Total Records: 127 |
Last Name |
First Name |
Research/Clinical Interest Title |
Keywords |
WHITE |
CHARLES |
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DATTA |
PRAN |
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SMITH |
DANIEL |
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FANUCCHI |
MICHELLE |
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SETHU |
PALANIAPPAN |
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cardiac and vascular models, mechanical stresses, cardiac regeneration, normal and disturbed flow |
BHATIA |
RAVI |
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MYERS |
RICHARD |
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WHITLEY |
RICHARD |
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Herpes simplex virus; varicella zoster virus; drug discovery; cytomegalovirus |
GILBERT |
SHAWN |
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HIF, angiogenesis, bone, obesity, fracture |
SHALEV |
ANATH |
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POGWIZD |
STEVEN |
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SHRESTHA |
SADEEP |
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DESHANE |
JESSY |
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BEIERLE CHEN |
ELIZABETH |
(1) Signal transduction pathways in pediatric solid tumors (2) oHSV treatment of pediatric solid tumors |
neuroblastoma, hepatoblastoma, FAK, p53, MYCN, MDM2, oHSV, retinoids, malignant rhabdoid kidney tumor |
CURTIS |
LISA |
Aging and gender in acute kidney injury |
acute kidney injury, aging, stem cells, heme oxygenase-1, gender, female |
SUN |
LIOU |
Aging, longevity and Alzheimer's Disease |
Aging, longevity and Alzheimer's Disease |
PARANT |
JOHN |
Animal Models of Genomic Instability, p53 Regulation, Cancer and Mitotic Dysfunction |
Zebrafish, Mouse, Li Fraumeni Syndrome, Roberts syndrome, Birth Defects, Tumor Suppressor, Genomic Instability, Aneuploidy, Mitosis, DNA damage, Cancer, and Apoptosis. |
ANANTHARAMAIAH |
GATTADAHALLI |
Apolipoproteins, Amphipathic Helices and Atherosclerosis |
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MOUNTZ |
JOHN |
autoimmunity, immune senescence, gene therapy |
type I IFNs, IL-23, germinal centers, marginal zone macrophages, inflammatory macrophages, rheumatoid arthritis, lupus |
BURROWS |
PETER |
B Lymphocyte Development and Function |
B lymphocyte, development, molecular biology |
GRAY |
MICHAEL |
Bacterial responses to oxidative stress |
microbiota, redox, stress, probiotics, reactive chlorine, inflammation |
PENG |
JI-BIN |
Calcium transport proteins and their roles in health and disease |
Calcium transport, absorption, reabsorption, hyercalciuria, hypertension, TRPV6, TRPV5, WNK4 |
LEAVENWORTH |
JIANMEI |
Cancer-Immune cell Crosstalk: Discovery of new targets for cancer immunotherapy |
Immunology, Cancer Immunology, Immunotherapy, Treg, NK cells, glioma |
WADICHE |
JACQUES |
Cellular and molecular basis of synaptic transmission and neuronal organization of microcircuits |
glutamate transport, synaptic transmission, cerebellum |
BEVENSEE |
MARK |
Cellular and Molecular Physiology of Acid-base Transporters and pH Regulation |
acid-base, bicarbonate, transporter, brain, fluorescence dyes, glia , heart, intracellular pH, microelectrodes, neuron, Xenopus oocyte, neuronal firing, kidney, polycystic kidney disease, epithelial sodium channel |
HABLITZ |
JOHN |
Cellular Mechanisms of Neurotransmission |
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COWELL |
RITA |
Cellular Vulnerability in Development and Aging: Using the Molecular Phenotype of Neurons to Elucidate Mechanisms of Disease and Identify Targets for Intervention |
Transcription, Parkinson Disease, ALS, frontotemporal dementia, movement disorders, Neuroanatomy, Metabolism, Mitochondria, Neurobiology, Mouse models |
YODER |
BRADLEY |
Cilia Signaling and Dysfunction in Development and Disease |
Cilia, cystic kidney diseases, obesity, signal transduction, cell fate determination and embryonic patterning, birth defects, mouse and C. elegans models. |
VOLPICELLI-DALEY |
LAURA |
Cognitive impairments in Parkinson's disease and Lewy body dementias |
Parkinson's disease, Lewy body dementias, synuclein, tau, glucocerebrosidase, cell biology of the neuron, neurodegeneration |
VISSCHER |
KRISTINA |
Cognitive Neuroscience |
attention, memory, older adults, aging, training, ongoing activity, EEG, fMRI, human neuroscience |
FATHALLAH-SHAYKH |
HASSAN |
Computational Personalized Medicine and Mathematics |
Glioma, Cancer, Clinical Trials, Multiple Sclerosis, Image Segmentation, Motility, Modeling, Dynamical Systems, Chaos, Networks, Circadian Clocks, Ordinary Differential Equations, Partial Differential Equations |
KIM |
JEONGA |
Cross-talk between inflammation and insulin signaling |
Insulin Resistance, Endothelial Dysfunction, NO, ROS, Polyphenol |
ROWE |
STEVEN |
Cystic Fibrosis Clinical and Translational Research |
cystic fibrosis, CFTR, nonsense mutations |
KEDISHVILI |
NATALIA |
Discovery and characterization of novel enzymes that regulate the conversion of vitamin A to bioactive retinoic acid |
vitamin A, retinoic acid, oxidoreductases, development, differentiation |
CHESNOKOV |
IGOR |
DNA Replication and Cell Cycle in Eukaryotes |
DNA replication, cytokinesis, Origin Recognition Complex |
MARKERT |
JAMES |
Engineering Herpes Simplex Viruses for the Therapy of Cancer |
glioma, gene therapy, brain tumors, herpes simplex, cancer therapy, immunotherapy, anti-angiogenic therapy |
BALLINGER |
SCOTT |
Environmental cardiology, free radical biology, mitochondrial function, mitochondrial - nuclear interactions |
mitochondria, oxidative stress, evolutionary medicine, cardiovascular disease, cancer, metabolism |
LU |
RUI |
Epigenetic Mechanisms in Cancer Initiation, Maintenance, and Drug Resistance |
Cancer, Leukemia, Epigenetics, Genomics, Chromatin, Gene regulation, Novel therapeutics |
BALKOVETZ |
DANIEL |
Epithelial Cell Biology; Epithelial Cell Signal Regulation; Regulation of paracellular transport across epithelial cell tight junctions |
epithelial cells, claudins, tight junctions, E-cadherin, hepatocyte growth factor, ERK, MDCK |
BAMMAN |
MARCAS |
Exercise as a discovery tool and treatment in regenerative medicine and medical rehabilitation. |
exercise medicine, medical rehabilitation, regenerative medicine, clinical trial, muscle biology |
ROWE |
GLENN |
Exercise-Induced Metabolic Adaptations in Striated Muscle |
striated muscle, mitochondria, transcriptional regulation, metabolism, exercise |
HARTMAN |
JOHN |
Experimental models of gene interaction networks that buffer human disease using cell array phenotyping of yeast gene knockout libraries |
yeast genetics, quantitative high throughput cell array phenotyping (Q-HTCP), gene interaction networks, cellular quiescence, aging, cystic fibrosis, chemotherapy response, systems biology, drug discovery, lab automation |
MITRA |
KASTURI |
Exploring the significance of mitochondrial structural change in health and disease |
Mitochondria, Cell proliferation, Energetics, Cancer, Stem cells |
HABEGGER |
KIRK |
FGF21 as mediator of the metabolic actions of glucagon & Duodenal nutrient exclusion enhances glucose metabolism via CNS regulation |
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MATALON |
SADIS |
Free Radical Protection from and Exacerbation of Lung Injury |
Acute Lung Injury, pulmonary edema, pulmonary surfactant, alveolar epithelium, free radicals, nitric oxide, sodium channels |
CHEN |
YABING |
Gene Regulation and Function in the Pathogenesis of Cardiovascular Disease and Aging |
vascular smooth muscle cells, excellular matrix, vascular calcification, atherosclerosis, diabetes, aging |
HASSAN |
QUAMARUL |
Gene Regulation by Non-coding RNA, Chromatin Remodeling and Modifications |
MicroRNA, Epigenetics, Bone, Tooth, Osteoblast Gene Expression, Odontoblast Gene Regulation |
HARRIS |
MELISSA |
Gene regulatory networks and transcriptional regulation of stem cell maintenance, stem cells and aging, melanocyte stem cells and hair graying, mouse models of hair graying |
stem cells, aging, gene networks, transcriptional regulation, bioinformatics, melanocytes, gray hair |
JAVED |
AMJAD |
Genetic and Molecular Signaling for Cellular Differentiation and Skeletogenesis |
Osteoblast, Bone Development, Gene Regulation, Osteoporosis |
WENDE |
ADAM |
Glucose-mediated remodeling of cardiac DNA methylation |
Diabetes, Hypertension, Exercise, Mitochondria, Metabolism, Glucose, Epigenetics, Gene expression, transcription, O-GlcNAc, protein modifications, DNA methylation, Histone modification, GLUT4, PDK2, PDK4 |
GROSS |
ALECIA |
GPCR trafficking in neurons and rhodopsin-mediated retinal degenerations |
rhodopsin, autosomal dominant retinitis pigmentosa, GPCR trafficking, rab11, nudC, MKS proteins, NPHP proteins, BBS proteins, retinal degeneration, inflammatory response in retina, cilia, protein trafficking |
CHANG |
CHENBEI |
Growth Factor Signaling and Transcription Regulation in Vertebrate Development |
TGF-beta, neural induction, BMP, ErbB, gastrulation, cell movement |
FRANK |
STUART |
Growth Hormone Action and GH Receptor Structure and Function |
growth hormone, signaling, prolactin, IGF-1, growth factors |
KLUG |
CHRISTOPHER |
Hematopoietic stem cell biology, acute leukemia, and pancreatic cancer |
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DOBRUNZ |
LYNN |
Hippocampal Synaptic Transmission and Plasticity, Circuits that Regulate Anxiety, Noninvasive Neuromodulation |
anxiety, Neuropeptide Y, hippocampus |
BRITT |
WILLIAM |
Human Herpesviruses, Molecular Virology and Pathogenesis |
cytomegalovirus, perinatal infections, virus assembly |
CHOW |
LOUISE |
Human papillomavirus DNA replication and pathogenesis |
HPV infections and cancers |
BHATNAGAR |
SUSHANT |
Identification and characterization of novel factors in insulin secretion in obesity and type 2 diabetes |
Obesity, Type 2 Diabetes, Beta Cell Biology, Insulin Secretion, SNARE Biology, Secreted Proteins, Insulin Granule Trafficking, Tomosyn Proteins, Post-translational Modifications |
BENVENISTE |
ETTY |
Immune/nervous system interactions |
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KANO |
SHINICHI |
Immunology of brain homeostasis and disease |
Neuroimmunology, Glia, Cytokine, Epigenetics, Extracellular vesicles, Schizophrenia |
SZALAI |
ALEXANDER |
Inflammation, innate immunity, and the acute phase proteins in health and disease |
SLE, EAE, CRP, complement, innate immunity, FcgR, SAP, acute phase proteins, heart and blood vessel disease |
YUSUF |
NABIHA |
Innate immune mechanisms in tumor development |
toll like receptors, type I interferons, immune system, cancer, T-cells |
SHEVDE-SAMANT |
LALITA |
Investigating molecular signaling mechanisms that present as fundamental aberrations in tumor cells or their immune microenvironment |
Tumor progression, metastasis, innate and adaptive immune microenvironment, signaling, cancer stem cells, chemoresistance, metabolism, osteolysis, Merlin, Hedgehog pathway, Wnt pathway |
XU |
JIA |
Investigating the mechanisms by which oncogenic signaling pathways impact tumor cell division, growth and metastasis |
AURKB, PI3K/AKT/PTEN pathway, Mitosis, Cancer Biology, Cancer signaling pathway, PROTAC, AAV gene therapy |
RAMAN |
CHANDER |
Lymphocyte activation, immunopathogenesis of systemic and neuroimmune autoimmune disease, inflammatory diseases of the skin. |
Autoimmunity, Multiple Sclerosis, Skin inflammatory diseases |
SERRA |
ROSA |
Mechanism of TGF-ß Action in Developmental and Disease Processes |
developmental biology, bone, cartilage, teeth, intervertebral disc, osteoarthrits, skeletal disease |
ZHANG |
JIANHUA |
Mechanisms and regulation of autophagy-lysosomal pathway in health and diseases |
Autophagy, Parkinson's Disease, Alzheimer's disease, heart disease, lysosomes, mitochondria, redox signaling |
BOLISETTY |
SUBHASHINI |
Mechanisms of injury and repair during Acute Kidney Injury |
Ferritin, iron, heme oxygenase, macrophages, inflammation, acute kidney injury, sepsis |
SZTUL |
ELIZABETH |
Membrane Traffic; Protein Degradation |
Cystic fibrosis, membrane traffic, degradation, quality control |
LEFKOWITZ |
ELLIOT |
Microbial Genomics and Evolution; Bioinformatics, and Clinical Informatics |
Viruses, Evolution, Genomics, Bioinformatics, Biomedical Informatics |
SINGH |
KESHAV |
Mitochondrial Metabolism, Mitochondria-to-Nucleus Retrograde Cross Talk, Oxidative Stress, Genomic Instability and Its Role in Tumor Progression and Metastasis |
mitochondria, genomic instability, cancer, breast cancer, prostate, arsenic, oxidative stress, metabolism, tumor progression, tumor metastasis |
KARTHIKEYAN |
MYTHREYE |
Molecular and cellular mechanisms of signaling during metastasis |
ovarian cancer, TGFbeta, BMP, inhibin/activin, betaglycan, cellular signaling, extracellular matrix , cell survival mechanisms |
GARVEY |
W. |
Molecular and physiological pathogenesis of human insulin resistance |
Insulin resistance, obesity, Metabolic Syndrome, Type 2 Diabetes |
LUBIN |
FARAH |
Molecular genetic mechanisms in learning and memory |
Epigenetics, signal transduction, gene transcription, CRISPR-dCas9, neurology, neuroscience, learning and memory, aging, epilepsy, Alzheimer's Disease |
KRISHNAMURTHY |
PRASANNA |
Molecular mechanisms of cardiovascular diseases & stem cell-mediated regeneration and repair. |
Myocardial infarction, Heart failure, Stem cells, Cardiovascular regeneration and therapeutics, metabolic diseases, wound healing |
DING |
QIANG |
Molecular mechanisms of organ fibrosis |
Signal Transduction; Cell Physiology, Adhesion & Migration Signaling; Molecular Genetics & Disease; Gene Regulation and Expression |
WEINMANN |
AMY |
Molecular mechanisms that regulate T cell differentiation programs |
T cell differentiation, epigenetics, metabolism, chromatin, gene programming, development |
SANDERSON |
RALPH |
Molecular Regulation of the Tumor Microenvironment |
tumor, microenvironment, cancer, heparan sulfate, proteoglycan, heparanase, exosomes, metastasis, bone, myeloma, breast cancer, drug resistance |
LI |
LI |
Mood Disorders, Opioids Dependence |
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WILSON |
SCOTT |
Mouse Models of Neurodegeneration |
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AMBALAVANAN |
NAMASIVAYAM |
Neonatal lung development and Bronchopulmonary Dysplasia |
Lung, Hypoxia, Hyperoxia, Retinoids, Prediction models |
HERSKOWITZ |
JEREMY |
Neurobiology of Alzheimer's Disease |
Neurodegeneration, Alzheimer's disease, amyloid, signaling, plasticity, behavior, neuroscience, cell biology |
ROBERSON |
ERIK |
Neurobiology of Alzheimer's Disease and Frontotemporal Dementia |
Neurodegeneration, Alzheimer's disease, frontotemporal dementia, tau, progranulin, excitability, signaling, plasticity, behavior |
DAY |
JEREMY |
Neurobiology of motivated and learned behaviors |
Epigenetics, addiction, memory, molecular mechanisms, optogenetics |
LAHTI |
ADRIENNE |
Neuroimaging |
psychiatry, schizophrenia, research, lahti |
WYSS |
JAMES |
Neuroplasticity in aging and neuro cardiovascular control |
Alzheimers, hypertension, neuronal plasticity, behavior, blood pressure, botanicals, STEM education |
GORBATYUK |
MARINA |
Neuroprotection for animal models of retinal degenration |
Retinal Degeneration, Unfolded Protein Response, Neuroprotection |
POZZO-MILLER |
LUCAS |
Neurotrophins in Synapse Development and Plasticity, Intellectual Disabilities, and Syndromic Autisms |
BDNF, Ca2+, Synapse, Rett Syndrome, Hippocampus, Dendritic Spines, MeCP2, Autism, Intellectual Disability |
GAMBLE |
KAREN |
NIH funded projects (active): Circadian dysfunction in neurodegenerative disease; The nigral molecular clock and vulnerability to neurodegeneration |
circadian rhythms, biological clocks, shift work, entrainment, suprachiasmatic nucleus |
HYNDMAN |
KELLY |
Novel mechanisms of HDAC1 regulation of collecting duct function. |
nitric oxide, endothelin, collecting duct, histone deacetylase, Aquaporin-2 |
WICK |
TIMOTHY |
Orthopaedic and Cardiovascular Tissue Engineering and Regenerative Medicine |
Tissue Engineering, Regenerative Medicine, Cartilage, Bone, Blood Vessel, Bioreactor Technology, Osteoarthritis |
KNIGHT |
JOHN |
Oxalate Handling and Synthesis and its Relationship to Health and Disease |
Calcium oxalate kidney stone disease, Oxalobacter formigenes, primary hyperoxaluria |
GRAY |
MICHELLE |
Pathogenesis of Huntington's Disease |
Huntington's disease, neurodegeneration, neuroscience, astrocytes |
BRILES |
DAVID |
Pneumococcal virulence factors; mechanisms of action and use in vaccine |
Streptococcus pneumoniae, virulence, host immunity, vaccines, virulence factors, mechanisms of virulence, vaccine antigens |
GAGGAR |
AMIT |
Proteases in Cystic Fibrotic Lung Disease, Proteases in Lung Transplantation |
proteases, extracellular matrix, neutrophils, inflammation, innate immunity |
HARRINGTON |
LAURIE |
Protective and Pathogenic CD4 T Cell Responses |
CD4 T cells, autoimmunity, immunological memory, cytokines |
AGARWAL |
ANUPAM |
Regulation of heme oxygenase gene expression in kidney and vascular injury |
heme oxygenase, acute kidney injury, transplant nephrology, lymphangiogenesis |
POPOV |
KIRILL |
Regulation of pyruvate dehydrogenase complex |
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BELLIS |
SUSAN |
Role of glycosylation in tumor progression and metastasis |
tumorigenesis, metastasis, cancer stem cell, cell invasion, apoptosis, tumor immunology, |
COLLAWN |
JAMES |
Role of ion channels in cystic fibrosis |
Cystic Fibrosis; Endocytosis; Protein Trafficking, chymase, heart failure |
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