Pathobiology and Molecular Medicine  http://www.gbs.uab.edu  http://www.uab.edu/graduate  Back to Main
 Faculty Listing
Total Records: 131
Last Name First Name Research/Clinical Interest Title Keywords
WHITE CHARLES
ABSHER DEVIN
FANUCCHI MICHELLE
QIN HONGWEI
PREUSS MEREDITH
LIU RUI-MING Oxidative stress, Aging, Lung fibrosis, Alzheimer's disease
ELTOUM ISAM-ELDIN - Clinical research in diagnostic cytology and surgical pathology- Tumorogenesis of prostate cancer and chemoprevetion - HPV infection EUS-FNA, Prostate cancer in transgenic animals, HPV infection, Cytology, Immunopathology
FULLER CATHERINE ENaC/ASIC Ion Channels; Sodium channels, glioma, migration, proliferation, cancer, signaling, polycystic kidney disease
KING PETER 1) RNA Regulation of Inflammation in ALS and other Neurodegenerative Disorders, 2) Smads as Biomarkers of ALS Disease Progressionh RNA stability; AU-rich elements; cytokines and chemokines; glioblastoma; amyotrophic lateral sclerosis, stroke, spinal cord injury, HuR, KSRP
NAHM MOON Adaptive and Innate Immune Responses to Pneumococci and Pneumonia Vaccines pneumococcus, capsule, innate immunity, pathogenesis, vaccines
SCHWIEBERT LISA Airway inflammation; lung function; asthma and exercise
SONG YUHUA An integrated multi-scale computational modeling and biological experimental research program to study apoptosis, cell adhesion and biomaterial design Computational Biology/Biomechanics, Mechanotransduction, Protein/Biomembrane structure and function, death receptor-mediated apoptosis, Cell adhesion, Biomaterials
PARANT JOHN Animal Models of Genomic Instability, p53 Regulation, Cancer and Mitotic Dysfunction Zebrafish, Mouse, Li Fraumeni Syndrome, Roberts syndrome, Birth Defects, Tumor Suppressor, Genomic Instability, Aneuploidy, Mitosis, DNA damage, Cancer, and Apoptosis.
PLACZEK WILLIAM Anti-cancer target validation and structure-based drug discovery. NMR spectroscopy, cancer, drug discovery, peptide synthesis, structural biology, apoptosis, signaling
ZAJAC ALLAN Anti-Viral Immunity; T Cell Responses; Immunological Memory Immunology, Virology, Pathogenesis, Vaccines, T cells
MOUNTZ JOHN autoimmunity, immune senescence, gene therapy type I IFNs, IL-23, germinal centers, marginal zone macrophages, inflammatory macrophages, rheumatoid arthritis, lupus
GRAY MICHAEL Bacterial responses to oxidative stress microbiota, redox, stress, probiotics, reactive chlorine, inflammation
PENG JI-BIN Calcium transport proteins and their roles in health and disease Calcium transport, absorption, reabsorption, hyercalciuria, hypertension, TRPV6, TRPV5, WNK4
BUCHSBAUM DONALD Cancer immunotherapy Immunotherapy, Wnt inhibitors, pancreatic cancer, breast cancer, ovarian cancer
LEAVENWORTH JIANMEI Cancer-Immune cell Crosstalk: Discovery of new targets for cancer immunotherapy Immunology, Cancer Immunology, Immunotherapy, Treg, NK cells, glioma
CHATHAM JOHN Cardiomyocyte function and survival in ischemia/reperfusion and the impact of diabetes: Myocardial ischemia, diabetic cardiomyopathy, O-GlcNAc, STIM1, Ca2+-signaling
ANDERSON PETER Cardiovascular Pathophysiology and Health Sciences Education Cardiovascular pathology, animal models of human disease, technology enhanced education
CHAUDRY IRSHAD Cardiovascular/Immunological Alterations Following Trauma-Sepsis trauma, hemorrhage, sepsis, gender dimorphism, immune functions, cardiovascular functions
CRON RANDALL CD4 T Lymphocyte Transcriptional Regulation Lupus, HIV-1, CD4 T Cell, Transcription, Nuclear Factor of Activated T Cells, Macrophage Activation Syndrome, Temporomandibular Joint (TMJ)
BEVENSEE MARK Cellular and Molecular Physiology of Acid-base Transporters and pH Regulation acid-base, bicarbonate, transporter, brain, fluorescence dyes, glia , heart, intracellular pH, microelectrodes, neuron, Xenopus oocyte, neuronal firing, kidney, polycystic kidney disease, epithelial sodium channel
HABLITZ JOHN Cellular Mechanisms of Neurotransmission
COWELL RITA Cellular Vulnerability in Development and Aging: Using the Molecular Phenotype of Neurons to Elucidate Mechanisms of Disease and Identify Targets for Intervention Transcription, Parkinson Disease, Huntington Disease, schizophrenia, movement disorders, GABA, Neuroanatomy, Metabolism, Mitochondria, Neurobiology, Mouse models
YODER BRADLEY Cilia Signaling and Dysfunction in Development and Disease Cilia, cystic kidney diseases, obesity, signal transduction, cell fate determination and embryonic patterning, birth defects, mouse and C. elegans models.
VOLPICELLI-DALEY LAURA Cognitive impairments in Parkinson's disease and Lewy body dementias Parkinson's disease, Lewy body dementias, synuclein, tau, glucocerebrosidase, cell biology of the neuron, neurodegeneration
BASU MALAY Computational Genomics and Bioinformatics Genomics, bioinformatics, high-performance computing, grid computing, computational biology, evolution
KIM JEONGA Cross-talk between inflammation and insulin signaling Insulin Resistance, Endothelial Dysfunction, NO, ROS, Polyphenol
GOEPFERT PAUL Determining the mechanisms allowing T cells to control HIV replication in vivo
RICHTER JILLIAN Endothelial Glycocalyx as a Mechanoregulator of Post-Traumatic Lung Injury trauma, hemorrhage, resuscitation, vascular biology, organ failure, blood transfusion, plasma, whole blood, platelets, endothelial glycocalyx layer, lung injury, bioengineered in vitro models, mechanotransduction
BALLINGER SCOTT Environmental cardiology, free radical biology, mitochondrial function, mitochondrial - nuclear interactions mitochondria, oxidative stress, evolutionary medicine, cardiovascular disease, cancer, metabolism
LU RUI Epigenetic Mechanisms in Cancer Initiation, Maintenance, and Drug Resistance Cancer, Leukemia, Epigenetics, Genomics, Chromatin, Gene regulation, Novel therapeutics
BALKOVETZ DANIEL Epithelial Cell Biology; Epithelial Cell Signal Regulation; Regulation of paracellular transport across epithelial cell tight junctions epithelial cells, claudins, tight junctions, E-cadherin, hepatocyte growth factor, ERK, MDCK
BAMMAN MARCAS Exercise as a discovery tool and treatment in regenerative medicine and medical rehabilitation. exercise medicine, medical rehabilitation, regenerative medicine, clinical trial, muscle biology
ROWE GLENN Exercise-Induced Metabolic Adaptations in Striated Muscle striated muscle, mitochondria, transcriptional regulation, metabolism, exercise
PONNAZHAGAN SELVARANGAN Experimental Cancer Therapeutics and BOne Diseases: From Basic to Preclinical Studies Breast Cancer; Prostate Cancer; Osteoimmunology; Bone Metastasis; Osteogenesis; Bone Fracture; Stem Cell Therapy
HARTMAN JOHN Experimental models of gene interaction networks that buffer human disease using cell array phenotyping of yeast gene knockout libraries yeast genetics, quantitative high throughput cell array phenotyping (Q-HTCP), gene interaction networks, cellular quiescence and aging, cystic fibrosis, systems biology, drug discovery, lab automation
MITRA KASTURI Exploring the significance of mitochondrial structural change in health and disease Mitochondria, Cell proliferation, Energetics, Cancer, Stem cells
MURPHY-ULLRICH JOANNE Extracellular Matrix Control of Cell and Growth Factor Function, multiple myeloma, diabetic complications, glaucoma atherosclerosis, diabetic complications, tumor microenvironment, multiple myeloma, osteolytic bone disease, glaucoma, fibrosis, TGF-beta, thrombospondin
HABEGGER KIRK FGF21 as mediator of the metabolic actions of glucagon & Duodenal nutrient exclusion enhances glucose metabolism via CNS regulation
CHEN YABING Gene Regulation and Function in the Pathogenesis of Cardiovascular Disease and Aging vascular smooth muscle cells, excellular matrix, vascular calcification, atherosclerosis, diabetes, aging
FERNANDEZ JOSE Genetic basis for racial/ethnic differences in obesity and metabolic outcomes obesity, nutriton, genetics, genetic admixture, racial disparities
BRIDGES STANLEY Genetic influences on susceptibility, severity, and treatment response in rheumatoid arthritis Rheumatoid arthritis; genetics; African-Americans; pharmacogenetics; biomarkers; autoantibodies
EDBERG JEFFREY Genetic Polymorphisms in Wegener’s Granulomatosis
WENDE ADAM Glucose-mediated remodeling of cardiac DNA methylation Diabetes, Hypertension, Exercise, Mitochondria, Metabolism, Glucose, Epigenetics, Gene expression, transcription, O-GlcNAc, protein modifications, DNA methylation, Histone modification, GLUT4, PDK2, PDK4
FRANK STUART Growth Hormone Action and GH Receptor Structure and Function growth hormone, signaling, prolactin, IGF-1, growth factors
POLLOCK DAVID Hypertension and Renal Disease hypertension, diabetes, sickle cell, hemodynamics, endothelin, nitric oxide, kidney, sodium
BHATNAGAR SUSHANT Identification and characterization of novel factors in insulin secretion in obesity and type 2 diabetes Obesity, Type 2 Diabetes, Beta Cell Biology, Insulin Secretion, SNARE Biology, Secreted Proteins, Insulin Granule Trafficking, Tomosyn Proteins, Post-translational Modifications
GEORGE JAMES Immune regulation of post-transplant vascular disease and allograft rejection Transplantation, Heme oxygenase, Stress, Vascular disease, Heart disease, Nephrology
HEL ZDENEK Immunology and pathogenesis of HIV-1 / AIDS; Neutrophil biology; Effect of hormonal contraception on immune system; Design of novel strategies for immunotherapy of cancer. Immunology, Neutrophils, HIV-1, Vaccine, Cancer.
KANO SHINICHI Immunology of brain homeostasis and disease Neuroimmunology, Glia, Cytokine, Epigenetics, Extracellular vesicles, Schizophrenia
LEAL SIXTO Infectious Disease Diagnostics, Drug Discovery, and Effector Functions of Phagocytic Cells Clinical Microbiology, Medical Microbiology, Molecular Diagnostics, Microbiology, Neutrophils, PMNs, fungi, mold, mollicutes
YUSUF NABIHA Innate immune mechanisms in tumor development toll like receptors, type I interferons, immune system, cancer, T-cells
MESSINA JOSEPH Insulin and Growth Hormone (GH) Action, Insulin and GH Resistance Following Injury/Trauma, Infection and Polytrauma Insulin Resistance, Growth Hormone Resistance, Signal Transduction, Gene Expression, Stress, Injury, Trauma, Infection, Polytrauma
OJESINA AKINYEMI Interplay of Genomic Alterations and Microbial Influences in Cancer cancer, infection, genomics, transcriptome, HIV, HPV, EBV, cervical, lymphoma, early detection, recurrence, precancerous, progression, mutations, microbiome, viral, RNASeq, diagnostics, therapy, global health, molecular epidemiology, women's health
MAYNARD CRAIG Intestinal Immune Regulation in Health and Disease immunoregulation, microbiota, inflammatory bowel disease (IBD)
SHEVDE-SAMANT LALITA Investigating molecular signaling mechanisms that present as fundamental aberrations in tumor cells or their immune microenvironment Tumor progression, metastasis, innate and adaptive immune microenvironment, signaling, cancer stem cells, chemoresistance, metabolism, osteolysis, Merlin, Hedgehog pathway, Wnt pathway
LI YI-PING Investigating the mechanisms of skeletal and craniofacial development, tumorigenesis and cancer metastasis; as well as developing effective new therapies for the treatment and prevention of related diseases. Osteoclasts, Osteoblasts, Bone formation and bone resorption, Skeletal development, Tumorigenesis, Cancer bone metastasis, Muscular development, Brain and craniofacial development, Skeleto-muscular disease, and Anti-cancer drug discovery
SERRA ROSA Mechanism of TGF-ß Action in Developmental and Disease Processes developmental biology, bone, cartilage, teeth, intervertebral disc, osteoarthrits, skeletal disease
ZHANG JIANHUA Mechanisms and regulation of autophagy-lysosomal pathway in health and diseases Autophagy, Parkinson's Disease, Alzheimer's disease, heart disease, lysosomes, mitochondria, redox signaling
PRABHU SUMANTH Mechanisms of cardiac remodeling and repair in heart failure heart failure, ventricular remodeling, stem cells, inflammation, cardiac function
SANDERS PAUL Mechanisms of Disease Progression in the Kidney salt-sensitive hypertension, transforming growth factor-ß, nitric oxide, hypertensive nephrosclerosis, monoclonal immunoglobulin light-chain-related renal diseases
BARNES JARROD Mechanisms of metabolic dysregulation and aberrant glycosylation in pulmonary disease glycosylation, pulmonary vascular disease, metabolism
ZHOU LUFANG Mitochondrial dysfunction and oxidative stress in human disease mitochondrial biology, cardiovascular disease, multiscale computational modeling, live cell imaging, optogenetics
DARLEY-USMAR VICTOR Mitochondrial Health; Bench to Bedside mitochondria, nitric oxide, reactive oxygen species, bioenergetic dysfunciton, translational research
PATEL RAKESH Modulation of Inflammation by Reactive Species and N-glycans vascular, hemoglobin, red cells, Inflammation, isoflavones, Nitric oxide, nitrite, N-glycan, matrikine
GARVEY W. Molecular and physiological pathogenesis of human insulin resistance Insulin resistance, obesity, Metabolic Syndrome, Type 2 Diabetes
BEBOK ZSUZSANNA Molecular mechanisms by which cellular stress responses such as the unfolded protein response (UPR) contribute to the pathology of human disorders. membrane proteins, ER stress, UPR, SNP, mutation, CFTR, micro-RNA
HURST DOUGLAS Molecular mechanisms of cancer metastasis metastasis, breast cancer, chromatin modification, microenvironment, tumor progression
BAILEY SHANNON Molecular mechanisms of chronic alcohol and obesity induced fatty liver disease Molecular mechanisms of alcohol and obesity induced liver diseases; Mitochondrial dysfunction in disease; Molecular bioenergetics; Circadian biology; Functional proteomics; Nitric oxide; Free radical biology; Toxicology
ZHENG X. LONG Molecular Mechanisms of Normal and Abnormal Blood Clotting; Inflammation and Microvascular Thrombosis; CRISPR/Cas9 Gene Editing as a Novel Therapeutic Strategy for Thrombotic Diseases ADAMTS13, von Willebrand factor, TTP, Arterial thrombosis, Vascular biology, Autoimmunity, and Inflammation, CRISPR/Cas9 Gene Editing
DING QIANG Molecular mechanisms of organ fibrosis Signal Transduction; Cell Physiology, Adhesion & Migration Signaling; Molecular Genetics & Disease; Gene Regulation and Expression
SANDERSON RALPH Molecular Regulation of the Tumor Microenvironment tumor, microenvironment, cancer, heparan sulfate, proteoglycan, heparanase, exosomes, metastasis, bone, myeloma, breast cancer, drug resistance
DETLOFF PETER Mouse Models of Human Genetic Disorders
LORENZ ROBINNA Mucosal Immunology gastritis, helicobacter, inflammatory bowel disease, mucosal immunology, asthma, diabetes
YANG YANG Multiple myeloma and tumor microenvironment Tumor microenvironment, cancer-related bone diseases, multiple myeloma, Runx2, syndecan-1, heparanase
ROBERSON ERIK Neurobiology of Alzheimer's Disease and Frontotemporal Dementia Neurodegeneration, Alzheimer's disease, frontotemporal dementia, tau, progranulin, excitability, signaling, plasticity, behavior
GALIN F. Neuroimmunology/Multiple Sclerosis
WANG QIN neurosynaptic signaling in neurological and psychiatric diseases synaptic receptors, signaling, protein trafficking, ligand regulation, neurodegeneration, neuroprotection, Alzheimer's disease, cognition, mood disorders
HYNDMAN KELLY Novel mechanisms of HDAC1 regulation of collecting duct function. nitric oxide, endothelin, collecting duct, histone deacetylase, Aquaporin-2
DEVILLIERS PATRICIA Novel Target for Head and Neck Cancer: The Sonic Hedgehog Pathway ameloblastoma, sonic hedgehog, odontogenic tumors, head and neck pathology,
CHENG GUANGJIE Nox- and heme peroxidase-mediated cell signaling and inflammatory diseases Reactive oxygen species, Nox enzymes, Heme peroxidases, Cell signaling, Cardiovascular, Inflammation
KNIGHT JOHN Oxalate Handling and Synthesis and its Relationship to Health and Disease Calcium oxalate kidney stone disease, Oxalobacter formigenes, primary hyperoxaluria
HOLMES ROSS Oxalate Handling and Synthesis and its Relationship to Health and Disease urolithiasis, oxalate, glycolate, hydroxyproline, metabolism
BANERJEE RONADIP Pancreatic Beta-Cell Biology; Molecular mechanisms of beta-cell adaptation during pregnancy and dysregulation in gestational diabetes diabetes mellitus, prolactin receptor, beta-cell biology, pregnancy, transcriptional regulation
GRAY MICHELLE Pathogenesis of Huntington's Disease Huntington's disease, neurodegeneration, neuroscience, astrocytes
LIMDI NITA Pharmacogenomics research and Implementation Science Personalized Medicine, Precision Medicine, Pharmacogenomics, Implemental Science, Pharmacoepidemiology, Pharmacoeconomics, Warfarin , Antiplatelet drugs, Antithrombotic, comparative effectiveness
KRAFT TIMOTHY Physiology and Pathophysiology of Photoreceptors
INSCHO EDWARD Physiology and pathophysiology of the renal microcirculation microcirculation, afferent arterioles, autoregulation, inflammation, purinoceptors, endothelin, renal injury, Toll-like receptor 4 (TLR4)
HARRINGTON LAURIE Protective and Pathogenic CD4 T Cell Responses CD4 T cells, autoimmunity, immunological memory, cytokines
KIM HELEN Proteomics of neuroprotective and chemopreventive actions of dietary phytochemicals neuroprotection, proteomics, protein modifications, antioxidant dietary supplements, menopause, neurogenesis
BLALOCK JAMES Rational Drug and Vaccine Design/Neutrophilic Inflammation
DICKINSON DALE Redox cell signaling and environmental exposures; natural products and chemoprevention glutathione; redox; Nrf2; antioxidant; microRNA; nutraceutical
AGARWAL ANUPAM Regulation of heme oxygenase gene expression in kidney and vascular injury heme oxygenase, acute kidney injury, transplant nephrology, transcriptional gene regulation
BULLARD DANIEL Regulation of Immune and Inflammatory Responses adhesion molecules, lupus, vasculitis, psoriasis
MCNICHOLAS-BEVENSEE CARMEL Regulation of ion channels Ion channel, Pulmonary, Cardiovascular, Sweat gland
ELSON CHARLES Regulation of mucosal immune responses T reg cells, dendritic cells, colitis, mucosal, Crohn's disease, transgenic, IgA, Th IL17