| Total Records: 127 |
|
Last Name |
First Name |
Research/Clinical Interest Title |
Keywords |
| AGARWAL |
ANUPAM |
Regulation of heme oxygenase gene expression in kidney and vascular injury |
heme oxygenase, acute kidney injury, transplant nephrology, lymphangiogenesis |
| AMBALAVANAN |
NAMASIVAYAM |
Neonatal lung development and Bronchopulmonary Dysplasia |
Lung, Hypoxia, Hyperoxia, Retinoids, Prediction models |
| ANANTHARAMAIAH |
GATTADAHALLI |
Apolipoproteins, Amphipathic Helices and Atherosclerosis |
|
| BALKOVETZ |
DANIEL |
Epithelial Cell Biology; Epithelial Cell Signal Regulation; Regulation of paracellular transport across epithelial cell tight junctions |
epithelial cells, claudins, tight junctions, E-cadherin, hepatocyte growth factor, ERK, MDCK |
| BALLINGER |
SCOTT |
Environmental cardiology, free radical biology, mitochondrial function, mitochondrial - nuclear interactions |
mitochondria, oxidative stress, evolutionary medicine, cardiovascular disease, cancer, metabolism |
| BAMMAN |
MARCAS |
Exercise as a discovery tool and treatment in regenerative medicine and medical rehabilitation. |
exercise medicine, medical rehabilitation, regenerative medicine, clinical trial, muscle biology |
| BEDWELL |
DAVID |
Translation Termination; Post-Transcriptional Control of Gene Regulation; Suppression of Nonsense Mutations to Treat Genetic Diseases |
Translation Termination, mRNA Turnover, Suppression of Nonsense Mutations to Treat Genetic Diseases |
| BEIERLE CHEN |
ELIZABETH |
(1) Signal transduction pathways in pediatric solid tumors (2) oHSV treatment of pediatric solid tumors |
neuroblastoma, hepatoblastoma, FAK, p53, MYCN, MDM2, oHSV, retinoids, malignant rhabdoid kidney tumor |
| BELLIS |
SUSAN |
Role of glycosylation in tumor progression and metastasis |
tumorigenesis, metastasis, cancer stem cell, cell invasion, apoptosis, tumor immunology, |
| BENVENISTE |
ETTY |
Immune/nervous system interactions |
|
| BEVENSEE |
MARK |
Cellular and Molecular Physiology of Acid-base Transporters and pH Regulation |
acid-base, bicarbonate, transporter, brain, fluorescence dyes, glia , heart, intracellular pH, microelectrodes, neuron, Xenopus oocyte, neuronal firing, kidney, polycystic kidney disease, epithelial sodium channel |
| BHATIA |
RAVI |
|
|
| BHATNAGAR |
SUSHANT |
Identification and characterization of novel factors in insulin secretion in obesity and type 2 diabetes |
Obesity, Type 2 Diabetes, Beta Cell Biology, Insulin Secretion, SNARE Biology, Secreted Proteins, Insulin Granule Trafficking, Tomosyn Proteins, Post-translational Modifications |
| BOLISETTY |
SUBHASHINI |
Mechanisms of injury and repair during Acute Kidney Injury |
Ferritin, iron, heme oxygenase, macrophages, inflammation, acute kidney injury, sepsis |
| BRILES |
DAVID |
Pneumococcal virulence factors; mechanisms of action and use in vaccine |
Streptococcus pneumoniae, virulence, host immunity, vaccines, virulence factors, mechanisms of virulence, vaccine antigens |
| BRITT |
WILLIAM |
Human Herpesviruses, Molecular Virology and Pathogenesis |
cytomegalovirus, perinatal infections, virus assembly |
| BURROWS |
PETER |
B Lymphocyte Development and Function |
B lymphocyte, development, molecular biology |
| CHANG |
CHENBEI |
Growth Factor Signaling and Transcription Regulation in Vertebrate Development |
TGF-beta, neural induction, BMP, ErbB, gastrulation, cell movement |
| CHEN |
YABING |
Gene Regulation and Function in the Pathogenesis of Cardiovascular Disease and Aging |
vascular smooth muscle cells, excellular matrix, vascular calcification, atherosclerosis, diabetes, aging |
| CHESNOKOV |
IGOR |
DNA Replication and Cell Cycle in Eukaryotes |
DNA replication, cytokinesis, Origin Recognition Complex |
| CHOW |
LOUISE |
Human papillomavirus DNA replication and pathogenesis |
HPV infections and cancers |
| COLLAWN |
JAMES |
Role of ion channels in cystic fibrosis |
Cystic Fibrosis; Endocytosis; Protein Trafficking, chymase, heart failure |
| COWELL |
RITA |
Cellular Vulnerability in Development and Aging: Using the Molecular Phenotype of Neurons to Elucidate Mechanisms of Disease and Identify Targets for Intervention |
Transcription, Parkinson Disease, ALS, frontotemporal dementia, movement disorders, Neuroanatomy, Metabolism, Mitochondria, Neurobiology, Mouse models |
| CURCIO |
CHRISTINE |
|
|
| CURTIS |
LISA |
Aging and gender in acute kidney injury |
acute kidney injury, aging, stem cells, heme oxygenase-1, gender, female |
| DATTA |
PRAN |
|
|
| DAY |
JEREMY |
Neurobiology of motivated and learned behaviors |
Epigenetics, addiction, memory, molecular mechanisms, optogenetics |
| DESHANE |
JESSY |
|
|
| DING |
QIANG |
Molecular mechanisms of organ fibrosis |
Signal Transduction; Cell Physiology, Adhesion & Migration Signaling; Molecular Genetics & Disease; Gene Regulation and Expression |
| DOBRUNZ |
LYNN |
Hippocampal Synaptic Transmission and Plasticity, Circuits that Regulate Anxiety, Noninvasive Neuromodulation |
anxiety, Neuropeptide Y, hippocampus |
| FANUCCHI |
MICHELLE |
|
|
| FATHALLAH-SHAYKH |
HASSAN |
Computational Personalized Medicine and Mathematics |
Glioma, Cancer, Clinical Trials, Multiple Sclerosis, Image Segmentation, Motility, Modeling, Dynamical Systems, Chaos, Networks, Circadian Clocks, Ordinary Differential Equations, Partial Differential Equations |
| FAUL |
CHRISTIAN |
The role of endocrine Fibroblast Growth Factors in Chronic Kidney Disease and Diabetes and in associated pathologies. |
chronic kidney disease, uremic cardiomyopathy, diabetic cardiomyopathy, FGF23, FGF21, Klotho, signal transduction |
| FRANK |
STUART |
Growth Hormone Action and GH Receptor Structure and Function |
growth hormone, signaling, prolactin, IGF-1, growth factors |
| GAGGAR |
AMIT |
Proteases in Cystic Fibrotic Lung Disease, Proteases in Lung Transplantation |
proteases, extracellular matrix, neutrophils, inflammation, innate immunity |
| GAMBLE |
KAREN |
NIH funded projects (active): Circadian dysfunction in neurodegenerative disease; The nigral molecular clock and vulnerability to neurodegeneration |
circadian rhythms, biological clocks, shift work, entrainment, suprachiasmatic nucleus |
| GAMLIN |
PAUL |
Studies of the Neural Bases of Vision & Eye Movements |
pupil, vergence, gene therapy, fMRI |
| GARVEY |
W. |
Molecular and physiological pathogenesis of human insulin resistance |
Insulin resistance, obesity, Metabolic Syndrome, Type 2 Diabetes |
| GILBERT |
SHAWN |
|
HIF, angiogenesis, bone, obesity, fracture |
| GRAY |
MICHAEL |
Bacterial responses to oxidative stress |
microbiota, redox, stress, probiotics, reactive chlorine, inflammation |
| GRAY |
MICHELLE |
Pathogenesis of Huntington's Disease |
Huntington's disease, neurodegeneration, neuroscience, astrocytes |
| GROSS |
ALECIA |
GPCR trafficking in neurons and rhodopsin-mediated retinal degenerations |
rhodopsin, autosomal dominant retinitis pigmentosa, GPCR trafficking, rab11, nudC, MKS proteins, NPHP proteins, BBS proteins, retinal degeneration, inflammatory response in retina, cilia, protein trafficking |
| HABEGGER |
KIRK |
FGF21 as mediator of the metabolic actions of glucagon & Duodenal nutrient exclusion enhances glucose metabolism via CNS regulation |
|
| HABLITZ |
JOHN |
Cellular Mechanisms of Neurotransmission |
|
| HARRINGTON |
LAURIE |
Protective and Pathogenic CD4 T Cell Responses |
CD4 T cells, autoimmunity, immunological memory, cytokines |
| HARRIS |
MELISSA |
Gene regulatory networks and transcriptional regulation of stem cell maintenance, stem cells and aging, melanocyte stem cells and hair graying, mouse models of hair graying |
stem cells, aging, gene networks, transcriptional regulation, bioinformatics, melanocytes, gray hair |
| HARTMAN |
JOHN |
Experimental models of gene interaction networks that buffer human disease using cell array phenotyping of yeast gene knockout libraries |
yeast genetics, quantitative high throughput cell array phenotyping (Q-HTCP), gene interaction networks, cellular quiescence, aging, cystic fibrosis, chemotherapy response, systems biology, drug discovery, lab automation |
| HASSAN |
QUAMARUL |
Gene Regulation by Non-coding RNA, Chromatin Remodeling and Modifications |
MicroRNA, Epigenetics, Bone, Tooth, Osteoblast Gene Expression, Odontoblast Gene Regulation |
| HERSKOWITZ |
JEREMY |
Neurobiology of Alzheimer's Disease |
Neurodegeneration, Alzheimer's disease, amyloid, signaling, plasticity, behavior, neuroscience, cell biology |
| HILDRETH |
BLAKE |
Role of macrophages and osteoclasts in bone metastasis and primary bone tumors |
macrophage, osteoclast, breast cancer, primary bone tumor, bone, metastasis |
| HJELMELAND |
ANITA |
Targeting Brain Tumor Initiating Cells and the Tumor Microenvironment |
Brain Tumor, Tumor Microenvironment, Tumor Initiating Cell, Cancer Stem Cell |
| HSU |
HUI-CHEN |
The BXD2 autoimmune mouse model of lupus and erosive arthritis |
BXD2, lupus, arthritis, IL-17, type I IFN, apoptotic cells |
| HU |
HUI |
Transcriptional Regulation of Adaptive Immunity |
Tfh cell differentiation, GC responses, CD8+ T cell quiescence/activation, T cell responses, immune memory, vaccines |
| HUNTER |
CHAD |
Transcriptional control of pancreatic beta cell development and adult islet cell function |
Diabetes, Transcription Factor, Coregulators, Gene Regulation, Organogenesis, Pancreas, Chromatin, Developmental Biology, Endocrinology |
| HYNDMAN |
KELLY |
Novel mechanisms of HDAC1 regulation of collecting duct function. |
nitric oxide, endothelin, collecting duct, histone deacetylase, Aquaporin-2 |
| JAVED |
AMJAD |
Genetic and Molecular Signaling for Cellular Differentiation and Skeletogenesis |
Osteoblast, Bone Development, Gene Regulation, Osteoporosis |
| KADISHA |
INGA |
The role of white matter changes in aging and Alzheimer's disease |
Alzheimer's Disease, Aging, Cognition |
| KANO |
SHINICHI |
Immunology of brain homeostasis and disease |
Neuroimmunology, Glia, Cytokine, Epigenetics, Extracellular vesicles, Schizophrenia |
| KARTHIKEYAN |
MYTHREYE |
Molecular and cellular mechanisms of signaling during metastasis |
ovarian cancer, TGFbeta, BMP, inhibin/activin, betaglycan, cellular signaling, extracellular matrix , cell survival mechanisms |
| KEDISHVILI |
NATALIA |
Discovery and characterization of novel enzymes that regulate the conversion of vitamin A to bioactive retinoic acid |
vitamin A, retinoic acid, oxidoreductases, development, differentiation |
| KIM |
JEONGA |
Cross-talk between inflammation and insulin signaling |
Insulin Resistance, Endothelial Dysfunction, NO, ROS, Polyphenol |
| KLUG |
CHRISTOPHER |
Hematopoietic stem cell biology, acute leukemia, and pancreatic cancer |
|
| KNIGHT |
JOHN |
Oxalate Handling and Synthesis and its Relationship to Health and Disease |
Calcium oxalate kidney stone disease, Oxalobacter formigenes, primary hyperoxaluria |
| KRISHNAMURTHY |
PRASANNA |
Molecular mechanisms of cardiovascular diseases & stem cell-mediated regeneration and repair. |
Myocardial infarction, Heart failure, Stem cells, Cardiovascular regeneration and therapeutics, metabolic diseases, wound healing |
| LAHTI |
ADRIENNE |
Neuroimaging |
psychiatry, schizophrenia, research, lahti |
| LEAVENWORTH |
JIANMEI |
Cancer-Immune cell Crosstalk: Discovery of new targets for cancer immunotherapy |
Immunology, Cancer Immunology, Immunotherapy, Treg, NK cells, glioma |
| LEFKOWITZ |
ELLIOT |
Microbial Genomics and Evolution; Bioinformatics, and Clinical Informatics |
Viruses, Evolution, Genomics, Bioinformatics, Biomedical Informatics |
| LI |
LI |
Mood Disorders, Opioids Dependence |
|
| LU |
RUI |
Epigenetic Mechanisms in Cancer Initiation, Maintenance, and Drug Resistance |
Cancer, Leukemia, Epigenetics, Genomics, Chromatin, Gene regulation, Novel therapeutics |
| LUBIN |
FARAH |
Molecular genetic mechanisms in learning and memory |
Epigenetics, signal transduction, gene transcription, CRISPR-dCas9, neurology, neuroscience, learning and memory, aging, epilepsy, Alzheimer's Disease |
| MARKERT |
JAMES |
Engineering Herpes Simplex Viruses for the Therapy of Cancer |
glioma, gene therapy, brain tumors, herpes simplex, cancer therapy, immunotherapy, anti-angiogenic therapy |
| MATALON |
SADIS |
Free Radical Protection from and Exacerbation of Lung Injury |
Acute Lung Injury, pulmonary edema, pulmonary surfactant, alveolar epithelium, free radicals, nitric oxide, sodium channels |
| MITCHELL |
TANECIA |
The Role of Mitochondria in Immune Cells in Urological Disorders |
Mitochondria, Oxidative Stress, Inflammation, Immune Cells, Kidney Stones, Interstitial Cystitis/Painful Bladder Syndrome |
| MITRA |
KASTURI |
Exploring the significance of mitochondrial structural change in health and disease |
Mitochondria, Cell proliferation, Energetics, Cancer, Stem cells |
| MOUNTZ |
JOHN |
autoimmunity, immune senescence, gene therapy |
type I IFNs, IL-23, germinal centers, marginal zone macrophages, inflammatory macrophages, rheumatoid arthritis, lupus |
| MYERS |
RICHARD |
|
|
| NORIAN |
LYSE |
Understanding the effects of diet and obesity on anti-tumor immunity |
cancer immunology, immunotherapy, obesity, diet, kidney cancer, breast cancer |
| PARANT |
JOHN |
Animal Models of Genomic Instability, p53 Regulation, Cancer and Mitotic Dysfunction |
Zebrafish, Mouse, Li Fraumeni Syndrome, Roberts syndrome, Birth Defects, Tumor Suppressor, Genomic Instability, Aneuploidy, Mitosis, DNA damage, Cancer, and Apoptosis. |
| PARPURA |
VLADIMIR |
The role of glial cells in physiology of nervous system. |
astrocyte, autism spectrum disorder, carbon nanotubes, glial biology, gliomas, enteric glia, exocytosis, glutamate, glial-neuronal signaling, intellectual disability, nanotechnology, neural prosthesis, optogenetics, physiology, pathology |
| PATERSON |
ANDREW |
Role of O-Glycosylation in Gene Regulation, Cell Growth, and Differentiation. |
Transcription factors, gene regulation, proteasome, glycosylation, O-GlcNAc, development, transgenic mice |
| PENG |
JI-BIN |
Calcium transport proteins and their roles in health and disease |
Calcium transport, absorption, reabsorption, hyercalciuria, hypertension, TRPV6, TRPV5, WNK4 |
| POGWIZD |
STEVEN |
|
|
| POPOV |
KIRILL |
Regulation of pyruvate dehydrogenase complex |
|
| POZZO-MILLER |
LUCAS |
Neurotrophins in Synapse Development and Plasticity, Intellectual Disabilities, and Syndromic Autisms |
BDNF, Ca2+, Synapse, Rett Syndrome, Hippocampus, Dendritic Spines, MeCP2, Autism, Intellectual Disability |
| PREVELIGE |
PETER |
Structural Biology of Viral Assembly and Infection |
|
| RAMAN |
CHANDER |
Lymphocyte activation, immunopathogenesis of systemic and neuroimmune autoimmune disease, inflammatory diseases of the skin. |
Autoimmunity, Multiple Sclerosis, Skin inflammatory diseases |
| RAMANADHAM |
SASANKA |
Role of Lipid Mediators in Signal Transduction |
Islets, signal transduction, iPLA2, bone, protease inhibitors |
| ROBERSON |
ERIK |
Neurobiology of Alzheimer's Disease and Frontotemporal Dementia |
Neurodegeneration, Alzheimer's disease, frontotemporal dementia, tau, progranulin, excitability, signaling, plasticity, behavior |
| ROWE |
GLENN |
Exercise-Induced Metabolic Adaptations in Striated Muscle |
striated muscle, mitochondria, transcriptional regulation, metabolism, exercise |
| ROWE |
STEVEN |
Cystic Fibrosis Clinical and Translational Research |
cystic fibrosis, CFTR, nonsense mutations |
| RYAN |
THOMAS |
Stem Cell Therapies in Animal Models of Human Disease |
Sickle cell anemia, thalassemia, embryonic stem cells, hemoglobin, mutagenesis, gene regulation |
| SAMANT |
RAJEEV |
Tumor progression and metastasis of cancer. |
Ribosome Biogenesis, Epithelial-Mesenchymal-Transition, mylti-protein complexes, transcription regulation, nucleolus, protein stability, chaperones, Hest shock proteins |
| SANDERSON |
RALPH |
Molecular Regulation of the Tumor Microenvironment |
tumor, microenvironment, cancer, heparan sulfate, proteoglycan, heparanase, exosomes, metastasis, bone, myeloma, breast cancer, drug resistance |
| SCHWIEBERT |
LISA |
Airway inflammation; lung function; asthma and exercise |
|
| SERRA |
ROSA |
Mechanism of TGF-ß Action in Developmental and Disease Processes |
developmental biology, bone, cartilage, teeth, intervertebral disc, osteoarthrits, skeletal disease |
| SETHU |
PALANIAPPAN |
|
cardiac and vascular models, mechanical stresses, cardiac regeneration, normal and disturbed flow |
| SHACKA |
JOHN |
Targeting the Autophagy-Lysosome Pathway for Therapeutic Benefit in Parkinson's Disease |
Autophagy; Lysosome; Parkinson's; Synuclein; Alpha-Galactosidase |
| SHALEV |
ANATH |
|
|
| SHEVDE-SAMANT |
LALITA |
Investigating molecular signaling mechanisms that present as fundamental aberrations in tumor cells or their immune microenvironment |
Tumor progression, metastasis, innate and adaptive immune microenvironment, signaling, cancer stem cells, chemoresistance, metabolism, osteolysis, Merlin, Hedgehog pathway, Wnt pathway |
| SHRESTHA |
SADEEP |
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