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Faculty Detail    
Name LIOU Y SUN
 
Campus Address CH 494B Zip 1170
Phone
E-mail  sunlab@uab.edu
Other websites https://www.uab.edu/cas/biology/people/faculty/liou-y-sun
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Biology  Biology Associate Professor
Secondary  Neurobiology  Neurobiology Assistant Professor
Center    Associate Professor
Center  Neurology   Alzheimer's Disease Center Associate Professor
Center  Comprehensive Diabetes Center  Comprehensive Diabetes Center Associate Professor
Center  General Clinical Research Center  Comprehensive Neuroscience Center Associate Professor
Center  Integrative Center for Aging Research  Integrative Center for Aging Research Associate Professor
Center  Nutrition Sciences   Nutrition Obesity Res Ctr (NORC) Associate Professor

Graduate Biomedical Sciences Affiliations
Cell, Molecular, & Developmental Biology 
Genetics and Genomic Sciences 
Integrative Biomedical Sciences 
Microbiology 
Neuroscience 



Research/Clinical Interest
Title
Aging, longevity and Alzheimer's Disease
Description
Dr. Sun's laboratory is exploring the genetic control of aging in mammals and vertebrates. We are studying the endocrine mechanisms and nutritional factors for their effects on longevity and aging. The physiological role of the somatotropic axis in the control of aging in mammals and vertebrates. The dietary factors on aging and longevity: calorie restriction vs. methionine restriction. Interventions studies of age-related diseases such as Diabetes and Alzheimerís disease.

Selected Publications 
Publication PUBMEDID
Somatotropic signaling: trade-offs between growth, reproductive development, and longevity.
Bartke A, Sun LY, Longo V.
Physiol Rev. 2013 Apr 
23589828 
Longevity is impacted by growth hormone action during early postnatal period.
Sun LY, Fang Y, Patki A, Koopman JJ, Allison DB, Hill CM, Masternak MM, Darcy J, Wang J, McFadden S, Bartke A.
eLife. 2017 Jul 4;6.  
28675141 
Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice.
Sun LY, Spong A, Swindell WR, Fang Y, Hill C, Huber JA, Boehm JD, Westbrook R, Salvatori R, Bartke A.
eLife. 2013 Oct 29 
24175087  
The full list:
https://www.ncbi.nlm.nih.gov/pubmed/?term=sun+liou 
 

Keywords
Aging, longevity and Alzheimer's Disease