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Faculty Detail    
Name ELIZABETH E. BROWN
  
Campus Address WTI 602C Zip 3300
Phone  (20-5) -105
E-mail  elbrown@uab.edu
Other websites
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Pathology   Molecular & Cellular Pathology Professor
Secondary  Medicine  Med - Immunology/Rheumatology Associate Professor
Secondary  Microbiology  Microbiology Professor
Center  Comp Arthritis, MSK, Bone & Autoimmunity Ctr  Comp Arthritis, MSK, Bone & Autoimmunity Ctr Professor
Center  Comprehensive Cancer Center  Comprehensive Cancer Center Professor
Center  General Clinical Research Center  Ctr for Clinical & Translational Sci Professor
Center  General Clinical Research Center  Minority Health & Research Center Professor
Center  General Clinical Research Center  Nephrology Research & Training Center Professor

Graduate Biomedical Sciences Affiliations
Genetics, Genomics and Bioinformatics 
Immunology 
Integrative Genetics Graduate Program 
Medical Scientist Training Program 



Research/Clinical Interest
Title
Molecular and Genetic Epidemiology of Immune-Mediated Clinical Phenotypes
Description
The research conducted in Dr. Brown’s laboratory is mainly targeted to advance the understanding of aberrant immune function common to inflammatory-mediated chronic diseases, such as select autoimmune diseases as well as multiple myeloma and related precursor states, each with underlying B cell pathology. Within this purview, she uses a multidisciplinary functional genomics approach to explore pathways involved in chronic immune perturbation, inflammation as modifiers of disease, and B cell homeostasis. The objective of this research is to identify and validate molecular biomarkers, which may be used to target high-risk populations to improve disease surveillance and modify therapeutic intervention leading to significant reductions in morbidity and mortality associated with advanced stage disease.

Keywords
multiple myeloma, autoimmune, lupus, genetics, genomics, epidemiology