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Faculty Detail    
Campus Address NP 3551 Zip 7331
Phone  (20-5) -488
Other websites

Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Pathology   Anatomic Pathology Assistant Professor
Center  General Clinical Research Center  Ctr for Clinical & Translational Sci Assistant Professor

Graduate Biomedical Sciences Affiliations
Molecular and Cellular Pathology Program 

Biographical Sketch 
I attended the University of Georgia as an undergraduate and went on to study medicine at the Medical College of Georgia. I am a pathologist trained in anatomic and clinical pathology at the University of Alabama, with two years of fellowship experience including a year of surgical pathology fellowship as well as a year of training in gastrointestinal and hepatobiliary pathology. I also serve as staff anatomic pathologist for the Birmingham Veteran's Administration Medical Center.

Society Memberships
Organization Name Position Held Org Link
Medical Association of the State of Alabama  Member   
United States and Canadian Academy of Pathology  Member   
American Society of Clinical Pathology  Member   
College of American Pathologists  Fellow   

Research/Clinical Interest
I am interested in studying the multifactorial issues underlying racial disparity in liver disease outcomes. Particularly, I am interested in the the possible molecular basis for disparities in the evolution of chronic liver disease and hepatocellular carcinoma. I also hold a general interest in GI pathology and GU pathology

Selected Publications 
Publication PUBMEDID
JQ1 Induces DNA Damage and Apoptosis, and Inhibits Tumor Growth in a Patient-Derived Xenograft Model of Cholangiocarcinoma. Garcia PL, Miller AL, Gamblin TL, Council LN, Christein JD, Arnoletti JP, Heslin MJ, Reddy S, Richardson JH, Cui X, van Waardenburg RCAM, Bradner JE, Yang ES, Yoon KJ. Mol Cancer Ther. 2018 Jan;17(1):107-118. doi: 10.1158/1535-7163.MCT-16-0922.  doi: 10.1158/1535-7163.MCT-16-0922. 
Association between Hepatitis C Virus Infection, P53 Phenotypesand Gene Variants of Adenomatous Polyposis Coli in Hepatocellular Carcinomas. Council, Leona, Chandrakumar, Shanmugan, et al. Journal of Digestive Diseases and Hepatology. J Dig Dis Hepatol 2016: JDDH-121   
Endoscopic characterization and resection of Vanek's tumor of the duodenum.
Kröner PT, Council L, Mönkemüller K.
Endoscopy. 2015;47 Suppl 1 UCTN:E408-9. doi: 10.1055/s-0034-1392595. Epub 2015 Aug 14.

(Abstract) Clinical Relevance of p53 Codon 72 Polymorphisms in Hepatocellular Carcinomas. Leona N. Council, Chandrakumar Shanmugam, Venkat R. Katkoori, Meenakshi Sthanam, Alex Hanna, Upender Manne. CCTS/MHRC retreat November 2011.   
(Abstract) Clinical Relevance of APC and p53 Gene Variants in Hepatocellular Carcinomas. Leona N. Council, M.D., Chandrakumar Shanmugam, M.D., Venkat R. Katkoori, Ph.D., Meenakshi Sthanam, B.S., Alex Hanna, M.D., and Upender Manne, Ph.D. UAB Comprehensive Cancer Center 14th Annual Research Retreat, 2011.   
Development and histopathological characterization of tumorgraft models of pancreatic ductal adenocarcinoma. Garcia PL, Council LN, Christein JD, Arnoletti JP, Heslin MJ, Gamblin TL, Richardson JH, Bjornsti MA, Yoon KJ. PLoS One. 2013 Oct 23;8(10):e78183.
Over-the-scope clip-assisted method for resection of full-thickness submucosal lesions of the gastrointestinal tract.
Sarker S, Gutierrez JP, Council L, Brazelton JD, Kyanam Kabir Baig KR, Mönkemüller K.
Endoscopy. 2014 Sep;46(9):758-61.
Poor agreement between endoscopists and gastrointestinal pathologists for the interpretation of probe-based confocal laser endomicroscopy findings.
Peter S, Council L, Bang JY, Neumann H, Mönkemüller K, Varadarajulu S, Wilcox CM.
World J Gastroenterol. 2014 Dec 21;20(47):17993-8000.
The Lower Anogenital Squamous Terminology Standardization project for HPV-associated lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology.
Darragh TM, Colgan TJ, Thomas Cox J, Heller DS, Henry MR, Luff RD, McCalmont T, Nayar R, Palefsky JM, Stoler MH, Wilkinson EJ, Zaino RJ, Wilbur DC; Members of the LAST Project Work Groups. Int J Gynecol Pathol. 2013 Jan;32(1):76-115. doi: 10.1097/PGP.0b013e31826916c7. Erratum in: Int J Gynecol Pathol. 2013 Mar;32(2):241. Int J Gynecol Pathol. 2013 Jul;32(4):432.
Cholesterolosis. Performance Improvement Program Critique (Case #2010-11). Leona Council, M.D. and Dr. Gene Siegal, M.D., Ph.D.   
Endoscopic resection and enucleation of gastric submucosal tumor facilitated by subsequent closure of incision using over-the-scope clip.Abe S, Council L, Cui X, Saito Y, Mönkemüller K.
Endoscopy. 2015;47 Suppl 1 UCTN:E153-4. doi: 10.1055/s-0034-1391254. Epub 2015 Apr 21.