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Faculty Detail    
Name HARRISON KIM
  
Campus Address VH G082 Zip 0019
Phone  (205) 996-4088
E-mail  hyunki@uab.edu
Other websites http://medicine.uab.edu/radiology/67757/
     

Education
Undergraduate  Sung Kyun Kwan University    1997  B.S. 
Graduate  University of Arizona    2004  Ph.D. 
Graduate  University of Alabama at Birmingham    2012  M.B.A. 


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Radiology Chair Office  Radiology Chair Office Professor
Secondary  Biomedical Engineering  Biomedical Engineering Assistant Professor
Center  Comprehensive Cancer Center  Comprehensive Cancer Center Professor
Center  Ctr for Clinical & Translational Sci  Ctr for Clinical & Translational Sci Professor
Center  Cystic Fibrosis Research Center  Cystic Fibrosis Research Center Professor

Biographical Sketch 
AWARDS/HONORS: 1. COVER: Medical Physics, vol. 33, No. 2, 2006. Figure from the research article “SemiSPECT: A small-animal single-photon emission computed tomography (SPECT) imager based on eight cadmium zinc telluride (CZT) detector arrays,” was chosen as cover art. 2. Travel Scholarship Award, Institute of Molecular Imaging (IMI) session, The Academy of Molecular Imaging Annual Conference, Orlando, FL, March 25-29, 2006. 3. Top Drug Development Abstract Award for a Young Investigator, Society of Non-Invasive Imaging in Drug Development (SNIDD) session, The Academy of Molecular Imaging Annual Conference, Orlando, FL, March 25-29, 2006. 4. University of Alabama Health Services Foundation (UAHSF) General Endowment Fund (GEF) Scholar Award, Birmingham, AL, September 20, 2006. 5. Associate editor of Journal Medical Physics, Issue 4, 2007. 6. Radiology Research Initiative Pilot Award, Department of Radiology, School of Medicine, University of Alabama, Birmingham, AL, January 19, 2007. 7. Sylvia Sorkin Greenfield Award for the best paper published in Medical Physics during 2006, 49th Annual Meeting of American Association of Physicists in Medicine (AAPM), Minneapolis, MN, July 22-26, 2007. 8. John R. Durant Award for Excellence in Cancer Research, Third Place in Junior Faculty Category, 11th Comprehensive Cancer Center Research Retreat at UAB, Birmingham, AL, October 29, 2007. 9. Radiology Research Initiative Pilot Award, Department of Radiology, School of Medicine, University of Alabama, Birmingham, AL, January 22, 2008. 10. American Association Cancer Research-Pancreatic Cancer Action Network Career Development Award for Pancreatic Cancer Research, American Association for Cancer Research 99th Annual Meeting, San Diego, CA, April 15, 2008. 11. Junior Faculty Development Grant Award, NCI CA13148-35 UAB Comprehensive Cancer Center, University of Alabama, Birmingham, AL, June 1, 2010. 12. Radiology Research Initiative Pilot Award, Department of Radiology, School of Medicine, University of Alabama, Birmingham, AL, June 29, 2011. 13. Molecular Imaging Development Shared Award, School of Medicine, UAB, August 21, 2011. 14. John R. Durant Award for Excellence in Cancer Research, Second Place in Junior Faculty Category, 14th Comprehensive Cancer Center Research Retreat at UAB, Birmingham, AL, October 25, 2011. 15. Selected for membership in Beta Gamma Sigma, the international honor society for collegiate schools of business, in recognition of high scholastic achievement, May 4, 2012. 16. Radiology Research Initiative Pilot Award, Department of Radiology, School of Medicine, University of Alabama, Birmingham, AL, September 8, 2013. MAJOR LECTURES AND VISITING PROFESSORSHIPS: 1. Special Topics Course Course title: Introduction to Medical Imaging Students: Medical students Student Learning Objectives: To understand the basic principles of medical imaging modalities and their translational applications. Teaching evaluation: Rated 4.7/5 (5=excellent) for the last 3 courses. 2. BME/ECE 443/543 Course title: Medical Image Processing Students: Senior undergraduate (or graduate) students in the department of Biomedical Engineering and Electrical Engineering. Student Learning Objectives: To develop a mathematical understanding of post-processing methods used for medical images and to learn quantitative techniques used to analyze multi-modal medical images. Teaching evaluation: Rated 4.6/5 (5=excellent) for the spring semester 2012 and 2013. GRANT SUPPORT: 1. 2P30CA013148 (Co-investigator) 04/01/11-03/31/16 NIH $625,000 (direct cost) Comprehensive Cancer Center Core Support Grant. Small animal imaging shared facility. To facilitate small animal imaging in cancer models, including MRI/MRS, PET/CT, SPECT/CT, bioluminescence, fluorescence, and high frequency ultrasound. 2. Komen Promise Grant (Co-investigator) 5/01/09-4/31/14 Susan G. Komen for the Cure Research Program $1,190,000 (direct cost) Targeting Death Receptors for the Treatment of Triple Negative Breast Cancer The major goal of this project is to evaluate anti-DR5 antibody, CS1008, in triple-negative breast cancer patients. 3. 5R01CA142637-03 (Co-investigator) 03/01/10 – 02/28/15 NIH $265,000/yr CD147 as a novel target in head and neck cancer These studies are designed to determine if CD147 will serve as a novel target for therapy of head and neck cancer. 4. Radiology Research Initiative Pilot Grant Award (PI) 9/08/13 - 9/07/15 Radiology, UAB $20,000 (direct cost) Title: “Dual combination therapy with vismodegib and gemcitabine for pancreatic cancer” The major goal of this project is to validate the differential therapeutic efficacy of vismodegib combined with gemcitabine for pancreatic cancer according to tumor vascularity. BIBLIOGRAPHY: MANUSCRIPTS: Manuscripts already published 1. Furenlid L. R., Wilson D. W., Chen Y., Kim H., Pietraski P. J., Crawford M. J., and Barrett H. H., “FASTSPECT II: A Second-Generation High-Resolution Dynamic SPECT Imager,” IEEE Transactions on Nuclear Science, vol. 51, pp. 631-635, 2004. 2. Kim H., Furenlid L. R. Crawford M. J., Wilson D. W., Barber H. B., Peterson T. E., Hunter W. C. J., Liu Z. Woolfenden J. M. and Barrett H. H., “SemiSPECT: A small-animal single-photon emission computed tomography (SPECT) imager based on eight cadminum zinc telluride (CZT) detector arrays,” Medical Physics, vol. 33, No. 2, pp. 465-475, 2006 (selected for cover art). 3. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “High resolution single-photon emission computed tomography and x-ray computed tomography Imaging of Tc-99m-labeled anti-DR5 antibody in breast tumor xenografts,” Molecular Cancer Therapeutics, vol. 6, pp. 866-875, 2007. 4. Cowey S., Szafran A. A., Kappes J., Zinn K. R. Siegal G. P. Desmond R. A., Kim H., Evans L., Hardy R. W., “Breast cancer metastasis to bone: Evaluation of bioluminescent imaging and microSPECT/CT for detecting bone metastasis in immunodeficient mice,” Clinical and Experimental Metastasis, vol. 24, pp. 389-401, 2007. 5. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “Single-photon emission computed tomography imaging with a humanized, apoptosis-inducing antibody targeting human death receptor 5 in pancreas and breast tumor xenografts.” Cancer biology and therapy, vol. 6, pp. 1396-1402, 2007 (highlighted article in this issue). 6. Oliver P. G., LoBuglio A. F., Zinn K. R., Kim H., Nan L., Zhou T., Wang W., Buchsbaum D. J., “Treatment of human colon cancer xenografts with TRA-8 anti-death receptor 5 antibody alone or in combination with CPT-11.” Clinical Cancer Research, vol. 14, pp. 2180-2189, 2008. PMCID: PMC2676875 7. Kim H., Morgan D. E., Zeng H., Grizzle W. E., Warram J. M., Stockard C. R., Wang D., Zinn K. R., “Breast Tumor Xenografts: Diffusion-Weighted MR Imaging to Assess Early Therapy with Novel Apoptosis-Inducing Anti-DR5 Antibody,” Radiology, vol. 248, pp. 844-851, 2008. PMCID: PMC2657851 8. Kim H.*, Morgan D. E., Buchsbaum D. J., Zeng H., Grizzle W. E., Warram J. M., Stockard C. R., McNally L. R., Long J. W., Forero-Torres A., Zinn K. R., “Early Therapy Evaluation of Combined Anti-DR5 Antibody and Gemcitabine in Orthotopic Pancreatic Tumor Xenografts by Diffusion-Weighted Magnetic Resonance Imaging,” Cancer Research, vol. 68, pp. 8369-8376, 2008. PMCID: PMC2597015 9. Beck B. H., Kim H. G., Kim H., Samuel S., Liu Z., Shrestha R., Haines H., Zinn K., Lopez R. D., “Adoptively transferred ex vivo expanded gammadelta-T cells mediate in vivo antitumor activity in preclinical mouse models of breast cancer,” Breast Cancer Res Treat, vol. 122, pp. 135-44, 2010. Epub: 18 September 2009. PMCID: PMC2883655 10. Kim H.*, Folks K. D., Guo L., Stockard C. R., Grizzle W. E., Fineberg N., George J. F., Zinn K. R. “DCE-MRI detects early vascular response in breast tumor xenografts following anti-DR5 therapy.” Molecular Imaging and Biology, vol. 13, pp. 94-103, 2011. Epub: 10 April 2010. 11. Kim H., Chen J., Zinn K. R., Hubbard W. J., Fineberg N. S., Chaudry I. H. “Single Photon Emission Computed Tomography Demonstrated Efficacy of 17β-estradiol Therapy in Male Rats following Trauma-Hemorrhage and Extended Hypotension.” J Trauma, vol. 69, pp. 1266-1273, 2010. Epub: 21 June 2010. 12. Kim H.*, Folks K. D., Guo L., Sellers J. C., Fineberg N. S., Stockard C. R., Grizzle W. E., Buchsbaum D. J., Morgan D. E., George J. F., Zinn K. R. “Early Therapy Evaluation of Combined Anti-EGFR Antibody and Irinotecan in Orthotopic Pancreatic Tumor Xenografts by Dynamic Contrast-Enhanced Magnetic Resonance Imaging.” Molecular Imaging, vol. 10, pp. 153-167, 2011. 13. Shah N., Zhai G., Knowles J. A., Stockard, C. R., Grizzle W. E., Fineberg N., Zhou T., Zinn K. R., Rosenthal E. L., Kim H.* “18F-FDG PET/CT Imaging Detects Therapy Efficacy of Anti-EMMPRIN Antibody and Gemcitabine in Orthotopic Pancreatic Tumor Xenografts.” Molecular Imaging and Biology, vol. 14, pp 237-244, 2012. Epub: 15 April 2011. PMCID: PMC3594775 14. Kim H.*, Zhai G., Liu Z., Samuel S., Shah N., Helman E. E., Knowles J. A., Stockard, C. R., Fineberg N. S., Grizzle W. E., Zhou T., Zinn K. R., Rosenthal E. L., “Extracelluar matrix metalloproteinase as a novel target for pancreatic cancer therapy.” Anti-cancer drugs, vol. 22, pp. 864-874, 2011 (highlighted in Extracellular Matrix News on July 14th, 2011). PMCID: PMC3587034 15. Oliver P. G., LoBuglio A. F., Zhou T., Forero A., Kim H., Zinn K. R., Zhai G., Li Y., Lee C. H., Buchsbaum D. J. “Effect of anti-DR5 and chemotherapy on basal-like breast cancer.” Breast Cancer Research and Treatment, vol. 133, pp. 417-426, 2012. PMCID: PMC3613128 16. Kim H.*, Zhai G., Samuel S. L., Rigell C. J., Umphrey H. R., Rana S., Stockard C. R., Fineberg N. S., Zinn K. R. “Dual combination therapy targeting DR5 and EMMPRIN in pancreatic adenocarcinoma” Molecular Cancer Therapeutics, vol. 11, pp. 405-415, 2012. PMCID: PMC3277644 17. Zhai G., Grubbs C. J., Stockard C. R., Umphrey H. R., Beasley T. M. Kim H.*, “Diffusion Weighted Imaging Evaluated the Early Therapy Effect of Tamoxifen in an MNU-Induced Mammary Cancer Rat Model”, Plos One, vol. 8, pp. 1-7, 2013. PMID: 23700476 18. Kim H.*, Rigell C. J., Zhai G., Lee S. K., Samuel S. L., Martin A., Umphrey H. R., Stockard C. R., Beasley T. M., Buchsbaum D. J., Li L. S., Boothman D. A., Zinn K. R., “Antagonistic effects of anti-EMMPRIN antibody when combined with chemotherapy against hypovascular pancreatic cancers”, Molecular Imaging and Biology, vol. 16, pp. 85-94, 2014. PMID: 23836505 19. Zhai G., Kim H.*, Samuel S. L., Saver D. B., Whitworth L., Zinn K. R., “Early therapy assessment of combined anti-DR5 antibody and carboplatin in triple-negative breast cancer xenografts in mice using diffusion-weighted imaging and 1H MR spectroscopy”, Journal of Magnetic Resonance Imaging, Epub: 22 Oct 2013. PMID: 24151215 20. Kim H.*, Arnoletti P. J., Christein J., Heslin M. J., Posey J. A., Pednekar A., Beasley T. M., Morgan D. E., “Pancreatic Adenocarcinoma: A Pilot Study of Quantitative Perfusion and Diffusion Weighted Breath-hold Magnetic Resonance Imaging.” Abdominal Imaging, Epub: 19 Feb 2014. PMID: 24549880 * Asterisk represents corresponding authorship. Accepted manuscript 1. Kim H.*, Keene K. S., Sarver D. B., Lee K. S., Beasley T. M., Morgan D. E., Posey J. A., “Quantitative perfusion and diffusion weighted magnetic resonance imaging of abdominal cancers treated with multikinase inhibitors: a pilot study.” Gastrointestinal Cancer Research, 2014. Other Publications (letters to the author, book reviews, etc.) 1. Kim H., Furenlid L. R. Crawford M. J., Wilson D. W., Barber H. B., Peterson T. E., Hunter W. C. J., Liu Z. Woolfenden J. M. and Barrett H. H., “A Novel Small-Animal SPECT System, SemiSPECT, incorporating Eight CZT Pixellated Detectors,” Academy of Molecular Imaging, AMI news, Spring 2006, pp. 2-3. BOOKS: Books and Book Chapters 1. Furenlid L. R., Chen Yi-Chun, and Kim H., “SPECT Imager Design and Data-Acquisition Systems”. In Kupinski M. A. and Barrett H. H., eds., Small-Animal SPECT Imaging. New York: Springer Science+Business Media, Inc., 2005:115-138. Published abstracts 1. Kim H. “Development and Evaluation of SemiSPECT, a Small-Animal Imager Based on Eight CdZnTe Pixel Detectors,” Molecular Imaging and Biology, vol. 6, no. 79, pp 90, 2004. 2. L. R. Furenlid, Y. Chen, D. W. Wilson, H. Kim, H. H. Barrett, “Small animal imaging with FASTSPECT II,” Molecular Imaging and Biology, vol. 6, no. 5, pp 70, 2004. 3. H. Kim, L. R. Furenlid, M. J. Crawford, D. W. Wilson, B. H. Barber, W. C. J. Hunter, H. H. Barrett, “Small-animal imaging with SemiSPECT,” Molecular Imaging and Biology, vol. 7, no. 224, pp 139, 2005. 4. L. R. Furenlid, H. Kim, D. W. Wilson, Y. Chen, Z. Liu, G. D. Stevenson, B. H. Barber, H. H. Barrett, J. M. Woolfenden, “Preliminary comparison of small-animal SPECT systems based on scintillators and pixellated cadmium zinc telluride arrays,” Journal of Nuclear Medicine, vol. 46, no. 490, pp 170, 2005. 5. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “SPECT/CT imaging of breast and pancreatic tumors with Tc-99m-labeled hTRA-8, a humanized anti-DR5 antibody for cancer therapy,” Clinical Cancer Research, vol. 11, no. 24, part 2, pp 9128s, 2005. 6. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “In vivo imaging of breast cancer xenografts with Tc-99m-labeled mTRA-8, an apoptosis-inducing monomeric antibody targeting DR5,” Clinical Cancer Research, vol. 11, no. 24, part 2, pp 9101s, 2005. 7. Wang D., Kim H., Zinn K. R., “A quantification method of SPECT/CT data for analyzing drug distributions in tumors,” Molecular Imaging and Biology, vol. 8, no. 2, pp 108, 2006. 8. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “Characterization of Tc-99m-labeled anti-DR5 antibody (mTRA-8) by in vitro analyses and in vivo imaging in human breast tumor xenografts,” Molecular Imaging and Biology, vol. 8, no. 2, pp 63, 2006. 9. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “SPECT imaging and quantification of Tc-99m-labeled humanized TRA-8 anti-DR5 antibody in human breast and pancreatic tumor xenografts,” Molecular Imaging and Biology, vol. 8, no. 2, pp 72, 2006. 10. Kim H., Chen J., Chaudry H. H., Zinn K. R., “Blood-pool and gated-SPECT imaging confirms enhancement of cardiovascular function by 17 β-estradiol (E2) following severe and prolonged hypotension even without fluid resuscitation in a rat model,” Journal of Nuclear Medicine, vol. 48, suppl. 2, pp 54, 2007. 11. Kim H., Markert J. M., Gillespie G. Y., Samuel S. L., Zinn K. R., “Serial imaging oncolytic herpes simplex virus (HSV) in brain tumor xenografts using luciferase and the human type 2 somatostatin receptor (hSSTr2),” Journal of Nuclear Medicine, vol. 48, suppl. 2, pp 187, 2007. 12. Kim H., Zeng H., Morgan D. E., Ng T. C., Grizzle W. E., Warram J. M., Stockard C. R., Forero-Torres A. Zinn K. R., “Early therapeutic efficacy of an anti-DR5 antibody inducing apoptosis for breast cancer evaluated by diffusion-weighted imaging,” Abstract Book of Joint Molecular Imaging Conference, pp 248, 2007. 13. Kim H., Buchsbaum D. J., Morgan D. E., Zeng H., Ng T. C., Warram J. M., Forero-Torres A. Zinn K. R., “Diffusion-weighted MR imaging (DWI) at 9.4T detects early therapeutic efficacy of an anti-DR5 antibody combined with gemcitabine in an orthotopic pancreatic tumor model,” Abstract Book of Joint Molecular Imaging Conference, pp 41, 2007. 14. Kim H., Morgan D. E., Zeng H., Ng T. C., Grizzle W. E., Warram J. M., Stockard C. R., Forero-Torres A. Zinn K. R., “Evaluation of Early Therapy Response of an Apoptosis-inducing Antibody in Human Breast Tumors Using Diffusion-weighted Imaging at 9.4T,” Scientific Assembly and Annual Meeting Program of Radiological Society of North America, pp 861, 2007. 15. Kim H., Morgan D. E., Buchsbaum D. J., Zeng H., Grizzle W. E., Warram J. M., Stockard C. R., McNally L. R., Long J. W., Sellers J. C., Forero A., Zinn K. R., “Early evaluation of a novel therapy with anti-DR5 antibody and chemotherapy in orthotopic pancreatic tumor xenografts using high field strength diffusion weighted imaging.” Proceedings of American Association for Cancer Research Annual Meeting, vol. 49, pp 881, 2008. 16. Norman E. R., Morgan D. E., Kim H., Pednekar A., Sobol W. T., “Heterogeneity of upper abdominal viscera ADC measurements at 3T: Does position in the bore affect measurement reproducibility?” Scientific Assembly and Annual Meeting Program of Radiological Society of North America, pp 617, 2008. 17. Kim H., Folks K., Guo L., George J. F., Sun Y., Zinn, K. R., “Dynamic Contrast-Enhanced MR Imaging Detected Early Changes in Vascular Permeability following Anti-DR5 Antibody Therapy in Breast Tumor Xenografts” Proceeding of International Society of Magnetic Resonance in Medicine, vol. 17, pp 2300, 2009. 18. Kim H., Folks K., Guo L., George J. F., Sellers J. C., Buchsbaum D. J., Zinn, K. R., “Dynamic Contrast-Enhanced MR imaging for Early Detection of Vascular-Permeability Changes following Combination Therapy with Anti-EGFR Antibody and Irinotecan in Orthotopic Pancreatic Tumor Xenografts: A Pilot Study” Proceeding of International Society of Magnetic Resonance in Medicine, vol. 17, pp 4193, 2009. 19. Morgan D. E., Kim H., Ng T., Christein J., Mohamad E., Pednekar A., “Quantitative Perfusion and Diffusion Weighted Magnetic Resonance Imaging of Pancreatic Adenocarcinoma at 3T: A Pilot Study” American Journal of Roentgenology, vol. 192, A49-A52, 2009. 20. Kim H., Folks K., Guo L., George J. F., Sellers J. C., Buchsbaum D. J., George J. F., Zinn, K. R., “Dynamic Contrast-Enhanced MRI Detects Early Vascular Change in Orthotopic Pancreatic Tumor Xenografts following Anti-EGFR and Irinotecan Therapies” Proceeding of World Molecular Imaging Congress, Abstract nr 0946, 2009. 21. Ivey E., Samuel S., Kim H., Zinn K. R., “Death Receptor 5 (DR5) aggregation by TRA-8 agonist antibody is enhanced by chemotherapy in triple negative (TN) breast cancer cells” Proceeding of World Molecular Imaging Congress, Abstract nr 0315, 2009. 22. Kim H., Folks K., Guo L., Stockard C. R., Fineberg N. S., George J. F., Zinn, K. R., “Novel MRI Biomarkers Measuring Early Response of Breast Tumor Xenografts following Anti-DR5 and Bevacizumab Therapies” Proceeding of World Molecular Imaging Congress, Abstract nr 0212, 2009. 23. Kim H., Folks K., Guo L., Sellers J., Fineberg N., Stockard C., Grizzle W., Buchsbaum D., Morgan D., George J., Zinn K. R., “Early therapy assessment of cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging” Proceedings of the 101st Annual Meeting of the American Association for Cancer Research, Abstract nr 641, 2010. 24. Kim H., Folks K., Guo L., Sellers J., Fineberg N., Stockard C., Grizzle W., Buchsbaum D., Morgan D., George J., Zinn K. R., “Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Early Therapy Evaluation of Combined Anti-EGFR Antibody and Irinotecan in Orthotopic Pancreatic Tumor Xenografts” Proceeding of the 19th Annual Meeting of the International Society of Magnetic Resonance in Medicine, Abstract nr 6384, 2010. 25. Kim H., Zhai G., Liu Z., Helman E, Zhou T, Zinn K. R., Rosenthal E. L., “Therapy evaluation of a novel anti-EMMPRIN monoclonal antibody for orthotopic pancreatic cancer xenografts by ultrasonography” Proceeding of World Molecular Imaging Congress, Abstract nr 0519A, 2010. 26. Kim H., Zhai G., Fineberg N. S., Oliver P. G., Buchsbaum D. J., Zinn K. R., “Early therapy assessment of combined anti-DR5 antibody and abraxane in a triple-negative breast cancer model using diffusion-weighted imaging” Proceeding of World Molecular Imaging Congress, Abstract nr 0530B, 2010. 27. Azure MT, Kim H, Shen S, Yoder DR, Machado RM, Andreoletti G, Maquaire P, Brechbiel MW, Baidoo KW, Milenic DE, Zinn KR, “Radiolabeling and Imaging of 212Pb-TCMC-Herceptin” Proceeding of World Molecular Imaging Congress, Abstract nr 0887B, 2010. 28. Kim H., Zhai G., Fineberg N. S., Oliver P. G., Buchsbaum D. J., Zinn K. R., “Diffusion weighted imaging detects early response of triple-negative breast cancer xenografts following the combination therapy with anti-DR5 antibody and abraxane” Proceeding of ASCO-NCI-EORTC Annual meeting on Molecular Markers in Cancer, Abstract nr 19, 2010. 29. Kim H., Zhai G., Liu Z., Shah N., Helman E., Knowles J. A., Stockard, C. R., Grizzle W. E., Zhou T., Zinn K. R., Rosenthal E., “Novel monoclonal antibody targeting EMMPRIN for pancreatic cancer therapy ” Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research, Abstract nr 4575, 2011. 30. Shah N., Zhai G., Knowles J. A., Stockard, C. R., Grizzle W. E., Fineberg N., Zhou T., Zinn K. R., Rosenthal E., Kim H., “Therapy assessment of a novel anti-EMMPRIN antibody and gemcitabine in an orthotopic pancreatic-tumor murine model by FDG PET/CT imaging ” Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research, Abstract nr 1795, 2011. 31. Shah N., Zhai G., Knowles J. A., Stockard, C. R., Grizzle W. E., Fineberg N., Zhou T., Zinn K. R., Rosenthal E., Kim H., “Serial 18F-FDG PET/CT imaging of pancreatic tumor xenografts to evaluate a novel anti-EMMPRIN mAb and gemcitabine” Journal of Nuclear Medicine, vol. 52, suppl. 2, pp. 1720, 2011. 32. Zhai G., Kim H., Samuel S., Whitworth L., Zinn K. R., “Early therapy assessment of combined anti-DR5 antibody and carboplatin in a triple-negative breast cancer mouse model using diffusion-weighted imaging and 1H MR spectroscopy” Proceeding of World Molecular Imaging Congress, Abstract nr P300, 2011. 33. Kim H., Zhai G., Samuel S., Umphrey H. R., Rana S., Stockard C. R., Fineberg N. S., Guo L., Zinn K. R., “Evaluation of combined EMMPRIN and DR5 targeted therapy using multi-modal imaging in an orthotopic pancreatic cancer model” Proceeding of World Molecular Imaging Congress, Abstract nr P301, 2011. 34. Rana S., Kim H., Zinn K. R., “Tamoxifen increased killing efficiency of DR5 agonist TRA8 in Triple Negative (TN) cancer cell-lines” Proceeding of World Molecular Imaging Congress, Abstract nr P276, 2011. 35. Kim H., Zhai G., Shah N., Samuel S., Umphery H., Stockard C. Fineberg N. Zhou T., Rosenthal E. L. Zinn K. R., “Anti-EMMPRIN therapy for pancreatic cancer” Proceeding of TM’s 1st World Cancer Online Conference, Abstract nr 31, 2012. 36. Ayub A., Kim H., Zhai G., Hubbard W. J., Floyd C. L., Day N. L., Zinn K. R., and Chaudry I. H., “Estrogen sulfate (E2-SO4) administration one hour post-trauma brain injury (TBI) helps to resolve edema, improve metabolism and physiological conditions in the rat brain” Shock, vol. 37, suppl. 1, pp. 44, 2012. 37. Kim H., Zhai G., Samuel S., Rigell C., Umphrey H., Stockard C., Fineberg N., Zinn K. R., “FDG PET/CT imaging evaluates dual combined therapy targeting EMMPRIN and DR5 for pancreatic cancer,” Journal of Nuclear Medicine, vol. 53, suppl. 1, pp 1, 2012. 38. Kim H., Ayub A., Zhai G., Subedi, Hubbard W., Zinn K., Chaudry I., “Evaluation of estrogen-sulphate (E2-SO4) in a rat model of traumatic brain injury,” Journal of Nuclear Medicine, vol. 53, suppl. 1, pp 209, 2012. 39. Kim H., Rigell C., Shah N., Zhai G., Lee K., Samuel S., Martin A., Fineberg N. Beasley M., Zinn K. R., “Differential efficacy of anti-EMMPRIN antibody in combination with gemcitabine according to tumor vascularity in an orthotopic pancreatic tumor model” Proceeding of World Molecular Imaging Congress, Abstract nr P886, 2012. 40. Kim H., Morgan D., Keene K., Sarver D., Lee K., Beasley M., Posey J., “Early evaluation of antiangiogenic therapy for gastrointestinal cancer using dynamic contrast enhanced MRI” c 41. Zhai G., Kim H., Sarver D., Samuel S., Whitworth L, Zinn K. R., “Early therapy assessment of combined TRA-8 and carboplatin in triple-negative breast cancer mouse models using diffusion-weighted imaging and 1H MR spectroscopy” Proceeding of World Molecular Imaging Congress, Abstract nr P118, 2012. 42. Zhai G., Clinton G., Fineberg N., Kim H., “Early therapy assessment of tamoxifen in an MNU-induced mammary cancer rat model using diffusion-weighted imaging” Proceeding of World Molecular Imaging Congress, Abstract nr SS207, 2012. 43. Kim H., “Image-Guided Personalized anti-EMMPRIN Therapy” Proceeding of TM’s 2nd World Cancer Online Conference, Abstract nr 32, 2013. 44. Kim H., Rigell C., Zhai G., Lee K., Samuel S., Martin A., Beasley T., Li L., Boothman D., Zinn K., Dynamic Contrast-Enhanced Magnetic Resonance Imaging enables personalized anti-EMMPRIN therapy for pancreatic cancer” Proceeding of the International Society of Magnetic Resonance in Medicine, 21, Abstract nr 0721, 2013. 45. Zhai G., Grubbs C., Stockard C., Umphrey H., Beasley T., Kim H., “Diffusion-weighted imaging detects early physiologic change of tumor following tamoxifen treatment in an MNU-induced breast-cancer rat model” Proceeding of the International Society of Magnetic Resonance in Medicine, 21, Abstract nr 1751, 2013. 46. Kim H., Rigell C., Zhai G., Lee K., Samuel S., Martin A., Beasley M., Li L., Boothman D., Zinn K. R., “18F-FDG PET/CT imaging validates differential therapeutic effect of anti-EMMPRIN antibody in combination with chemotherapy according to tumor vascularity in pancreatic adenocarcinoma,” Journal of Nuclear Medicine, vol. 54, suppl. 2, pp 648, 2013. 47. Kim H., McKay J., Zelickson A., George M., Samuel S., Zinn K., Gilbert S., “SPECT and micro-CT imaging of an extremity leg-injury rat model,” Journal of Nuclear Medicine, vol. 54, suppl. 2, pp 1204, 2013. 48. Zhai G., Ayub A., Kim H., Samuel S., Chaudry I. H., “Evaluation of ethinyl estradiol (EE-3-SO4) in a rat model of traumatic brain injury using MRI and PET/CT,” Proceeding of World Molecular Imaging Congress, Abstract nr P226, 2013. 49. Kim H., Samuel S., Zhai G., Rana S., Lee K., Martin A., Grubbs C., Zinn K. R., “Dual combination therapy with anti-DR5 antibody and tamoxifen for Triple Negative Breast Cancer (TNBC),” Proceeding of World Molecular Imaging Congress, Abstract nr P250, 2013. 50. Kim H., Rigell C., Zhai G., Lee K., Samuel S., Martin A., Umphrey H., Stockard C., Beasley T., Li L., Boothman D., Zinn K. R., “Vascular-based personalized anti-EMMPRIN therapy for pancreatic cancer,” Proceeding of World Molecular Imaging Congress, Abstract nr P368, 2013. Poster Exhibits 1. Kim H., Furenlid L. R., Crawford M. J., Wilson D. W., Barber B. H., Hunter W. C. J., Barrett H. H., “Small-animal imaging with SemiSPECT,” The Academy of Molecular Imaging Annual Conference, Orlando, FL, March 18-23, 2005. 2. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “High resolution SPECT/CT Imaging of Tc-99m-labeled hTRA-8, a Humanized Anti-DR5 Antibody, in Breast and Pancreatic tumors,” UAB Comprehensive Cancer Center Annual Research Retreat and Research Competition, Birmingham, AL, Oct 24, 2005. 3. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “In vivo imaging of an apoptosis-inducing monomeric antibody (mTRA-8) labeled with Tc-99m in breast tumor xenografts,” UAB Comprehensive Cancer Center Annual Research Retreat and Research Competition, Birmingham, AL, Oct 24, 2005. 4. L. R. Furenlid, H. Kim, and H. H. Barrett, “Data Acquisition and Control Systems for SemiSPECT,” IEEE Nuclear Science Symposium and Medical Imaging Conference, J03-56, Puerto Rico, Oct 23-29, 2005. 5. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “SPECT/CT imaging of breast and pancreatic tumors with Tc-99m-labeled hTRA-8, a humanized anti-DR5 antibody for cancer therapy,” AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference, Philadelphia, PA, Nov 14-18, 2005. 6. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “In vivo imaging of breast cancer xenografts with Tc-99m-labeled mTRA-8, an apoptosis-inducing monomeric antibody targeting DR5,” AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference, Philadelphia, PA, Nov 14-18, 2005. 7. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “In vivo imaging of human breast and pancreatic tumor xenografts with TRA-8, anti-DR5 antibody inducing apoptosis,” 22nd Annual Trainee Research Symposium, Department of Medicine, UAB, Birmingham, AL, March 1, 2006. 8. Wang D., Kim H., Zinn K. R., “A quantification method of SPECT/CT data for analyzing drug distributions in tumors,” The Academy of Molecular Imaging Annual Conference, Orlando, FL, March 25-29, 2006. 9. Kim H., Zeng H., Morgan D. E., Ng T. C., Grizzle W. E., Warram J. M., Stockard C. R., Forero-Torres A. Zinn K. R., “Early therapeutic efficacy of an anti-DR5 antibody inducing apoptosis for breast cancer evaluated by diffusion-weighted imaging,” Joint Molecular Imaging Conference, Providence, Rhode Island, Sept 8-11, 2007. 10. Kim H., Morgan D. E., Buchsbaum D. J., Zeng H., Grizzle W. E., McNally L. R., Warram J. M., Stockard C. R., Long J., Sellers J. C., Zinn K. R., “Diffusion-weighted MRI evaluates early therapeutic efficacy of a novel anti-DR5 antibody in breast and pancreatic tumor xenografts,” UAB Comprehensive Cancer Center Annual Research Retreat and Research Competition, Birmingham, AL, Oct 29, 2007. 11. Kim H., Morgan D. E., Zeng H., Ng T. C., Grizzle W. E., Warram J. M., Stockard C. R., Forero-Torres A. Zinn K. R., “Evaluation of Early Therapy Response of an Apoptosis-inducing Antibody in Human Breast Tumors Using Diffusion-weighted Imaging at 9.4T,” Radiological Society of North America 93rd Scientific Assembly and Annual meeting, Chicago, IL, Nov 25-30, 2007. 12. Kim H., Morgan D. E., Buchsbaum D. J., Zeng H., Grizzle W. E., Warram J. M., Stockard C. R., McNally L. R., Long J. W., Sellers J. C., Forero A., Zinn K. R., “Early evaluation of a novel therapy with anti-DR5 antibody and chemotherapy in orthotopic pancreatic tumor xenografts using high field strength diffusion weighted imaging.” American Association for Cancer Research (AACR) Annual meeting, San Diego, CA, April 12-16, 2008. 13. Kim H., Pednekar A., Sobol W. T., Zinn K. R., “Quantification of distortion effects in diffusion-weighted echo-planar magnetic resonance imaging.” World Molecular Imaging Congress, Nice, France, Sep 10-13, 2008. 14. Kim H., Morgan D. E., Buchsbaum D. J., Long J. W., McNally L. R., Zeng H., Zinn K. R., “The Feasibility of MR Perfusion Imaging in an Orthotopic Pancreatic-Cancer Mouse Model.” World Molecular Imaging Congress, Nice, France, Sep 10-13, 2008. 15. Kim H., Folks K., Guo L., George J. F., Fineberg N., Zinn K. R., “Dynamic Contrast-Enhanced MR Imaging Detects Early Therapeutic Efficacy of a Novel Anti-DR5 Antibody combined with Bevacizumab in Breast Tumor Xenografts.” UAB Comprehensive Cancer Center Annual Research Retreat and Research Competition, Birmingham, AL, Nov 3, 2008. 16. Kim H., Folks K., Guo L., George J. F., Sun Y., Zinn, K. R., “Dynamic Contrast-Enhanced MR Imaging Detected Early Changes in Vascular Permeability following Anti-DR5 Antibody Therapy in Breast Tumor Xenografts” 17th Annual meeting of International Society for Magnetic Resonance in Medicine, Honolulu, HI, April 20-24, 2009. 17. Kim H., Folks K., Guo L., George J. F., Sellers J. C., Buchsbaum D. J., Zinn, K. R., “Dynamic Contrast-Enhanced MR imaging for Early Detection of Vascular-Permeability Changes following Combination Therapy with Anti-EGFR Antibody and Irinotecan in Orthotopic Pancreatic Tumor Xenografts: A Pilot Study” 17th Annual meeting of International Society for Magnetic Resonance in Medicine, Honolulu, HI, April 20-24, 2009. 18. Kim H., Folks K., Guo L., George J. F., Sellers J. C., Buchsbaum D. J., George J. F., Zinn, K. R., “Dynamic Contrast-Enhanced MRI Detects Early Vascular Change in Orthotopic Pancreatic Tumor Xenografts following Anti-EGFR and Irinotecan Therapies” World Molecular Imaging Congress, Montreal, Canada, Sep 23-26, 2009. 19. Ivey E., Samuel S., Kim H., Zinn K. R., “Death Receptor 5 (DR5) aggregation by TRA-8 agonist antibody is enhanced by chemotherapy in triple negative (TN) breast cancer cells” World Molecular Imaging Congress, Montreal, Canada, Sep 23-26, 2009. 20. Kim H., Folks K. D., Guo L., Sellers J. C., Fineberg N., Stockard C. R., Grizzle W. E., Buchsbaum D. J., Morgan D. E., George J. F., Zinn K. R. “Novel MR Biomarkers Measuring Early Response of Orthotopic Pancreatic Adenocarcinoma Xenografts following Cetuximab and Irinotecan Therapies.” UAB Comprehensive Cancer Center Annual Research Retreat and Research Competition, Birmingham, AL, Oct 28, 2009. 21. Beck B. H., Kim H. G, Kim H., Samuel S., Liu Z., Shrestha R., Haines H., Zinn K. R., Lopez R. D. “Adoptively-transferred ex vivo expanded gamma delta-T cells mediate in vivo antitumor activity in preclinical mouse models of breast cancer.” UAB Comprehensive Cancer Center Annual Research Retreat and Research Competition, Birmingham, AL, Oct 28, 2009. 22. Kim H., Folks K., Guo L., Sellers J., Fineberg N., Stockard C., Grizzle W., Buchsbaum D., Morgan D., George J., Zinn K. R., “Early therapy assessment of cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging” American Association for Cancer Research (AACR) Annual meeting, Washington, DC, April 17-21, 2010. 23. Kim H., Zhai G., Liu Z., Helman E, Zhou T, Zinn K. R., Rosenthal E. L., “Therapy evaluation of a novel anti-EMMPRIN monoclonal antibody for orthotopic pancreatic cancer xenografts by ultrasonography” World Molecular Imaging Congress, Kyoto, Japan, Sep 8-11, 2010. 24. Kim H., Zhai G., Fineberg N. S., Oliver P. G., Buchsbaum D. J., Zinn K. R., “Early therapy assessment of combined anti-DR5 antibody and abraxane in a triple-negative breast cancer model using diffusion-weighted imaging” World Molecular Imaging Congress, Kyoto, Japan, Sep 8-11, 2010. 26. Azure MT, Kim H, Shen S, Yoder DR, Machado RM, Andreoletti G, Maquaire P, Brechbiel MW, Baidoo KW, Milenic DE, Zinn KR, “Radiolabeling and Imaging of 212Pb-TCMC-Herceptin” World Molecular Imaging Congress, Kyoto, Japan, Sep 8-11, 2010. 27. Kim H., Zhai G., Fineberg N. S., Oliver P. G., Buchsbaum D. J., Zinn K. R., “Diffusion weighted imaging detects early response of triple-negative breast cancer xenografts following the combination therapy with anti-DR5 antibody and abraxane” ASCO-NCI-EORTC Annual meeting on Molecular Markers in Cancer, Hollywood, FL, Oct 18-20, 2010. 28. Kim H., Zhai G., Liu Z., Shah N., Helman E., Knowles J. A., Stockard, C. R., Grizzle W. E., Zhou T., Zinn K. R., Rosenthal E., “Novel monoclonal antibody targeting EMMPRIN for pancreatic cancer therapy ” American Association for Cancer Research (AACR) Annual meeting, Orlando, FL, April 2-6, 2011. 29. Shah N., Zhai G., Knowles J. A., Stockard, C. R., Grizzle W. E., Fineberg N., Zhou T., Zinn K. R., Rosenthal E., Kim H., “Therapy assessment of a novel anti-EMMPRIN antibody and gemcitabine in an orthotopic pancreatic-tumor murine model by FDG PET/CT imaging ” American Association for Cancer Research (AACR) Annual meeting, Orlando, FL, April 2-6, 2011. 30. Shah N., Zhai G., Knowles J. A., Stockard, C. R., Grizzle W. E., Fineberg N., Zhou T., Zinn K. R., Rosenthal E., Kim H., “Serial 18F-FDG PET/CT imaging of pancreatic tumor xenografts to evaluate a novel anti-EMMPRIN mAb and gemcitabine” Society of Nuclear Medicine (SNM) Annual meeting, San Antonio, TX, June 4-8, 2011. 31. Zhai G., Kim H., Samuel S., Whitworth L., Zinn K. R., “Early therapy assessment of combined anti-DR5 antibody and carboplatin in a triple-negative breast cancer mouse model using diffusion-weighted imaging and 1H MR spectroscopy” World Molecular Imaging Congress, San Diego, CA, Sep 7-10, 2011. 32. Kim H., Zhai G., Samuel S., Umphrey H. R., Rana S., Stockard C. R., Fineberg N. S., Guo L., Zinn K. R., “Evaluation of combined EMMPRIN and DR5 targeted therapy using multi-modal imaging in an orthotopic pancreatic cancer model” World Molecular Imaging Congress, San Diego, CA, Sep 7-10, 2011. 33. Rana S., Kim H., Zinn K. R., “Tamoxifen increased killing efficiency of DR5 agonist TRA8 in Triple Negative (TN) cancer cell-lines” World Molecular Imaging Congress, San Diego, CA, Sep 7-10, 2011. 34. Kim H., Zhai G., Shah N., Samuel S., Umphery H., Stockard C., Fineberg N., Zhou T., Rosenthal E., Zinn K. R., “Evaluation of a novel anti-EMMPRIN antibody for pancreatic cancer treatment using noninvasive multimodal imaging” UAB Comprehensive Cancer Center Annual Research Retreat and Research Competition, Birmingham, AL, Oct 25, 2011. 35. Ayub A., Kim H., Zhai G., Hubbard W. J., Floyd C. L., Day N. L., Zinn K. R., and Chaudry I. H., “Estrogen sulfate (E2-SO4) administration one hour post-trauma brain injury (TBI) helps to resolve edema, improve metabolism and physiological conditions in the rat brain” 7th Congress of the International Federation of Shock Societies 35th Annual Conference on Shock, Miami Beach, FL, June 9-13, 2012. 36. Kim H., Ayub A., Zhai G., Subedi, Hubbard W., Zinn K., Chaudry I., “Evaluation of estrogen-sulphate (E2-SO4) in a rat model of traumatic brain injury,” The 59th annual meeting of Society of Nuclear Medicine, Miami, FL, June 9-13, 2012. 37. Ayub A., Kim H., Zhai G., Hubbard W. J., Floyd C. L., Day N. L., Zinn K. R., and Chaudry I. H., “Salutary Effects of Estrogen Sulfate (E2SO4) following Traumatic Brain Injury (TBI)” Military Health System Research Symposium (MHSRS), Ft Lauderdale, FL, August 13-16, 2012. 38. Kim H., Rigell C., Shah N., Zhai G., Lee K., Samuel S., Martin A., Fineberg N. Beasley M., Zinn K. R., “Differential efficacy of anti-EMMPRIN antibody in combination with gemcitabine according to tumor vascularity in an orthotopic pancreatic tumor model” World Molecular Imaging Congress, Dublin, Ireland, Sep 5-8, 2012. 39. Kim H., Morgan D., Keene K., Sarver D., Lee K., Beasley M., Posey J., “Early evaluation of antiangiogenic therapy for gastrointestinal cancer using dynamic contrast enhanced MRI” World Molecular Imaging Congress, Dublin, Ireland, Sep 5-8, 2012. 40. Zhai G., Kim H., Sarver D., Samuel S., Whitworth L, Zinn K. R., “Early therapy assessment of combined TRA-8 and carboplatin in triple-negative breast cancer mouse models using diffusion-weighted imaging and 1H MR spectroscopy” World Molecular Imaging Congress, Dublin, Ireland, Sep 5-8, 2012. 41. Rigell C., Zhai G., Lee K., Samuel S., Martin A., Beasley T. M., Li L. S., Boothman D., Zinn K. R., Kim H., “Differential therapeutic efficacy of anti-EMMPRIN antibody according to pancreatic-tumor vascularity when combined with chemotherapy” UAB Comprehensive Cancer Center Annual Research Retreat and Research Competition, Birmingham, AL, Oct 29, 2012. 42. Zhai G., Kim H., Sarver D., Samuel S., Whitworth L., Umphrey H., Oelschlager D. K., Beasley T. M., Zinn K. R. “Diffusion Weighted Imaging and 1H MRS detect the early change of triple-negative breast tumors following dual combination therapy with TRA-8 and carboplatin” UAB Comprehensive Cancer Center Annual Research Retreat and Research Competition, Birmingham, AL, Oct 29, 2012. 43. Zhai G., Kim H., Sarver D., Samuel S., Whitworth L., Umphrey H., Oelschlager D. K., Beasley T. M., Zinn K. R. “Early therapy assessment of TRA-8 for triple-negative breast cancer based on diffusion weighted imaging and 1H MRS” 9th Memphis Bioimaging Symposium, Memphis, TN, Nov 1, 2012. 44. Zhai G., Grubbs C., Stockard C. R., Umphrey H. R., Beasley T. M., Kim H., “Diffusion-weighted imaging detects early physiologic change of tumor following tamoxifen treatment in an MNU-induced breast-cancer rat model,” 21st Annual meeting of International Society for Magnetic Resonance in Medicine, Salt Lake City, UT, April 22-26, 2013. 45. Kim H., McKay J., Zelickson A., George M., Samuel S., Zinn K., Gilbert S., “SPECT and micro-CT imaging of an extremity leg-injury rat model,” The 60th annual meeting of Society of Nuclear Medicine, Vancouver, Canada, June 8-13, 2013. 46. Zhai G., Ayub A., Kim H., Samuel S., Chaudry I. H., “Evaluation of ethinyl estradiol (EE-3-SO4) in a rat model of traumatic brain injury using MRI and PET/CT,” World Molecular Imaging Congress, Savannah, GA, Sep 18-21, 2013. 47. Kim H., Samuel S., Zhai G., Rana S., Lee K., Martin A., Grubbs C., Zinn K. R., “Dual combination therapy with anti-DR5 antibody and tamoxifen for Triple Negative Breast Cancer (TNBC),” World Molecular Imaging Congress, Savannah, GA, Sep 18-21, 2013. 48. Kim H., Rigell C., Zhai G., Lee K., Samuel S., Martin A., Umphrey H., Stockard C., Beasley T., Li L., Boothman D., Zinn K. R., “Vascular-based personalized anti-EMMPRIN therapy for pancreatic cancer,” World Molecular Imaging Congress, Savannah, GA, Sep 18-21, 2013. 49. Zhai G., Samuel S., Kim H., Rana S., Lee K., Martin A., Grubbs C., Zinn K. R., “Effect of anti-DR5 antibody and tamoxifen on Triple Negative Breast Cancer (TNBC),” UAB Comprehensive Cancer Center Annual Research Retreat and Research Competition, Birmingham, AL, Nov 5, 2013. 50. Zhai G., Chen B., Kim H., Zinn K., Agarwal A., “Diffusion-weighted imaging detects early progression of renal fibrosis in a murine model of unilateral ureteral obstruction,” 22nd Annual meeting of International Society for Magnetic Resonance in Medicine, Milan, Italy, May 12-16, 2014. 51. Kim H., Morgan D., Sarver D., Lee K., Beasley T., Keene K., “Early assessment of sequential combined therapy with radiation and sorafenib for hepatocellular carcinoma using quantitative perfusion and diffusion weighted magnetic resonance imaging: a pilot study,” 22nd Annual meeting of International Society for Magnetic Resonance in Medicine, Milan, Italy, May 12-16, 2014. 52. Kim H., Arnoletti P., Christein J., Heslin M., Posey J., Pednekar A., Beasley T., Morgan D., “Quantitative perfusion and diffusion weighted magnetic resonance imaging of pancreatic adenocarcinoma: a pilot study,” 22nd Annual meeting of International Society for Magnetic Resonance in Medicine, Milan, Italy, May 12-16, 2014. Oral Presentations Scientific papers presented at national and international meetings 1. Kim H, “Development and Evaluation of SemiSPECT, a Small-Animal Imager Based on Eight CdZnTe Pixel Detectors,” The Academy of Molecular Imaging Annual Conference, Orlando, FL, March 28-31, 2004. 2. Furenlid LR, Chen Y, Wilson DW, Kim H, Barrett HH, “Small animal imaging with FASTSPECT II,” The Academy of Molecular Imaging Annual Conference, Orlando, FL, March 28-31, 2004. 3. Furenlid LR, Kim H, Wilson DW, Chen Y, Liu Z, Stevenson GD, Barber BH, Barrett HH, Woolfenden JM, “Preliminary comparison of small-animal SPECT systems based on scintillators and pixellated cadmium zinc telluride arrays,” The Society of Nuclear Medicine 52nd Annual Meeting, Toronto, Canada, June 18-22, 2005. 4. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “Characterization of Tc-99m-labeled anti-DR5 antibody (mTRA-8) by in vitro analyses and in vivo imaging in human breast tumor xenografts,” The Academy of Molecular Imaging Annual Conference, Orlando, FL, March 25-29, 2006. 5. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “SPECT imaging and quantification of Tc-99m-labeled humanized TRA-8 anti-DR5 antibody in human breast and pancreatic tumor xenografts,” The Academy of Molecular Imaging Annual Conference, Orlando, FL, March 25-29, 2006. 6. Kim H., Chen J., Chaudry H. H., Zinn K. R., “Blood-pool and gated-SPECT imaging confirms enhancement of cardiovascular function by 17 β-estradiol (E2) following severe and prolonged hypotension even without fluid resuscitation in a rat model,” The 54th annual meeting of Society of Nuclear Medicine, Washington, DC, June 2-6, 2007. 7. Kim H., Markert J. M., Gillespie G. Y., Samuel S. L., Zinn K. R., “Serial imaging oncolytic herpes simplex virus (HSV) in brain tumor xenografts using luciferase and the human type 2 somatostatin receptor (hSSTr2),” The 54th annual meeting of Society of Nuclear Medicine, Washington, DC, June 2-6, 2007. 8. Kim H., Buchsbaum D. J., Morgan D. E., Zeng H., Ng T. C., Warram J. M., Forero-Torres A. Zinn K. R., “Diffusion-weighted MR imaging (DWI) at 9.4T detects early therapeutic efficacy of an anti-DR5 antibody combined with gemcitabine in an orthotopic pancreatic tumor model,” Joint Molecular Imaging Conference, Providence, Rhode Island, Sept 8-11, 2007. 9. Norman E. R., Morgan D. E., Kim H., Pednekar A., Sobol W. T., “Heterogeneity of upper abdominal viscera ADC measurements at 3T: Does position in the bore affect measurement reproducibility?” Radiological Society of North America 94th Scientific Assembly and Annual meeting, Chicago, IL, Nov 30-Dec 5, 2008. 10. Morgan D. E., Kim H., Ng T., Christein J., Mohamad E., Pednekar A., “Quantitative Perfusion and Diffusion Weighted Magnetic Resonance Imaging of Pancreatic Adenocarcinoma at 3T: A Pilot Study” Society of Computed Body Tomography and Magnetic Resonance 32nd Annual Course, Miami Beach, FL, March 1-6, 2009. 11. Morgan D. E., Kim H., Ng T., Christein J., Mohamad E., Pednekar A., “Quantitative Perfusion and Diffusion Weighted Magnetic Resonance Imaging of Pancreatic Adenocarcinoma at 3T: A Pilot Study” American Roentgen Ray Society Annual Meeting, Boston, MA, April 26-May 1, 2009. 12. Kim H., Folks K., Guo L., Stockard C. R., Fineberg N. S., George J. F., Zinn, K. R., “Novel MRI Biomarkers Measuring Early Response of Breast Tumor Xenografts following Anti-DR5 and Bevacizumab Therapies” World Molecular Imaging Congress, Montreal, Canada, Sep 23-26, 2009. 13. Kim H., Folks K., Guo L., Sellers J., Fineberg N., Stockard C., Grizzle W., Buchsbaum D., Morgan D., George J., Zinn K. R., “Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Early Therapy Evaluation of Combined Anti-EGFR Antibody and Irinotecan in Orthotopic Pancreatic Tumor Xenografts” 18th Annual meeting of International Society for Magnetic Resonance in Medicine, Stockholm, Sweden, May 3-7, 2010. 14. Kim H., Zhai G., Shah N., Samuel S., Umphery H., Stockard C. Fineberg N. Zhou T., Rosenthal E. L. Zinn K. R., “Anti-EMMPRIN therapy for pancreatic cancer” TM’s 1st World Cancer Online Conference, January 12-14, 2012. 15. Kim H., Zhai G., Samuel S., Rigell C., Umphrey H., Stockard C., Fineberg N., Zinn K. R., “FDG PET/CT imaging evaluates dual combined therapy targeting EMMPRIN and DR5 for pancreatic cancer,” The 59th annual meeting of Society of Nuclear Medicine, Miami, FL, June 9-13, 2012. 16. Zhai G., Clinton G., Fineberg N., Kim H., “Early therapy assessment of tamoxifen in an MNU-induced mammary cancer rat model using diffusion-weighted imaging” World Molecular Imaging Congress, Dublin, Ireland, Sep 5-8, 2012. 17. Kim H., “Image-guided personalized anti-EMMPRIN therapy” TM’s 2nd World Cancer Online Conference, January 8-11, 2013. 18. Kim H., Rigell C., Zhai G., Lee K., Samuel S., Martin A., Beasley T., Li L., Boothman D., Zinn K. R., “Dynamic Contrast-Enhanced Magnetic Resonance Imaging enables personalized anti-EMMPRIN therapy for pancreatic cancer,” 21st Annual meeting of International Society for Magnetic Resonance in Medicine, Salt Lake City, UT, April 22-26, 2013. 19. Kim H., Rigell C., Zhai G., Lee K., Samuel S., Martin A., Beasley M., Li L., Boothman D., Zinn K. R., “18F-FDG PET/CT imaging validates differential therapeutic effect of anti-EMMPRIN antibody in combination with chemotherapy according to tumor vascularity in pancreatic adenocarcinoma,” The 60th annual meeting of Society of Nuclear Medicine, Vancouver, Canada, June 8-13, 2013. 20. Kim H., “Imaging for precision cancer medicine” TM’s 3rd World Cancer Online Conference, January 21-24, 2014. 21. Kim H., Morgan D., Sarver D., Lee K., Beasley T., Posey J., “Early therapy evaluation of sunitinib for gastrointestinal stromal tumors using quantitative perfusion and diffusion weighted magnetic resonance imaging: a pilot study,” 22nd Annual meeting of International Society for Magnetic Resonance in Medicine, Milan, Italy, May 12-16, 2014. Scientific papers presented at local and regional meetings 1. Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “In vivo imaging of TRA-8, an apoptosis-inducing antibody targeting DR5 in human breast and pancreatic tumor xenografts,” Postdoctoral Research Competition, UAB Postdoctoral Association, Birmingham, AL, March 7, 2006. 2. Kim H., Folks K. D., Guo L., Sellers J. C., Buchsbaum D. J., George J. F., Morgan D. E., Zeng H., Grizzle W. E., Warram J. M., Stockard C. R., McNally L. R., Long J. W., Forero A., Zinn K. R., “Physiologic MRI for Early Therapy Assessment in Pancreatic Adenocarcinoma”, UAB Center for Clinical and Translational Science (CCTS), Birmingham, AL, August 26, 2009. 3. Kim H., Folks K. D., Guo L., Sellers J. C., Buchsbaum D. J., George J. F., Morgan D. E., Zeng H., Grizzle W. E., Warram J. M., Stockard C. R., McNally L. R., Long J. W., Forero A., Zinn K. R., “Physiologic MRI for Early Therapy Assessment in Pancreatic Adenocarcinoma”, 1st Annual CCTS (Center for Clinical and Translational Science) Scientific Symposium, Birmingham, AL, Oct 1, 2009. Invited workshops, etc. at national postgraduate courses, meetings and at other universities 1. “Development of High-Resolution Small-Animal SPECT Imager and in vivo Small-Animal SPECT/CT Imaging for Drug Development,” Department of Radiology in Washington University, St. Louis, MO, March 9, 2006. 2. “Muti-modal imaging to evaluate a novel anti-DR5 antibody, TRA-8, in breast and pancreatic tumor xenografts,” The 20th Annual Symposium of the US Central Chapter of the International Isotope Society, Hebron, KY, Sept 27-28, 2007. 3. “Physiologic MRI for Early Therapy Assessment in Pancreatic Adenocarcinoma”, 2nd Annual Scientific Session of Pancreatic Cancer Action Network, Los Angeles, CA, Oct 16-18, 2009. 4. “Early evaluation of anti-DR5 therapy for breast and pancreatic cancers using non-invasive imaging”, Department of Radiology at Seoul National University, Seoul, Korea, Sep 16, 2010. 5. “Evaluation of targeted cancer therapy using non-invasive imaging”, Department of Biology at Georgia State University, Atlanta, GA, Oct 29, 2010. 6. “Personalized anti-EMMPRIN Therapy for Pancreatic Cancer”, 9th Memphis Bioimaging Symposium, Memphis, TN, Nov 1-2, 2012. 7. “Personalized image-guided anti-DR5 therapy for cancer”, Advanced Image Analysis Symposium, Birmingham, AL, April 1, 2013. Invited lectures at local and regional courses and meetings 1. “Evaluation of a novel agonistic anti-DR5 antibody based on multi-modal imaging,” Radiology Grand Round, University of Alabama at Birmingham, Birmingham, AL, December 4, 2007. 2. “Introduction to Image Analysis in Medicine,” Radiology Noon Conference, University of Alabama at Birmingham, Birmingham, AL, February 6, 2008. 3. “Introduction to Tissue Imaging,” Tissue Engineering (BME 435/535), University of Alabama at Birmingham, Birmingham, AL, March 11, 2008. 4. “State-of-the-Art SPECT,” Radiology Noon Conference, University of Alabama at Birmingham, Birmingham, AL, April 18, 2008. 5. “Introduction to Tissue Imaging,” Tissue Engineering (BME 435/535), University of Alabama at Birmingham, Birmingham, AL, April 9, 2009. 6. “Principle of Nuclear Medicine Imaging,” Nuclear Medicine Technology Program, University of Alabama at Birmingham, Birmingham, AL, June 22, 2009. 7. “Introduction to Tissue Imaging,” Tissue Engineering (BME 435/535), University of Alabama at Birmingham, Birmingham, AL, April 15, 2010. 8. “Small animal imaging with microPET/CT and microSPECT/CT: application for cardiac disease,” Noon Conference, Department of Medicine, Division of Cardiology, University of Alabama at Birmingham, Birmingham, AL, April 27, 2010. 9. “Preclinical imaging for targeted cancer-therapy evaluation,” BME Seminar, Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, Oct 22, 2010. 10. “Introduction to Tissue Imaging,” Tissue Engineering (BME 435/535), University of Alabama at Birmingham, Birmingham, AL, April 12, 2011. 11. “Introduction to Tissue Imaging,” Tissue Engineering (BME 435/535), University of Alabama at Birmingham, Birmingham, AL, April 17, 2012. 12. “Diffusion and perfusion MRI for abdominal cancer,” Gastrointestinal working group meeting, University of Alabama at Birmingham, Birmingham, AL, April 20, 2012. 13. “Diffusion weighted imaging for head and neck cancer,” Head and Neck Cancer Think Tank meeting, University of Alabama at Birmingham, Birmingham, AL, November 21, 2012. 14. “Anti-EMMPRIN therapy for pancreatic cancer,” Radiology Noon Conference, University of Alabama at Birmingham, Birmingham, AL, December 5, 2012. 15. “Image-guided personalized therapy for pancreatic cancer”, Radiology Grand Round, University of Alabama at Birmingham, Birmingham, AL, February 11, 2013. 16. “Introduction to Tissue Imaging,” Tissue Engineering (BME 435/535), University of Alabama at Birmingham, Birmingham, AL, April 18, 2013. 17. “Image-guided personalized therapy for cancer”, UAB Imaging Retreat, Birmingham, AL, May 13, 2013. 18. “Preclinical and clinical MR imaging and analysis”, Radiology Research Quarterly – Advanced Imaging Analysis Expo, Birmingham, AL, May 15, 2013. 19. “Vascular-guided personalized therapy for pancreatic cancer”, UAB Center for Clinical and Translational Science (CCTS) Nascent Panel meeting, Birmingham, AL, May 22, 2013. 20. “Physiological MRI for Abdominal Cancers”, Joint meeting of Drs. Zinn and Rosenthal’s labs, Birmingham, AL, September 9, 2013. 21. “Imaging for precision medicine,” Radiology Noon Conference, University of Alabama at Birmingham, Birmingham, AL, October 17, 2013. 22. “Medical Image Analysis,” Radiology Noon Conference, University of Alabama at Birmingham, Birmingham, AL, January 17, 2014. 23. “Nuclear medicine and molecular imaging,” Vivo Imaging Interactive Lecture / Lab (GBS787), University of Alabama at Birmingham, Birmingham, AL, March 7, 2014. 24. “Introduction to Tissue Imaging,” Tissue Engineering (BME 435/535), University of Alabama at Birmingham, Birmingham, AL, April 15, 2014.

Society Memberships
Organization Name Position Held Org Link
American Association for Cancer Research  Full member   
International Society for Magnetic Resonance in Medicine  Full member   
Radiological Society of North America  Associate member   
Society of Nuclear Medicine  Full member   
World Molecular Imaging Congress  Full member   
 



Research/Clinical Interest
Title
Cancer imaging
Description
To establish novel MRI/MRS and PET/CT protocols for early assessment of cancer therapies, enabling precision medicine. To evaluate novel drugs for cancer and cardiac disease using MRI/PET/SPECT imaging.

Selected Publications 
Publication PUBMEDID
Furenlid L. R., Wilson D. W., Chen Y., Kim H., Pietraski P. J., Crawford M. J., and Barrett H. H., “FASTSPECT II: A Second-Generation High-Resolution Dynamic SPECT Imager,” IEEE Transactions on Nuclear Science, vol. 51, pp. 631-635, 2004.   20877439  
Kim H., Chen J., Zinn K. R., Hubbard W. J., Fineberg N. S., Chaudry I. H. “Single Photon Emission Computed Tomography Demonstrated Efficacy of 17β-estradiol Therapy in Male Rats following Trauma-Hemorrhage and Extended Hypotension.” J Trauma, vol. 69, pp. 1266-1273, 2010. Epub: 21 June 2010.  20571453 
Kim H., Folks K. D., Guo L., Stockard C. R., Grizzle W. E., Fineberg N., George J. F., Zinn K. R. “Dynamic Contrast Enhanced Magnetic Resonance Imaging to Detect Early Vascular Response in Breast Tumor Xenografts following Anti-DR5 Therapy.” Molecular Imaging and Biology, vol. 13, pp. 94-103, 2011  20383593 
Beck B. H., Kim H. G., Kim H., Samuel S., Liu Z., Shrestha R., Haines H., Zinn K., Lopez R. D., “Adoptively transferred ex vivo expanded gammadelta-T cells mediate in vivo antitumor activity in preclinical mouse models of breast cancer,” Breast Cancer Res Treat, vol. 122, pp. 135-44, 2010.   19763820 
Kim H., Morgan D. E., Buchsbaum D. J., Zeng H., Grizzle W. E., Warram J. M., Stockard C. R., McNally L. R., Long J. W., Forero-Torres A., Zinn K. R., “Early Therapy Evaluation of Combined Anti-DR5 Antibody and Gemcitabine in Orthotopic Pancreatic Tumor Xenografts by Diffusion-Weighted Magnetic Resonance Imaging,” Cancer Research, vol. 68, pp. 8369-8376, 2008.  18922909 
Kim H., Morgan D. E., Zeng H., Grizzle W. E., Warram J. M., Stockard C. R., Wang D., Zinn K. R., “Breast Tumor Xenografts: Diffusion-Weighted MR Imaging to Assess Early Therapy with Novel Apoptosis-Inducing Anti-DR5 Antibody,” Radiology, vol. 248, pp. 844-851, 2008.  18710978 
Oliver P. G., LoBuglio A. F., Zinn K. R., Kim H., Nan L., Zhou T., Wang W., Buchsbaum D. J., “Treatment of human colon cancer xenografts with TRA-8 anti-death receptor 5 antibody alone or in combination with CPT-11.” Clinical Cancer Research, vol. 14, pp. 2180-2189, 2008.  18381960 
Cowey S., Szafran A. A., Kappes J., Zinn K. R. Siegal G. P. Desmond R. A., Kim H., Evans L., Hardy R. W., “Breast cancer metastasis to bone: Evaluation of bioluminescent imaging and microSPECT/CT for detecting bone metastasis in immunodeficient mice,” Clinical and Experimental Metastasis, vol. 24, pp. 389-401, 2007.  17541709 
Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “High resolution single-photon emission computed tomography and x-ray computed tomography Imaging of Tc-99m-labeled anti-DR5 antibody in breast tumor xenografts,” Molecular Cancer Therapeutics, vol. 6, pp. 866-875, 2007.  17363481 
Kim H., Furenlid L. R. Crawford M. J., Wilson D. W., Barber H. B., Peterson T. E., Hunter W. C. J., Liu Z. Woolfenden J. M. and Barrett H. H., “SemiSPECT: A small-animal single-photon emission computed tomography (SPECT) imager based on eight cadminum zinc telluride (CZT) detector arrays,” Medical Physics, vol. 33, No. 2, pp. 465-475, 2006   16532954 
Kim H., Chaudhuri T. R., Buchsbaum D. J., Wang D., Zinn K. R., “Single-photon emission computed tomography imaging with a humanized, apoptosis-inducing antibody targeting human death receptor 5 in pancreas and breast tumor xenografts.” Cancer biology and therapy, vol. 6, pp. 1396-1402, 2007    
 

Keywords
DWI, DCE-MRI, PET, SPECT, breast cancer, pancreatic cancer