Pathobiology and Molecular Medicine  http://www.gbs.uab.edu  http://www.uab.edu/graduate  Back to Main
 Faculty Listing
Total Records: 132
Last Name First Name Research/Clinical Interest Title Keywords
FALANY CHARLES Biochemical and physiological properties of human cytosolic sulfotransferases
WHITE CHARLES
ABSHER DEVIN
FANUCCHI MICHELLE
GALIN F. Neuroimmunology/Multiple Sclerosis
HABEGGER KIRK FGF21 as mediator of the metabolic actions of glucagon & Duodenal nutrient exclusion enhances glucose metabolism via CNS regulation
QIN HONGWEI
BLALOCK JAMES Rational Drug and Vaccine Design/Neutrophilic Inflammation
EDBERG JEFFREY Genetic Polymorphisms in Wegener’s Granulomatosis
HABLITZ JOHN Cellular Mechanisms of Neurotransmission
SCHWIEBERT LISA Airway inflammation; lung function; asthma and exercise
PREUSS MEREDITH
DETLOFF PETER Mouse Models of Human Genetic Disorders
GOEPFERT PAUL Determining the mechanisms allowing T cells to control HIV replication in vivo
SMITH PETER The role of the membrane cytoskeleton in regulating the cell surface expression of epithelial transport proteins.
KRAFT TIMOTHY Physiology and Pathophysiology of Photoreceptors
BALLINGER SCOTT Environmental cardiology, free radical biology, mitochondrial function, mitochondrial - nuclear interactions mitochondria, oxidative stress, evolutionary medicine, cardiovascular disease, cancer, metabolism
BHATNAGAR SUSHANT Identification and characterization of novel factors in insulin secretion in obesity and type 2 diabetes Obesity, Type 2 Diabetes, Beta Cell Biology, Insulin Secretion, SNARE Biology, Secreted Proteins, Insulin Granule Trafficking, Tomosyn Proteins, Post-translational Modifications
BEVENSEE MARK Cellular and Molecular Physiology of Acid-base Transporters and pH Regulation acid-base, bicarbonate, transporter, brain, fluorescence dyes, glia , heart, intracellular pH, microelectrodes, neuron, Xenopus oocyte, neuronal firing, kidney, polycystic kidney disease, epithelial sodium channel
ZHENG X. LONG Molecular Mechanisms of Normal and Abnormal Blood Clotting; Inflammation and Microvascular Thrombosis; CRISPR/Cas9 Gene Editing as a Novel Therapeutic Strategy for Thrombotic Diseases ADAMTS13, von Willebrand factor, TTP, Arterial thrombosis, Vascular biology, Autoimmunity, and Inflammation, CRISPR/Cas9 Gene Editing
BULLARD DANIEL Regulation of Immune and Inflammatory Responses adhesion molecules, lupus, vasculitis, psoriasis
KADISHA INGA The role of white matter changes in aging and Alzheimer's disease Alzheimer's Disease, Aging, Cognition
VAN GROEN THOMAS Treatment of Alzheimer's disease with small abeta-oligomer binding peptides Alzheimer's disease, pathology, amyloid beta, peptides, cognition, behavioral assessment
DEVILLIERS PATRICIA Novel Target for Head and Neck Cancer: The Sonic Hedgehog Pathway ameloblastoma, sonic hedgehog, odontogenic tumors, head and neck pathology,
MURPHY-ULLRICH JOANNE Extracellular Matrix Control of Cell and Growth Factor Function, multiple myeloma, diabetic complications, glaucoma atherosclerosis, diabetic complications, tumor microenvironment, multiple myeloma, osteolytic bone disease, glaucoma, fibrosis, TGF-beta, thrombospondin
ZHANG JIANHUA Mechanisms and regulation of autophagy-lysosomal pathway in health and diseases Autophagy, Parkinson's Disease, Alzheimer's disease, heart disease, lysosomes, mitochondria, redox signaling
SHACKA JOHN Targeting the Autophagy-Lysosome Pathway for Therapeutic Benefit in Parkinson's Disease Autophagy; Lysosome; Parkinson's; Synuclein; Alpha-Galactosidase
OPARIL SUZANNE role of inflammation/vascular injury and repair; clinical/population-based research in special populations, translational research in resistant hypertension, role of oxidative stress/free radical injury in the pathogenesis of hypertension blood pressure, cardiovascular disease prevention, hypertension, vascular biology, nutrition, nephrology, cardiovascular physiology
OLSEN MICHELLE Understanding the function of astrocytes during normal and aberrant development brain injury, neurodevelopmental disorders, spinal cord, astrocyte, potassium channel, glutamate transporter, epigenetics
PONNAZHAGAN SELVARANGAN Experimental Cancer Therapeutics and BOne Diseases: From Basic to Preclinical Studies Breast Cancer; Prostate Cancer; Osteoimmunology; Bone Metastasis; Osteogenesis; Bone Fracture; Stem Cell Therapy
HSU HUI-CHEN The BXD2 autoimmune mouse model of lupus and erosive arthritis BXD2, lupus, arthritis, IL-17, type I IFN, apoptotic cells
KNIGHT JOHN Oxalate Handling and Synthesis and its Relationship to Health and Disease Calcium oxalate kidney stone disease, Oxalobacter formigenes, primary hyperoxaluria
PENG JI-BIN Calcium transport proteins and their roles in health and disease Calcium transport, absorption, reabsorption, hyercalciuria, hypertension, TRPV6, TRPV5, WNK4
OJESINA AKINYEMI Interplay of Genomic Alterations and Microbial Influences in Cancer cancer, infection, genomics, transcriptome, HIV, HPV, EBV, cervical, lymphoma, early detection, recurrence, precancerous, progression, mutations, microbiome, viral, RNASeq, diagnostics, therapy, global health, molecular epidemiology, women's health
LU RUI Epigenetic Mechanisms in Cancer Initiation, Maintenance, and Drug Resistance Cancer, Leukemia, Epigenetics, Genomics, Chromatin, Gene regulation, Novel therapeutics
ANDERSON PETER Cardiovascular Pathophysiology and Health Sciences Education Cardiovascular pathology, animal models of human disease, technology enhanced education
HARRINGTON LAURIE Protective and Pathogenic CD4 T Cell Responses CD4 T cells, autoimmunity, immunological memory, cytokines
SONTHEIMER HARALD The Role of Neuroglia in Brain Function and Disease Cell migration, brain development, primary brain tumors, glioma, astrocytes, oligodendrocytes, stem cells, regeneration
YODER BRADLEY Cilia Signaling and Dysfunction in Development and Disease Cilia, cystic kidney diseases, obesity, signal transduction, cell fate determination and embryonic patterning, birth defects, mouse and C. elegans models.
LEAL SIXTO Infectious Disease Diagnostics, Drug Discovery, and Effector Functions of Phagocytic Cells Clinical Microbiology, Medical Microbiology, Molecular Diagnostics, Microbiology, Neutrophils, PMNs, fungi, mold, mollicutes
MANNE UPENDER Translational research in grastrointestinal malignancies and breast cancer Colorectal Cancer, Breast Cancer, Molecular Biomarkers, Racial/Ethnic Disparities, Cancer Control & Prevention
SONG YUHUA An integrated multi-scale computational modeling and biological experimental research program to study apoptosis, cell adhesion and biomaterial design Computational Biology/Biomechanics, Mechanotransduction, Protein/Biomembrane structure and function, death receptor-mediated apoptosis, Cell adhesion, Biomaterials
COLLAWN JAMES Role of ion channels in cystic fibrosis Cystic Fibrosis; Endocytosis; Protein Trafficking, chymase, heart failure
SERRA ROSA Mechanism of TGF-ß Action in Developmental and Disease Processes developmental biology, bone, cartilage, teeth, intervertebral disc, osteoarthrits, skeletal disease
BANERJEE RONADIP Pancreatic Beta-Cell Biology; Molecular mechanisms of beta-cell adaptation during pregnancy and dysregulation in gestational diabetes diabetes mellitus, prolactin receptor, beta-cell biology, pregnancy, transcriptional regulation
WENDE ADAM Glucose-mediated remodeling of cardiac DNA methylation Diabetes, Hypertension, Exercise, Mitochondria, Metabolism, Glucose, Epigenetics, Gene expression, transcription, O-GlcNAc, protein modifications, DNA methylation, Histone modification, GLUT4, PDK2, PDK4
HUNTER CHAD Transcriptional control of pancreatic beta cell development and adult islet cell function Diabetes, Transcription Factor, Coregulators, Gene Regulation, Organogenesis, Pancreas, Chromatin, Developmental Biology, Endocrinology
BALKOVETZ DANIEL Epithelial Cell Biology; Epithelial Cell Signal Regulation; Regulation of paracellular transport across epithelial cell tight junctions epithelial cells, claudins, tight junctions, E-cadherin, hepatocyte growth factor, ERK, MDCK
SAMANT RAJEEV Tumor progression and metastasis of cancer. Epithelial-Mesenchymal-Transition, mylti-protein complexes, transcription regulation, nucleolus, protein stability, chaperones, Hest shock proteins
ELTOUM ISAM-ELDIN - Clinical research in diagnostic cytology and surgical pathology- Tumorogenesis of prostate cancer and chemoprevetion - HPV infection EUS-FNA, Prostate cancer in transgenic animals, HPV infection, Cytology, Immunopathology
BAMMAN MARCAS Exercise as a discovery tool and treatment in regenerative medicine and medical rehabilitation. exercise medicine, medical rehabilitation, regenerative medicine, clinical trial, muscle biology
LORENZ ROBINNA Mucosal Immunology gastritis, helicobacter, inflammatory bowel disease, mucosal immunology, asthma, diabetes
BASU MALAY Computational Genomics and Bioinformatics Genomics, bioinformatics, high-performance computing, grid computing, computational biology, evolution
DICKINSON DALE Redox cell signaling and environmental exposures; natural products and chemoprevention glutathione; redox; Nrf2; antioxidant; microRNA; nutraceutical
BARNES JARROD Mechanisms of metabolic dysregulation and aberrant glycosylation in pulmonary disease glycosylation, pulmonary vascular disease, metabolism
FRANK STUART Growth Hormone Action and GH Receptor Structure and Function growth hormone, signaling, prolactin, IGF-1, growth factors
PRABHU SUMANTH Mechanisms of cardiac remodeling and repair in heart failure heart failure, ventricular remodeling, stem cells, inflammation, cardiac function
AGARWAL ANUPAM Regulation of heme oxygenase gene expression in kidney and vascular injury heme oxygenase, acute kidney injury, transplant nephrology, transcriptional gene regulation
GRAY MICHELLE Pathogenesis of Huntington's Disease Huntington's disease, neurodegeneration, neuroscience, astrocytes
POLLOCK DAVID Hypertension and Renal Disease hypertension, diabetes, sickle cell, hemodynamics, endothelin, nitric oxide, kidney, sodium
LEAVENWORTH JIANMEI Cancer-Immune cell Crosstalk: Discovery of new targets for cancer immunotherapy Immunology, Cancer Immunology, Immunotherapy, Treg, NK cells, glioma
DAVIS RANDALL The developmental immunology of lymphocytes and immunoreceptor biology. Lymphoproliferative disorders and mechanisms that contribute to lymphomagenesis and autoimmunity. Immunology, lymphoproliferative disorders, autoimmunity, B cells, Fc receptors, CLL, FCRL
HEL ZDENEK Immunology and pathogenesis of HIV-1 / AIDS; Neutrophil biology; Effect of hormonal contraception on immune system; Design of novel strategies for immunotherapy of cancer. Immunology, Neutrophils, HIV-1, Vaccine, Cancer.
ZAJAC ALLAN Anti-Viral Immunity; T Cell Responses; Immunological Memory Immunology, Virology, Pathogenesis, Vaccines, T cells
MAYNARD CRAIG Intestinal Immune Regulation in Health and Disease immunoregulation, microbiota, inflammatory bowel disease (IBD)
BUCHSBAUM DONALD Cancer immunotherapy Immunotherapy, Wnt inhibitors, pancreatic cancer, breast cancer, ovarian cancer
KIM JEONGA Cross-talk between inflammation and insulin signaling Insulin Resistance, Endothelial Dysfunction, NO, ROS, Polyphenol
MESSINA JOSEPH Insulin and Growth Hormone (GH) Action, Insulin and GH Resistance Following Injury/Trauma, Infection and Polytrauma Insulin Resistance, Growth Hormone Resistance, Signal Transduction, Gene Expression, Stress, Injury, Trauma, Infection, Polytrauma
GARVEY W. Molecular and physiological pathogenesis of human insulin resistance Insulin resistance, obesity, Metabolic Syndrome, Type 2 Diabetes
MCNICHOLAS-BEVENSEE CARMEL Regulation of ion channels Ion channel, Pulmonary, Cardiovascular, Sweat gland
RAMANADHAM SASANKA Role of Lipid Mediators in Signal Transduction Islets, signal transduction, iPLA2, bone, protease inhibitors
CRON RANDALL CD4 T Lymphocyte Transcriptional Regulation Lupus, HIV-1, CD4 T Cell, Transcription, Nuclear Factor of Activated T Cells, Macrophage Activation Syndrome, Temporomandibular Joint (TMJ)
HILDRETH BLAKE Role of macrophages and osteoclasts in bone metastasis and primary bone tumors macrophage, osteoclast, breast cancer, primary bone tumor, bone, metastasis
BEBOK ZSUZSANNA Molecular mechanisms by which cellular stress responses such as the unfolded protein response (UPR) contribute to the pathology of human disorders. membrane proteins, ER stress, UPR, SNP, mutation, CFTR, micro-RNA
ALLER STEPHEN Structure and Function of Human Membrane Proteins Research/Clinical Membrane proteins, structure-based drug design, x-ray crystallography, biophysics, biochemistry, pharmacology, blood-brain barrier, cystic fibrosis, multi-drug resistance, drug transport, breast cancer
HURST DOUGLAS Molecular mechanisms of cancer metastasis metastasis, breast cancer, chromatin modification, microenvironment, tumor progression
GRAY MICHAEL Bacterial responses to oxidative stress microbiota, redox, stress, probiotics, reactive chlorine, inflammation
INSCHO EDWARD Physiology and pathophysiology of the renal microcirculation microcirculation, afferent arterioles, autoregulation, inflammation, purinoceptors, endothelin, renal injury, Toll-like receptor 4 (TLR4)
MITRA KASTURI Exploring the significance of mitochondrial structural change in health and disease Mitochondria, Cell proliferation, Energetics, Cancer, Stem cells
DARLEY-USMAR VICTOR Mitochondrial Health; Bench to Bedside mitochondria, nitric oxide, reactive oxygen species, bioenergetic dysfunciton, translational research
MITCHELL TANECIA The Role of Mitochondria in Immune Cells in Urological Disorders Mitochondria, Oxidative Stress, Inflammation, Immune Cells, Kidney Stones, Interstitial Cystitis/Painful Bladder Syndrome
ZHOU LUFANG Mitochondrial dysfunction and oxidative stress in human disease mitochondrial biology, cardiovascular disease, multiscale computational modeling, live cell imaging, optogenetics
BAILEY SHANNON Molecular mechanisms of chronic alcohol and obesity induced fatty liver disease Molecular mechanisms of alcohol and obesity induced liver diseases; Mitochondrial dysfunction in disease; Molecular bioenergetics; Circadian biology; Functional proteomics; Nitric oxide; Free radical biology; Toxicology
WANG JIANBO The Planar Cell Polarity Pathway in mammalian embryogenesis mouse genetics, morphogenesis, cell polarity
CHATHAM JOHN Cardiomyocyte function and survival in ischemia/reperfusion and the impact of diabetes: Myocardial ischemia, diabetic cardiomyopathy, O-GlcNAc, STIM1, Ca2+-signaling
YANG EDDY Targeting DNA repair pathways to augment the therapeutic ratio for cancer patients nanostring, profiling, DNA damage, DNA repair, EGFR, cancer, PARP, apoptosis, brain, protection, GSK3
ROBERSON ERIK Neurobiology of Alzheimer's Disease and Frontotemporal Dementia Neurodegeneration, Alzheimer's disease, frontotemporal dementia, tau, progranulin, excitability, signaling, plasticity, behavior
KANO SHINICHI Immunology of brain homeostasis and disease Neuroimmunology, Glia, Cytokine, Epigenetics, Extracellular vesicles, Schizophrenia
KIM HELEN Proteomics of neuroprotective and chemopreventive actions of dietary phytochemicals neuroprotection, proteomics, protein modifications, antioxidant dietary supplements, menopause, neurogenesis
HYNDMAN KELLY Novel mechanisms of HDAC1 regulation of collecting duct function. nitric oxide, endothelin, collecting duct, histone deacetylase, Aquaporin-2
PLACZEK WILLIAM Anti-cancer target validation and structure-based drug discovery. NMR spectroscopy, cancer, drug discovery, peptide synthesis, structural biology, apoptosis, signaling
FERNANDEZ JOSE Genetic basis for racial/ethnic differences in obesity and metabolic outcomes obesity, nutriton, genetics, genetic admixture, racial disparities
ZAYZAFOON MAJD The Role of Calcium Signaling in the pathogenesis of disease Osteoblasts, Bone, Prostate Cancer, Osteosarcoma, Calmodulin Kinase, NFAT, AP-1, Bone metastasis, HDAC, histone acetylation, DNA methyltransferase
LI YI-PING Investigating the mechanisms of skeletal and craniofacial development, tumorigenesis and cancer metastasis; as well as developing effective new therapies for the treatment and prevention of related diseases. Osteoclasts, Osteoblasts, Bone formation and bone resorption, Skeletal development, Tumorigenesis, Cancer bone metastasis, Muscular development, Brain and craniofacial development, Skeleto-muscular disease, and Anti-cancer drug discovery
LIU RUI-MING Oxidative stress, Aging, Lung fibrosis, Alzheimer's disease
HARDY ROBERT Translational research oxidative stress, cancer, insulin resistance
STANDAERT DAVID Translational Research in Neurodegenerative Diseases Parkinsons Disease, Dystonia, Movement Disorders
VOLPICELLI-DALEY LAURA Cognitive impairments in Parkinson's disease and Lewy body dementias Parkinson's disease, Lewy body dementias, synuclein, tau, glucocerebrosidase, cell biology of the neuron, neurodegeneration
YACOUBIAN TALENE Role of 14-3-3 proteins in Parkinson’s disease Parkinsons disease; Neurobiology; Molecular Genetics & Disease
LIMDI NITA Pharmacogenomics research and Implementation Science Personalized Medicine, Precision Medicine, Pharmacogenomics, Implemental Science, Pharmacoepidemiology, Pharmacoeconomics, Warfarin , Antiplatelet drugs, Antithrombotic, comparative effectiveness