, frontotemporal dementia, tau, progranulin, excitability, signaling, plasticity, behavior |
| ROWE |
GLENN |
Exercise-Induced Metabolic Adaptations in Striated Muscle |
striated muscle, mitochondria, transcriptional regulation, metabolism, exercise |
| SAMANT |
RAJEEV |
Tumor progression and metastasis of cancer. |
Epithelial-Mesenchymal-Transition, mylti-protein complexes, transcription regulation, nucleolus, protein stability, chaperones, Hest shock proteins |
| SANDERS |
PAUL |
Mechanisms of Disease Progression in the Kidney |
salt-sensitive hypertension, transforming growth factor-ß, nitric oxide, hypertensive nephrosclerosis, monoclonal immunoglobulin light-chain-related renal diseases |
| SANDERSON |
RALPH |
Molecular Regulation of the Tumor Microenvironment |
tumor, microenvironment, cancer, heparan sulfate, proteoglycan, heparanase, exosomes, metastasis, bone, myeloma, breast cancer, drug resistance |
| SCHWIEBERT |
LISA |
Airway inflammation; lung function; asthma and exercise |
|
| SERRA |
ROSA |
Mechanism of TGF-ß Action in Developmental and Disease Processes |
developmental biology, bone, cartilage, teeth, intervertebral disc, osteoarthrits, skeletal disease |
| SHACKA |
JOHN |
Targeting the Autophagy-Lysosome Pathway for Therapeutic Benefit in Parkinson's Disease |
Autophagy; Lysosome; Parkinson's; Synuclein; Alpha-Galactosidase |
| SHEVDE-SAMANT |
LALITA |
Investigating molecular signaling mechanisms that present as fundamental aberrations in tumor cells or their immune microenvironment |
Tumor progression, metastasis, innate and adaptive immune microenvironment, signaling, cancer stem cells, chemoresistance, metabolism, osteolysis, Merlin, Hedgehog pathway, Wnt pathway |
| SMITH |
PETER |
The role of the membrane cytoskeleton in regulating the cell surface expression of epithelial transport proteins. |
|
| SONG |
YUHUA |
An integrated multi-scale computational modeling and biological experimental research program to study apoptosis, cell adhesion and biomaterial design |
Computational Biology/Biomechanics, Mechanotransduction, Protein/Biomembrane structure and function, death receptor-mediated apoptosis, Cell adhesion, Biomaterials |
| SONTHEIMER |
HARALD |
The Role of Neuroglia in Brain Function and Disease |
Cell migration, brain development, primary brain tumors, glioma, astrocytes, oligodendrocytes, stem cells, regeneration |
| STANDAERT |
DAVID |
Translational Research in Neurodegenerative Diseases |
Parkinsons Disease, Dystonia, Movement Disorders |
| VAN GROEN |
THOMAS |
Treatment of Alzheimer's disease with small abeta-oligomer binding peptides |
Alzheimer's disease, pathology, amyloid beta, peptides, cognition, behavioral assessment |
| VAN WAARDENBURG |
ROBERT |
Structure-Function analysis of Tyrosyl-DNA phosphodieasterase I; Developing a DNA Repair Enzyme as Therapeutic Target for Anti-Cancer Treatment |
Structure-function analysis, Mechanism of Action of proteins and drugs (chemotherapeutics), Drug Development for novel therapeutic targets, Post-translational modification by Ubiquitin and SUMO (Small Ubiqitin like modifier), Protein interactions |
| VOLPICELLI-DALEY |
LAURA |
Cognitive impairments in Parkinson's disease and Lewy body dementias |
Parkinson's disease, Lewy body dementias, synuclein, tau, glucocerebrosidase, cell biology of the neuron, neurodegeneration |
| WANG |
JIANBO |
The Planar Cell Polarity Pathway in mammalian embryogenesis |
mouse genetics, morphogenesis, cell polarity |
| WANG |
QIN |
neurosynaptic signaling in neurological and psychiatric diseases |
synaptic receptors, signaling, protein trafficking, ligand regulation, neurodegeneration, neuroprotection, Alzheimer's disease, cognition, mood disorders |
| WENDE |
ADAM |
Glucose-mediated remodeling of cardiac DNA methylation |
Diabetes, Hypertension, Exercise, Mitochondria, Metabolism, Glucose, Epigenetics, Gene expression, transcription, O-GlcNAc, protein modifications, DNA methylation, Histone modification, GLUT4, PDK2, PDK4 |
| WHITE |
CHARLES |
|
|
| YACOUBIAN |
TALENE |
Role of 14-3-3 proteins in Parkinson’s disease |
Parkinsons disease; Neurobiology; Molecular Genetics & Disease |
| YANG |
EDDY |
Targeting DNA repair pathways to augment the therapeutic ratio for cancer patients |
nanostring, profiling, DNA damage, DNA repair, EGFR, cancer, PARP, apoptosis, brain, protection, GSK3 |
| YANG |
YANG |
Multiple myeloma and tumor microenvironment |
Tumor microenvironment, cancer-related bone diseases, multiple myeloma, Runx2, syndecan-1, heparanase |
| YODER |
BRADLEY |
Cilia Signaling and Dysfunction in Development and Disease |
Cilia, cystic kidney diseases, obesity, signal transduction, cell fate determination and embryonic patterning, birth defects, mouse and C. elegans models. |
| YUSUF |
NABIHA |
Innate immune mechanisms in tumor development |
toll like receptors, type I interferons, immune system, cancer, T-cells |
| ZAJAC |
ALLAN |
Anti-Viral Immunity; T Cell Responses; Immunological Memory |
Immunology, Virology, Pathogenesis, Vaccines, T cells |
| ZAYZAFOON |
MAJD |
The Role of Calcium Signaling in the pathogenesis of disease |
Osteoblasts, Bone, Prostate Cancer, Osteosarcoma, Calmodulin Kinase, NFAT, AP-1, Bone metastasis, HDAC, histone acetylation, DNA methyltransferase |
| ZHANG |
JIANHUA |
Mechanisms and regulation of autophagy-lysosomal pathway in health and diseases |
Autophagy, Parkinson's Disease, Alzheimer's disease, heart disease, lysosomes, mitochondria, redox signaling |
| ZHENG |
X. LONG |
Molecular Mechanisms of Normal and Abnormal Blood Clotting; Inflammation and Microvascular Thrombosis; CRISPR/Cas9 Gene Editing as a Novel Therapeutic Strategy for Thrombotic Diseases |
ADAMTS13, von Willebrand factor, TTP, Arterial thrombosis, Vascular biology, Autoimmunity, and Inflammation, CRISPR/Cas9 Gene Editing |
| ZHOU |
LUFANG |
Mitochondrial dysfunction and oxidative stress in human disease |
mitochondrial biology, cardiovascular disease, multiscale computational modeling, live cell imaging, optogenetics |
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