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Faculty Listing
Last Name First Name Research/Clinical Interest Title Keywords
ACOSTA EDWARD Bioanalysis and pharmacometrics of antiviral agents pharmacokinetics, antivirals, antiretrovirals
AGARWAL ANUPAM Regulation of heme oxygenase gene expression in kidney and vascular injury heme oxygenase, acute kidney injury, transplant nephrology, lymphangiogenesis
AMBALAVANAN NAMASIVAYAM Neonatal lung development and Bronchopulmonary Dysplasia Lung, Hypoxia, Hyperoxia, Retinoids, Prediction models
ANANTHARAMAIAH GATTADAHALLI Apolipoproteins, Amphipathic Helices and Atherosclerosis
ATKINSON THOMAS Primary Immunodeficiency and the Role of Infection in Chronic Diseases asthma, mycoplasma, arthritis, primary immunodeficiency
BAILEY SHANNON Molecular mechanisms of chronic alcohol and obesity induced fatty liver disease Molecular mechanisms of alcohol and obesity induced liver diseases; Mitochondrial dysfunction in disease; Molecular bioenergetics; Circadian biology; Redox Signaling; Toxicology
BALKOVETZ DANIEL Epithelial Cell Biology; Epithelial Cell Signal Regulation; Regulation of paracellular transport across epithelial cell tight junctions epithelial cells, claudins, tight junctions, E-cadherin, hepatocyte growth factor, ERK, MDCK
BALLINGER SCOTT Environmental cardiology, free radical biology, mitochondrial function, mitochondrial - nuclear interactions mitochondria, oxidative stress, evolutionary medicine, cardiovascular disease, cancer, metabolism
BAMMAN MARCAS Exercise as a discovery tool and treatment in regenerative medicine and medical rehabilitation. exercise medicine, medical rehabilitation, regenerative medicine, clinical trial, muscle biology
BARNES HELEN Proteomics of neuroprotective and chemopreventive actions of dietary phytochemicals neuroprotection, proteomics, protein modifications, antioxidant dietary supplements, menopause, neurogenesis
BARNES STEPHEN Bile acids, polyphenols and metabolism, and their effects on protein expression and function in chronic disease bile acids, isoflavonoids and polyphenols, metabolomics, proteomics, mass spectrometry
BELLIS SUSAN Role of glycosylation in tumor progression and metastasis tumorigenesis, metastasis, cancer stem cell, cell invasion, apoptosis, tumor immunology,
BENVENISTE ETTY Immune/nervous system interactions
BEVENSEE MARK Cellular and Molecular Physiology of Acid-base Transporters and pH Regulation acid-base, bicarbonate, transporter, brain, fluorescence dyes, glia , heart, intracellular pH, microelectrodes, neuron, Xenopus oocyte, neuronal firing, kidney, polycystic kidney disease, epithelial sodium channel
BHATNAGAR SUSHANT Identification and characterization of novel factors in insulin secretion in obesity and type 2 diabetes Obesity, Type 2 Diabetes, Beta Cell Biology, Insulin Secretion, SNARE Biology, Secreted Proteins, Insulin Granule Trafficking, Tomosyn Proteins, Post-translational Modifications
BJORNSTI MARY-ANN DNA topoisomerase I, yeast genetics, cancer chemotherapeutics, TOR signaling, SUMOylation, DNA damage response, drug resistance, siRNA screening, breast cancer
BLALOCK JAMES Rational Drug and Vaccine Design/Neutrophilic Inflammation
BRENNER MICHAEL Molecular Sudies of Astrocytes in Health and Disease astrocyte, GFAP, transcription, neurodegeneration, transgenic mice
BRIDGES STANLEY Genetic influences on susceptibility, severity, and treatment response in rheumatoid arthritis Rheumatoid arthritis; genetics; African-Americans; pharmacogenetics; biomarkers; autoantibodies
BRILES DAVID Pneumococcal virulence factors; mechanisms of action and use in vaccine Streptococcus pneumoniae, virulence, host immunity, vaccines, virulence factors, mechanisms of virulence, vaccine antigens
BRITT WILLIAM Human Herpesviruses, Molecular Virology and Pathogenesis cytomegalovirus, perinatal infections, virus assembly
BROWN ELIZABETH Molecular and Genetic Epidemiology of Immune-Mediated Clinical Phenotypes multiple myeloma, autoimmune, lupus, genetics, genomics, epidemiology
BUCHSBAUM DONALD Cancer immunotherapy Immunotherapy, Wnt inhibitors, pancreatic cancer, breast cancer, ovarian cancer
BURROWS PETER B Lymphocyte Development and Function B lymphocyte, development, molecular biology
CHANG CHENBEI Growth Factor Signaling and Transcription Regulation in Vertebrate Development TGF-beta, neural induction, BMP, ErbB, gastrulation, cell movement
CHATHAM JOHN Cardiomyocyte function and survival in ischemia/reperfusion and the impact of diabetes: Myocardial ischemia, diabetic cardiomyopathy, O-GlcNAc, STIM1, Ca2+-signaling
CHATTOPADHYAY DEBASISH Structure-Function Analysis of Proteins Structural biology, Protein structure function, Malaria, Chagas' disease, Parasitic disease, Small pox, Bacterial pneumoniae
CHAUDRY IRSHAD Cardiovascular/Immunological Alterations Following Trauma-Sepsis trauma, hemorrhage, sepsis, gender dimorphism, immune functions, cardiovascular functions
CHEN SHU Basic and translational research on neurodegenerative diseases (Alzheimer's, Parkinson's, Dementia, ALS) Alzheimer's disease, Parkinson's disease, dementia, ALS, alpha-synuclein, Tau, biomarkers
CHESNOKOV IGOR DNA Replication and Cell Cycle in Eukaryotes DNA replication, cytokinesis, Origin Recognition Complex
CHILDERS NOEL Development Of A Vaccine For The Prevention Of Dental Caries
CHOW LOUISE Human papillomavirus DNA replication and pathogenesis HPV infections and cancers
COWELL RITA Cellular Vulnerability in Development and Aging: Using the Molecular Phenotype of Neurons to Elucidate Mechanisms of Disease and Identify Targets for Intervention Transcription, Parkinson Disease, ALS, frontotemporal dementia, movement disorders, Neuroanatomy, Metabolism, Mitochondria, Neurobiology, Mouse models
DARLEY-USMAR VICTOR Mitochondrial Health; Bench to Bedside mitochondria, nitric oxide, reactive oxygen species, bioenergetic dysfunciton, translational research
DAVIS RANDALL The developmental immunology of lymphocytes and immunoreceptor biology. Lymphoproliferative disorders and mechanisms that contribute to lymphomagenesis and autoimmunity. Immunology, lymphoproliferative disorders, autoimmunity, B cells, Fc receptors, CLL, FCRL
DELL'ITALIA LOUIS Mechanisms of Remodeling of the Heart in Heart Failure
DOBRUNZ LYNN Hippocampal Synaptic Transmission and Plasticity, Circuits that Regulate Anxiety, Noninvasive Neuromodulation anxiety, Neuropeptide Y, hippocampus
DYBVIG KEVIN Pathogenic mechanisms of mycoplasmas
EBERHARDT ALAN
EDBERG JEFFREY Genetic Polymorphisms in Wegener’s Granulomatosis
ELSON CHARLES Regulation of mucosal immune responses T reg cells, dendritic cells, colitis, mucosal, Crohn's disease, transgenic, IgA, Th IL17
FAST VLADIMIR Mechanisms of cardiac arrhythmias and defibrillation
FENG XU The RANKL/RANK/OPG System in Health and Disease RANKL, RANK, OPG, Cell Differentiation, Cell Signaling, Osteoclast, Mammary Gland, Breast Cancer
FRANK STUART Growth Hormone Action and GH Receptor Structure and Function growth hormone, signaling, prolactin, IGF-1, growth factors
FULLER CATHERINE ENaC/ASIC Ion Channels; Sodium channels, glioma, migration, proliferation, cancer, signaling, polycystic kidney disease
GAMLIN PAUL Studies of the Neural Bases of Vision & Eye Movements pupil, vergence, gene therapy, fMRI
GARVEY W. Molecular and physiological pathogenesis of human insulin resistance Insulin resistance, obesity, Metabolic Syndrome, Type 2 Diabetes
GAWNE TIMOTHY Information Processing in the Central Nervous System EEG, MEG, myopia, schizophrenia, cerebral cortex, vision, retina
GOEPFERT PAUL Determining the mechanisms allowing T cells to control HIV replication in vivo
GOWER BARBARA Dietary and physiologic determinants of chronic disease
GROSS ALECIA GPCR trafficking in neurons and rhodopsin-mediated retinal degenerations rhodopsin, autosomal dominant retinitis pigmentosa, GPCR trafficking, rab11, nudC, MKS proteins, NPHP proteins, BBS proteins, retinal degeneration, inflammatory response in retina, cilia, protein trafficking
HABLITZ JOHN Cellular Mechanisms of Neurotransmission
HARTMAN JOHN Experimental models of gene interaction networks that buffer human disease using cell array phenotyping of yeast gene knockout libraries yeast genetics, quantitative high throughput cell array phenotyping (Q-HTCP), gene interaction networks, cellular quiescence, aging, cystic fibrosis, chemotherapy response, systems biology, drug discovery, lab automation
HEL ZDENEK Immunology and pathogenesis of HIV-1 / AIDS; Neutrophil biology; Effect of hormonal contraception on immune system; Design of novel strategies for immunotherapy of cancer; Covid-19. Immunology, Neutrophils, HIV-1, Vaccine, Cancer, Covid-19.
HERSKOWITZ JEREMY Neurobiology of Alzheimer's Disease Neurodegeneration, Alzheimer's disease, amyloid, signaling, plasticity, behavior, neuroscience, cell biology
HILDRETH BLAKE Role of macrophages and osteoclasts in bone metastasis and primary bone tumors macrophage, osteoclast, breast cancer, primary bone tumor, bone, metastasis
HJELMELAND ANITA Targeting Brain Tumor Initiating Cells and the Tumor Microenvironment Brain Tumor, Tumor Microenvironment, Tumor Initiating Cell, Cancer Stem Cell
HOWARD GEORGE
HU HUI Transcriptional regulation of adaptive immunity in viral infections, allergy, and tumor models Tfh cell differentiation, germinal center and humoral responses, CD8+ T cell activation and exhaustion, immune memory, vaccines
JAVED AMJAD Genetic and Molecular Signaling for Cellular Differentiation and Skeletogenesis Osteoblast, Bone Development, Gene Regulation, Osteoporosis
JUN HO-WOOK Nanostructured Biomaterials, Stem Cells, Tissue Engineering, tissue engineering, nanotechnology, biomaterials, stem cells,
JUSTEMENT LOUIS Elucidation of molecular mechanisms that control B cell class switching and terminal differentiation Lymphocyte Biology, Signal Transduction, B cell differentiation, Adaptor Proteins, Innate immunity, Neutrophil biology,
KANO SHINICHI Immunology of brain homeostasis and disease Neuroimmunology, Glia, Cytokine, Epigenetics, Extracellular vesicles, Schizophrenia
KAPP JUDITH Immune regulation and transplantation immunity; immune tolerance; immune regulation; transplantation; autoimmunity
KATZ JANNET Vaccine delivery systems; inflammation; innate immunity Periodontal disease, gingivalis, immune responses, mucosal vaccines
KIMBERLY ROBERT Autoimmunity, Molecular Mechanisms and Genetic Risk autoimmunity, immune-mediated inflammatory disease, Fc receptors, single nucleotide polymorphisms, immunogenetics, functional genomics
KING PETER 1) RNA Regulation of Inflammation in ALS and other Neurodegenerative Disorders, 2) Smads as Biomarkers of ALS Disease Progressionh RNA stability; AU-rich elements; cytokines and chemokines; glioblastoma; amyotrophic lateral sclerosis, stroke, spinal cord injury, HuR, KSRP
KLUG CHRISTOPHER Hematopoietic stem cell biology, acute leukemia, and pancreatic cancer
KRAFT TIMOTHY Physiology and Pathophysiology of Photoreceptors
KRISHNA NEPALLI Structural Biology and Biomolecular NMR Spectroscopy Proteins, Structural Biology, NMR
LEAVENWORTH JIANMEI Cancer-Immune cell Crosstalk: Discovery of new targets for cancer immunotherapy Immunology, Cancer Immunology, Immunotherapy, Treg, NK cells, glioma
LEFKOWITZ ELLIOT Microbial Genomics and Evolution; Bioinformatics, and Clinical Informatics Viruses, Evolution, Genomics, Bioinformatics, Biomedical Informatics
LIU RUI-MING Oxidative stress, Aging, Lung fibrosis, Alzheimer's disease
LU RUI Epigenetic Mechanisms in Cancer Initiation, Maintenance, and Drug Resistance Cancer, Leukemia, Epigenetics, Genomics, Chromatin, Gene regulation, Novel therapeutics
MANNE UPENDER Translational research in grastrointestinal malignancies and breast cancer Colorectal Cancer, GI malignancies, Breast Cancer, Molecular Biomarkers, Ancestry Differences, Population-based Studies, ancer Control & Prevention
MARKERT JAMES Engineering Herpes Simplex Viruses for the Therapy of Cancer glioma, gene therapy, brain tumors, herpes simplex, cancer therapy, immunotherapy, anti-angiogenic therapy
MATALON SADIS Free Radical Protection from and Exacerbation of Lung Injury Acute Lung Injury, pulmonary edema, pulmonary surfactant, alveolar epithelium, free radicals, nitric oxide, sodium channels
MESTECKY JIRI Mucosal Immunity; Vaccines
MICHALEK SUZANNE Immunological mechanisms involved in host/microbial interactions, and development of mucosal vaccines against infectious agents mucosal vaccines, inflammation, TLRs, T cell, cytokines, signaling pathways
MORROW CASEY Role of the Microbiome in Health and Disease Microbiome Management, Dysbiosis, NextGen DNA sequencing, Bioinformatics, Fecal Transplants, Cancer Metabolism, Drug/Antibiotic Impact On the Microbiome
MOUNTZ JOHN autoimmunity, immune senescence, gene therapy type I IFNs, IL-23, germinal centers, marginal zone macrophages, inflammatory macrophages, rheumatoid arthritis, lupus
MURPHY-ULLRICH JOANNE Extracellular Matrix Control of Cell and Growth Factor Function, multiple myeloma, diabetic complications, glaucoma atherosclerosis, diabetic complications, tumor microenvironment, multiple myeloma, osteolytic bone disease, glaucoma, fibrosis, TGF-beta, thrombospondin
NABORS LOUIS
NAHM MOON Adaptive and Innate Immune Responses to Pneumococci and Pneumonia Vaccines pneumococcus, capsule, innate immunity, pathogenesis, vaccines
NAMAKKAL SOORAPPAN RAJASEKARAN Nrf2/Keap1 dependent mechanisms for reductive stress in heart and brain Reductive Stress, Nrf2-Keap1 Signaling, Cardiac Remodeling, Proteotoxicity, Cardiac Aging, Neurodegeneration, Alzheimer's disease
NIEDERWEIS MICHAEL Novel proteins in the outer membrane of mycobacteria: Functions, structures, role in tuberculosis and applications tuberculosis, virulence, antibiotic resistance, membrane, proteins, transport, nanotechnology
PATEL RAKESH Modulation of Inflammation by Reactive Species and N-glycans vascular, hemoglobin, red cells, Inflammation, isoflavones, Nitric oxide, nitrite, N-glycan, matrikine
PERCY ALAN Rare Disease CRC for New Therapies and New Diagnostics Rett syndrome, MECP2, phenotype, genotype, natural history, longevity
PITTLER STEVEN Basic and Translational Studies of Photoreceptor Metabolism and Retinal Degeneration retinitis pigmentosa, phosphodiesterase, cGMP-gated cation channel, photoreceptor, phototransduction
PLACZEK WILLIAM Anti-cancer target validation and structure-based drug discovery. NMR spectroscopy, cancer, drug discovery, peptide synthesis, structural biology, apoptosis, signaling
POGWIZD STEVEN
PONNAZHAGAN SELVARANGAN Experimental Cancer Therapeutics and BOne Diseases: From Basic to Preclinical Studies Breast Cancer; Prostate Cancer; Osteoimmunology; Bone Metastasis; Osteogenesis; Bone Fracture; Stem Cell Therapy
POZZO-MILLER LUCAS Neurotrophins in Synapse Development and Plasticity, Intellectual Disabilities, and Syndromic Autisms BDNF, Ca2+, Synapse, Rett Syndrome, Hippocampus, Dendritic Spines, MeCP2, Autism, Intellectual Disability
PREVELIGE PETER Structural Biology of Viral Assembly and Infection
RAMAN CHANDER Lymphocyte activation, immunopathogenesis of systemic and neuroimmune autoimmune disease, inflammatory diseases of the skin. Autoimmunity, Multiple Sclerosis, Skin inflammatory diseases
REN BIN Epigenetic and Transcriptional Regulation of Functional Angiogenesis and Arteriogenesis in Cancer, Heart and Vascular Diseases, Alzheimer's Disease and Diabetes. Endothelial cells, Angiogenesis, Arteriogenesis, Molecular and cellular biology, Cancer, Ischemic heart and vascular diseases, Diabetes, Alzherimer's disease
ROBERSON ERIK Neurobiology of Alzheimer's Disease and Frontotemporal Dementia Neurodegeneration, Alzheimer's disease, frontotemporal dementia, tau, progranulin, excitability, signaling, plasticity, behavior
ROGERS JACK
RYAN THOMAS Stem Cell Therapies in Animal Models of Human Disease Sickle cell anemia, thalassemia, embryonic stem cells, hemoglobin, mutagenesis, gene regulation
SANDERS PAUL Mechanisms of Disease Progression in the Kidney salt-sensitive hypertension, transforming growth factor-ß, nitric oxide, hypertensive nephrosclerosis, monoclonal immunoglobulin light-chain-related renal diseases
SANDERSON RALPH Molecular Regulation of the Tumor Microenvironment tumor, microenvironment, cancer, heparan sulfate, proteoglycan, heparanase, exosomes, metastasis, bone, myeloma, breast cancer, drug resistance
SCHROEDER HARRY The Development and Function of Lymphocyte Antigen Receptors. &Genetics of Primary Immune Deficiency Diseases Common Variable Immune Deficiency, Hypogammaglobulinemia, Antibody Repertoire, B cell Development, TCR repertoire, T cell development, Systemic Lupus Erythematosus, Mouse Models of Autoimmune Disease
SEGREST JERE Structural Biology of Supramolecular Assemblies (Particularly Lipoproteins and Membranes)
SERRA ROSA Mechanism of TGF-ß Action in Developmental and Disease Processes developmental biology, bone, cartilage, teeth, intervertebral disc, osteoarthrits, skeletal disease
SHEVDE-SAMANT LALITA Investigating molecular signaling mechanisms that present as fundamental aberrations in tumor cells or their immune microenvironment Tumor progression, metastasis, innate and adaptive immune microenvironment, signaling, cancer stem cells, chemoresistance, metabolism, osteolysis, Merlin, Hedgehog pathway, Wnt pathway
SIEGAL GENE Gene therapy of solid tumors, cancer biology, tumors of bone Bone Tumors, Cancer Gene Therapy, Invasion and Metastasis
SMITH PHILLIP Mucosal Immunity to Enteric Pathogens
SONG YUHUA An integrated multi-scale computational modeling and biological experimental research program to study apoptosis, cell adhesion and biomaterial design Computational Biology/Biomechanics, Mechanotransduction, Protein/Biomembrane structure and function, death receptor-mediated apoptosis, Cell adhesion, Biomaterials
STANDAERT DAVID Translational Research in Neurodegenerative Diseases Parkinsons Disease, Dystonia, Movement Disorders
STEYN ANDRIES Mechanism of Mycobacterium tuberculosis virulence tuberculosis, dormancy, persistence, virulence networks, protein-protein interaction, pathways, pathogenesis,
STRONG THERESA Identification of Tumor Antigens and Development of Cancer Vaccines gene therapy, immunotherapy, vaccine, Phase I clinical trials
SWORDS WILLIAM Opportunistic infections in the airway Biofilm, otitis media, COPD, quorum signaling, polymicrobial infection
SZTUL ELIZABETH Membrane Traffic; Protein Degradation Cystic fibrosis, membrane traffic, degradation, quality control
THEIBERT WILLIS Role of phosphoinositides in developmental neurobiology
THOMPSON SUNNIE Viral host pathogen interactions Host pathogen interactions, Mechanisms of viral translation, IRES, Polyomaviruses, Coronaviruses, Enteroviruses, Flaviviruses, Ribosome, Translational mechanisms in Cancer
TOWNES TIM Developmental Regulation of Gene Expression
VAN WAARDENBURG ROBERT Structure-Function analysis of Tyrosyl-DNA phosphodieasterase I; Developing a DNA Repair Enzyme as Therapeutic Target for Anti-Cancer Treatment Structure-function analysis, Mechanism of Action of proteins and drugs (chemotherapeutics), Drug Development for novel therapeutic targets, Post-translational modification by Ubiquitin and SUMO (Small Ubiqitin like modifier), Protein interactions
VISSCHER KRISTINA Cognitive Neuroscience attention, memory, older adults, aging, training, ongoing activity, EEG, fMRI, human neuroscience
VOLPICELLI-DALEY LAURA Cognitive impairments in Parkinson's disease and Lewy body dementias Parkinson's disease, Lewy body dementias, synuclein, tau, glucocerebrosidase, cell biology of the neuron, neurodegeneration
WADICHE JACQUES Cellular and molecular basis of synaptic transmission and neuronal organization of microcircuits glutamate transport, synaptic transmission, cerebellum
WADICHE LINDA The function of adult generated neurons and interneurons in the dentate gyrus synapse, neurogenesis, epilepsy, hippocampus, inhibition
WALTER MARK Structure, Biochemistry, and Function of Cytokines involved in Viral pathogenesis and Autoimmunity structural biology, immunology, virology, cytokine, signaling, vaccine, protein design, lupus, interferon, IL-10
WARNOCK DAVID Renal REGARDS, Fabry Registry, Inherited Disease of Electrolyte Transport Renal REGARDS, Fabry Registry, Inherited Disease of Electrolyte Transport, Chronic Kidney Disease
WEAVER CASEY Control of Adaptive Immunity by CD4 T cells
WHITE CHARLES
WHITLEY RICHARD Herpes simplex virus; varicella zoster virus; drug discovery; cytomegalovirus
WICK TIMOTHY Orthopaedic and Cardiovascular Tissue Engineering and Regenerative Medicine Tissue Engineering, Regenerative Medicine, Cartilage, Bone, Blood Vessel, Bioreactor Technology, Osteoarthritis
WILLEY CHRISTOPHER Signaling in cancer biological systems, and discovery and development of radiation modulators for cancer treatment Kinases, kinomics, MARCKS, radiation, glioma, head and neck cancer, lung cancer, signal transduction, cancer biology
XU HUI The role of IL-17 in inflammation associated tumor development T cells, dendritic cells, cytokines, tumor suppressor
YACOUBIAN TALENE Role of 14-3-3 proteins in Parkinson’s disease Parkinsons disease; Neurobiology; Molecular Genetics & Disease
YODER BRADLEY Cilia Signaling and Dysfunction in Development and Disease Cilia, cystic kidney diseases, obesity, signal transduction, cell fate determination and embryonic patterning, birth defects, mouse and C. elegans models.
YOON KARINA Molecular and cellular mechanisms of cancer metastasis neuroblastoma, metastasis, ICAM-2, actin cytoskeleton, solid tumors, animal models of cancer, cancer pharmacology
ZAJAC ALLAN Anti-Viral Immunity; T Cell Responses; Immunological Memory Immunology, Virology, Pathogenesis, Vaccines, T cells
ZAYZAFOON MAJD The Role of Calcium Signaling in the pathogenesis of disease Osteoblasts, Bone, Prostate Cancer, Osteosarcoma, Calmodulin Kinase, NFAT, AP-1, Bone metastasis, HDAC, histone acetylation, DNA methyltransferase
ZHANG JIANHUA Mechanisms and regulation of autophagy-lysosomal pathway in health and diseases Autophagy, Parkinson's Disease, Alzheimer's disease, heart disease, lysosomes, mitochondria, redox signaling