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 Faculty Listing
Total Records: 63
Last Name First Name Research/Clinical Interest Title Keywords
ALLER STEPHEN Structure and Function of Human Membrane Proteins Research/Clinical Membrane proteins, structure-based drug design, x-ray crystallography, biophysics, biochemistry, pharmacology, blood-brain barrier, cystic fibrosis, multi-drug resistance, drug transport, breast cancer
AMM HOPE Genetics and Pharmacology of Oral Tumors oral cancer, squamous cell carcinoma, HNSCC, genetics, hedgehog siganling, pharmacology
BALKOVETZ DANIEL Epithelial Cell Biology; Epithelial Cell Signal Regulation; Regulation of paracellular transport across epithelial cell tight junctions epithelial cells, claudins, tight junctions, E-cadherin, hepatocyte growth factor, ERK, MDCK
BALLINGER SCOTT Environmental cardiology, free radical biology, mitochondrial function, mitochondrial - nuclear interactions mitochondria, oxidative stress, evolutionary medicine, cardiovascular disease, cancer, metabolism
BELLIS SUSAN Role of glycosylation in tumor progression and metastasis tumorigenesis, metastasis, cancer stem cell, cell invasion, apoptosis, tumor immunology,
BJORNSTI MARY-ANN DNA topoisomerase I, yeast genetics, cancer chemotherapeutics, TOR signaling, SUMOylation, DNA damage response, drug resistance, siRNA screening, breast cancer
CHANG CHENBEI Growth Factor Signaling and Transcription Regulation in Vertebrate Development TGF-beta, neural induction, BMP, ErbB, gastrulation, cell movement
CHEN YABING Gene Regulation and Function in the Pathogenesis of Cardiovascular Disease and Aging vascular smooth muscle cells, excellular matrix, vascular calcification, atherosclerosis, diabetes, aging
DAVIS RANDALL The developmental immunology of lymphocytes and immunoreceptor biology. Lymphoproliferative disorders and mechanisms that contribute to lymphomagenesis and autoimmunity. Immunology, lymphoproliferative disorders, autoimmunity, B cells, Fc receptors, CLL, FCRL
DING QIANG Molecular mechanisms of organ fibrosis Signal Transduction; Cell Physiology, Adhesion & Migration Signaling; Molecular Genetics & Disease; Gene Regulation and Expression
ELTOUM ISAM-ELDIN - Clinical research in diagnostic cytology and surgical pathology- Tumorogenesis of prostate cancer and chemoprevetion - HPV infection EUS-FNA, Prostate cancer in transgenic animals, HPV infection, Cytology, Immunopathology
FALANY CHARLES Biochemical and physiological properties of human cytosolic sulfotransferases
FENG XU The RANKL/RANK/OPG System in Health and Disease RANKL, RANK, OPG, Cell Differentiation, Cell Signaling, Osteoclast, Mammary Gland, Breast Cancer
FRANK STUART Growth Hormone Action and GH Receptor Structure and Function growth hormone, signaling, prolactin, IGF-1, growth factors
FULLER CATHERINE ENaC/ASIC Ion Channels; Sodium channels, glioma, migration, proliferation, cancer, signaling, polycystic kidney disease
HAN XIAOSI Epigenetic Regulation in Glioblastoma glioblastoma, protein argine methyltransferase-5, glioma stem cell, epigenetics
HARDY ROBERT Translational research oxidative stress, cancer, insulin resistance
HARTMAN JOHN Experimental models of gene interaction networks that buffer human disease using cell array phenotyping of yeast gene knockout libraries yeast genetics, quantitative high throughput cell array phenotyping (Q-HTCP), gene interaction networks, cellular quiescence, aging, cystic fibrosis, chemotherapy response, systems biology, drug discovery, lab automation
HEL ZDENEK Immunology and pathogenesis of HIV-1 / AIDS; Neutrophil biology; Effect of hormonal contraception on immune system; Design of novel strategies for immunotherapy of cancer; Covid-19. Immunology, Neutrophils, HIV-1, Vaccine, Cancer, Covid-19.
HILDRETH BLAKE Role of macrophages and osteoclasts in bone metastasis and primary bone tumors macrophage, osteoclast, breast cancer, primary bone tumor, bone, metastasis
HJELMELAND ANITA Targeting Brain Tumor Initiating Cells and the Tumor Microenvironment Brain Tumor, Tumor Microenvironment, Tumor Initiating Cell, Cancer Stem Cell
HU HUI Transcriptional Regulation of Adaptive Immunity Tfh cell differentiation, GC responses, CD8+ T cell quiescence/activation, T cell responses, immune memory, vaccines
JAVED AMJAD Genetic and Molecular Signaling for Cellular Differentiation and Skeletogenesis Osteoblast, Bone Development, Gene Regulation, Osteoporosis
KARTHIKEYAN MYTHREYE Molecular and cellular mechanisms of signaling during metastasis ovarian cancer, TGFbeta, BMP, inhibin/activin, betaglycan, cellular signaling, extracellular matrix , cell survival mechanisms
KING PETER 1) RNA Regulation of Inflammation in ALS and other Neurodegenerative Disorders, 2) Smads as Biomarkers of ALS Disease Progressionh RNA stability; AU-rich elements; cytokines and chemokines; glioblastoma; amyotrophic lateral sclerosis, stroke, spinal cord injury, HuR, KSRP
KLUG CHRISTOPHER Hematopoietic stem cell biology, acute leukemia, and pancreatic cancer
KORF BRUCE Neurofibromatosis Type 1 neurofibromatosis; neurogenetics; molecular diagnosis, genomic medicine
KRISHNA NEPALLI Structural Biology and Biomolecular NMR Spectroscopy Proteins, Structural Biology, NMR
LAHTI ADRIENNE Neuroimaging psychiatry, schizophrenia, research, lahti
LARIMER BENJAMIN Development of Novel Biological Agents to Personalize Cancer Therapy Immunotherapy, Phage Display, Nanobodies, Molecular Imaging
LEAVENWORTH JIANMEI Cancer-Immune cell Crosstalk: Discovery of new targets for cancer immunotherapy Immunology, Cancer Immunology, Immunotherapy, Treg, NK cells, glioma
LIN DIANA head and neck pathology, cytopathology, endocrine pathology, pulmonary pathology, dermatopathology
LIU RUNHUA Cancer Cell Biology and Cancer Genetics
LU RUI Epigenetic Mechanisms in Cancer Initiation, Maintenance, and Drug Resistance Cancer, Leukemia, Epigenetics, Genomics, Chromatin, Gene regulation, Novel therapeutics
MANNE UPENDER Translational research in grastrointestinal malignancies and breast cancer Colorectal Cancer, GI malignancies, Breast Cancer, Molecular Biomarkers, Racial/Ethnic Disparities, Cancer Control & Prevention
MARKERT JAMES Engineering Herpes Simplex Viruses for the Therapy of Cancer glioma, gene therapy, brain tumors, herpes simplex, cancer therapy, immunotherapy, anti-angiogenic therapy
MITRA KASTURI Exploring the significance of mitochondrial structural change in health and disease Mitochondria, Cell proliferation, Energetics, Cancer, Stem cells
MURPHY-ULLRICH JOANNE Extracellular Matrix Control of Cell and Growth Factor Function, multiple myeloma, diabetic complications, glaucoma atherosclerosis, diabetic complications, tumor microenvironment, multiple myeloma, osteolytic bone disease, glaucoma, fibrosis, TGF-beta, thrombospondin
NORIAN LYSE Understanding the effects of diet and obesity on anti-tumor immunity cancer immunology, immunotherapy, obesity, diet, kidney cancer, breast cancer
PARANT JOHN Animal Models of Genomic Instability, p53 Regulation, Cancer and Mitotic Dysfunction Zebrafish, Mouse, Li Fraumeni Syndrome, Roberts syndrome, Birth Defects, Tumor Suppressor, Genomic Instability, Aneuploidy, Mitosis, DNA damage, Cancer, and Apoptosis.
PATEL RAKESH Modulation of Inflammation by Reactive Species and N-glycans vascular, hemoglobin, red cells, Inflammation, isoflavones, Nitric oxide, nitrite, N-glycan, matrikine
PLACZEK WILLIAM Anti-cancer target validation and structure-based drug discovery. NMR spectroscopy, cancer, drug discovery, peptide synthesis, structural biology, apoptosis, signaling
PONNAZHAGAN SELVARANGAN Experimental Cancer Therapeutics and BOne Diseases: From Basic to Preclinical Studies Breast Cancer; Prostate Cancer; Osteoimmunology; Bone Metastasis; Osteogenesis; Bone Fracture; Stem Cell Therapy
REN BIN Epigenetic and Transcriptional Regulation of Functional Angiogenesis and Arteriogenesis in Cancer, Heart and Vascular Diseases, Alzheimer's Disease and Diabetes. Endothelial cells, Angiogenesis, Arteriogenesis, Molecular and cellular biology, Cancer, Ischemic heart and vascular diseases, Diabetes, Alzherimer's disease
RENFROW MATTHEW Analysis of Protein Glycosylation in Human Disease by High Resolution Mass Spectrometry Fourier transform mass spectrometry (FT-MS), protein glycosylation, IgA O-glycosylation, IgA nephropathy, proteomics, glycoproteomics
SAMANT RAJEEV Tumor progression and metastasis of cancer. Ribosome Biogenesis, Epithelial-Mesenchymal-Transition, mylti-protein complexes, transcription regulation, nucleolus, protein stability, chaperones, Hest shock proteins
SANDERSON RALPH Molecular Regulation of the Tumor Microenvironment tumor, microenvironment, cancer, heparan sulfate, proteoglycan, heparanase, exosomes, metastasis, bone, myeloma, breast cancer, drug resistance
SHEVDE-SAMANT LALITA Investigating molecular signaling mechanisms that present as fundamental aberrations in tumor cells or their immune microenvironment Tumor progression, metastasis, innate and adaptive immune microenvironment, signaling, cancer stem cells, chemoresistance, metabolism, osteolysis, Merlin, Hedgehog pathway, Wnt pathway
SHRESTHA SADEEP
SIEGAL GENE Gene therapy of solid tumors, cancer biology, tumors of bone Bone Tumors, Cancer Gene Therapy, Invasion and Metastasis
SINGH KESHAV Mitochondrial Metabolism, Mitochondria-to-Nucleus Retrograde Cross Talk, Oxidative Stress, Genomic Instability and Its Role in Tumor Progression and Metastasis mitochondria, genomic instability, cancer, breast cancer, prostate, arsenic, oxidative stress, metabolism, tumor progression, tumor metastasis
SONG YUHUA An integrated multi-scale computational modeling and biological experimental research program to study apoptosis, cell adhesion and biomaterial design Computational Biology/Biomechanics, Mechanotransduction, Protein/Biomembrane structure and function, death receptor-mediated apoptosis, Cell adhesion, Biomaterials
STRONG THERESA Identification of Tumor Antigens and Development of Cancer Vaccines gene therapy, immunotherapy, vaccine, Phase I clinical trials
TANG JIANMING Genetic and Epigenetic Correlates of Infection and Immunity Immunogenetics, Infectious Disease, Pharmacogenetics, Public Health
TOLLEFSBOL TRYGVE
VAN WAARDENBURG ROBERT Structure-Function analysis of Tyrosyl-DNA phosphodieasterase I; Developing a DNA Repair Enzyme as Therapeutic Target for Anti-Cancer Treatment Structure-function analysis, Mechanism of Action of proteins and drugs (chemotherapeutics), Drug Development for novel therapeutic targets, Post-translational modification by Ubiquitin and SUMO (Small Ubiqitin like modifier), Protein interactions
VARAMBALLY SOORYANARAYANA Cancer molecular genetics, Cancer Biomarker Discovery, Cancer Biology and Therapeutic Targeting UALCAN, TCGA, CPTAC, Genomics, Bioinformatics, Proteomics, Biomarker, Integrative Cancer Biology and Therapeutics.
WELNER ROBERT Studying the bone marrow microenvironment during steady-state, inflammation, or leukemia stem cell, hematopoiesis, niche, stromal cells, immune response, leukemia
XU HUI The role of IL-17 in inflammation associated tumor development T cells, dendritic cells, cytokines, tumor suppressor
XU JIA Investigating the mechanisms by which oncogenic signaling pathways impact tumor cell division, growth and metastasis AURKB, PI3K/AKT/PTEN pathway, Mitosis, Cancer Biology, Cancer signaling pathway, PROTAC, AAV gene therapy
YANG EDDY Targeting DNA repair pathways to augment the therapeutic ratio for cancer patients nanostring, profiling, DNA damage, DNA repair, EGFR, cancer, PARP, apoptosis, brain, protection, GSK3
YUSUF NABIHA Innate immune mechanisms in tumor development toll like receptors, type I interferons, immune system, cancer, T-cells
ZAYZAFOON MAJD The Role of Calcium Signaling in the pathogenesis of disease Osteoblasts, Bone, Prostate Cancer, Osteosarcoma, Calmodulin Kinase, NFAT, AP-1, Bone metastasis, HDAC, histone acetylation, DNA methyltransferase