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Faculty Detail    
Name C BRUCE ALEXANDER
  
Campus Address HSB 175L Zip 6823
Phone  (205) 934-0502
E-mail  cba@uab.edu
Other websites
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Clinical Pathology  Anatomic Pathology Professor Emeritus

Graduate Biomedical Sciences Affiliations
Molecular and Cellular Pathology Program 

Biographical Sketch 
COLLEGES/POST-GRADUATE TRAINING BS 1967 Hampden-Sydney College, VA MD 1971 University of Virginia, VA 1971-73 Intern in Internal Medicine, Cleveland Metro General Hospital, OH 1975-79 Resident in Anatomic Pathology, Duke University Medical Center, NC 1976-77 NIH Fellow, Pathology, Duke University Medical Center, NC 1978-79 Fellow, Forensic Pathology, Duke University Medical Center, NC MILITARY SERVICE 1973-75 Lieutenant Commander, Medical Corps, USNR, Beaufort Naval Hospital HONORS AND AWARDS 1966 Omicron Delta Kappa 1970 Alpha Omega Alpha 1970 Raven Society 2002 Accreditation Council for Graduate Medical Education, Parker J. Palmer “Courage to Teach” Award 2011 Association of Pathology Chairs Distinguished Achievement Award in Graduate Medical Education 2012 Academy of Laboratory Physicians and Scientists Gerald Evans Award for Outstanding Leadership and Service to the Society 2013 Best Doctors in America –Birmingham Magazine December 2013 issue ACADEMIC APPOINTMENTS Professor and Vice Chair Section Head, Autopsy Pathology Residency Program Director Coursemaster, Pulmonary Module (MS1), School of Medicine Secondary Faculty, Department of Nutrition Sciences, School of Health Related Professionals Clinical Associate Professor, School of Allied Health/CLS HOSPITAL AND OTHER NON-ACADEMIC APPOINTMENTS Laboratory Medical Director, Kirklin Clinic Laboratory Chair, Credentials Committee, University of Alabama Health System Consulting Pathologist, UH Nuclear Medicine Laboratory Associate Coroner/Medical Examiner, Jefferson County, Alabama

Society Memberships
Organization Name Position Held Org Link
U.S. and Canadian Academy of Pathology     
Pulmonary Pathology Society     
National Association of Medical Examiners     
College of American Pathologists     
Association of Pathology Chairs - Program Directors Council     
American Society of Clinical Pathologists  Past President, Board of Directors   
American Pathology Foundation  Board of Directors   
American College of Chest Physicians     
American Academy of Forensic Sciences     
Alpha Omega Alpha Honor Society  Board of Directors   
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Research/Clinical Interest
Title
Description
Residency Training – Competency-based residency training in Pathology. Pulmonary Pathology - New treatment protocols for Interstitial Pulmonary Fibrosis. Forensic Pathology – Using Forensic Pathology analysis models to identify under-reported lethal forces at work upon society and drive the implementation of preventive measures.

Selected Publications 
Publication PUBMEDID
Alexander CB, Bossen EH. Peripheral couplings in human skeletal muscle. Lab Invest 1978; 39(1):17-20.   
Alexander CB, Burger PC, Goree JA. Dissecting aneurysms of the basilar artery 2 patients. Stroke 1979; 10(3):294-99.   
Hood J, Wilson ER, Alexander CB, Flint A, Ho KJ. Lymphomatoid granulomatosis manifested as a mass in the cerebellopontine angle. Arch Neurology 1982; 39(5):319-20.   
Alexander CB, McBay AJ, Hudson RP. Isopropanol and isopropanol deaths - ten years' experience. J Forensic Sci 1982;27(3):541-548.   
Alexander CB, Croker BP, Bossen EH. Dermatomyositis with associated IgA deposition. Arch Pathol Lab Med 1982;106(9):449-51.   
Vath RR, Alexander CB, Fulmer JD. The lymphocytic infiltrative lung diseases. Clinics in Chest Med 1982; 3(3):619-634.   
Ruben E, Alexander CB. Duodenal mass in a 53-year-old man 30 years after colectomy for multiple polyposis. Ala J Med Sci 1982;19(4):432-35.   
Ro YI, Alexander CB, Oh SJ. Multiple sclerosis and hypertrophic demyelinating peripheral neuropathy. Muscle Nerve 1983;6(4):312-16.   
Oh SJ, Meyers GJ, Wilson ER Jr, Alexander CB. A benign form of reducing body myopathy. Muscle Nerve 1983;6(4):278-82.   
Herrera GA, Alexander CB, de Moraes HP. Ultrastructural subtypes of pulmonary adenocarcinoma. A correlation with patient survival. Chest 1983;84(5):581-86.   
Glasgow BJ, Tift JP, Alexander CB. Spontaneous primary dissecting coronary artery aneurysm. Report of two cases. Am J Forensic Med Pathol 1984;5(2):155-59.   
Ho KJ, Herrera GA, Jones JM, Alexander CB. Small cell carcinoma of the esophagus: evidence for a unified histogenesis. Hum Pathol 1984;15(5):460-68.   
Danilewitz M, Herrera GA, Kew MC, Mendelsohn D, Barnes S, Alexander CB, Hirschowitz BI, Spenney JG. Autonomous cholesterol biosynthesis in murine hepatoma: A receptor defect with normal coated pits. Cancer 1984; 54(8):1562-8.   
Avery DM, Alexander CB, Gore H. Adenomatous endocervical hyperplasia resulting in myxometra. Am J Obstet Gynecol 1984;148(6):827-29.   
Robinson CA Jr, Ketchum CH, Grizzle WE, Hall LM, Alexander CB. An abnormal lactate dehydrogenase isoenzyme pattern in a critically ill patient. Southern Med J 1984;77(7):921-23.   
16. Tubbs PC, Robinson CA, Myszko D, Alexander CB. Evaluation of SYSMEX CC-800 automated blood cell counter. J Clin Lab Automation 1984;4:166.   
Herrera GA, Alexander CB, Jones M. Ultrastructural characterization of pulmonary neoplasms I. The role of electron microscopy in characterization of the most common epithelial neoplasms. Surv Synth Pathol Res 1984; 3:520-46.   
Alexander CB, Herrera GA, Jaffe K, Yu H. Black thyroid: clinical manifestations, ultrastructural findings and possible mechanisms. Hum Pathol 1985;16:72-78.   
Breatnach E, Luna R, Rubin E, Alexander B. Malignant melanoma presenting a mass obstructing of the common bile duct. J CT 1985;9(2):177-80.   
Herrera GA, Alexander CB, Jones M. Ultrastructural characterization of pulmonary neoplasms II. The role of electron microscopy in characterization of uncommon epithelial pulmonary neoplasms, metastatic neoplasms to and from lung and other tumors, including mesenchymal neoplasms. Surv Synth Pathol Res 1985;4:163-84.   
Fraser RG, Barnes GT, Hickey N, Luna R, Katzenstein A, Alexander CB, McElvein R, Zorn G, Sabbagh E, Robinson CA. Potential value of digital radiography. Preliminary observations on the use of dual-energy subtraction in the evaluation of pulmonary nodules. Chest 1986;89(4 Suppl):249S-252S.   
Fraser RG, Hickey NM, Niklason L, Sabbagh EA, Luna RF, Alexander CB, Robinson CA, Katzenstein A, Barnes GT. Calcification in pulmonary nodules: Detection with dual-energy digital radiography. Radiology 1986;160:595-601.   
Heimburger DC, Krumdieck CL, Alexander CB, Birch R, Dill SR, Bailey WC. Localized folic acid deficiency and bronchial metaplasia in smokers: hypothesis and preliminary report. Nutrition International 1987;3(1):54-60.   
Friedman SE, Dubovsky E, Dubovsky J, Alexander CB, Robinson CA, Sabbagh E, Barnes G, Fraser RG. The measurement of the mineral content of bone by energy subtraction digital radiography. Am J Roentgenol 1987; 149:1199-1202.   
Heimburger DC, Alexander CB, Birch R, Butterworth CE, Bailey WC, Krumdieck DL. Improvement in bronchial squamous metaplasia in smokers treated with Folate and vitamin B12. JAMA 1988; 259:1525-30. Also published in JAMA, Edition Francaise 1988;13:595-604.   
Jackson RM, Veal CF, Alexander CB, Brannen AL, Fulmer JD. Re-expansion pulmonary edema: A potential role for free radicals in its pathogenesis. Am Rev Resp Dis 1988;137(5):1165-71.   
Jackson RM, Veal CF, Alexander CB, Brannen AL, Fulmer JD. Neutrophils in re-expansion pulmonary edema. J Appl Physiol 1988; 65(1):228-34.   
Herrera GA, Turbat-Herrera EA, Alexander CB. Ultrastructural heterogeneity of pulmonary scar adenocarcinomas. A correlation with patients' survival. Ultra Pathol 1988;12:265-77.   
Berstad A, Alexander CB, Weberg R, Serck-Hanssen A, Holland S, Hirschowitz BI. Antacids reduce Campylobacter pylori colonization without healing the gastritis in patients with non-ulcer dyspepsia and erosive prepyloric changes. Gastroenterology 1988;95:619-24.   
Gammon RB, Bridges TA, Al-Nezir H, Alexander CB, Kennedy Jr, JI. Bronchiolitis obliterans organizing pneumonia associated with systemic lupus erythematosus. Chest 1992;102(4):1171-4.   
Morgan DE, Sanders C, McElvein RB, Nath H, Alexander CB. Intrapulmonary teratoma: A case report and review of the literature. J Thorac Imaging 1992;7(3):70-77.   
Singh, SP, Nath H, Pinkard NB, Alexander, CB. Bronchioloalveolar carcinoma causing pulmonary hypertension: a unique manifestation. AJR 1994;162 (1):30-32.   
Davis GG, Alexander CB, Brissie RM. A 15-year review of railway-related deaths in Jefferson County, Alabama. Am J Forensic Med Pathol 1997;18(4);363-368.   
Alexander CB, Cooper RS. Risk in the Rockies: A training exercise in risk-based managed care contracting (ASCP Check Sample exercise CC 98-4). Clinical Chemistry 1998:38(4):43-61.   
Davis GG, Alexander CB. A review of carisoprodol deaths in Jefferson Co., AL. South Med J 1998;91(8):726-730.   
Alexander CB, McDonald JM. Cost-based (Part A) pathology physician services: Origin, current spectrum, and future. Clin Lab Med 1999;19(4):783-796.   
deAndrade JA, Crow JP, Viera L, Alexander CB, Young CR, et al. Protein nitration, metabolites of reactive nitrogen species, and inflammation in lung allografts. Am J Resp Crit Care Med 2000;161(6):2035-2042.   
Alexander CB. Deconstructing disease: A pathologist’s perspective. Am Clin Lab 2000;19(3):4.   
Weill D, McGiffin DC, Zorn GL, Alexander CB, Early L, Kirklin JK, Young, KR. The utility of open lung biopsy following lung transplantation. J Heart Lung Transpl 2000;19(9):852-857.   
deAndrade JA, Christie JD, Alexander, CB, Young KR , McGiffin DC, Zorn G, Jackson RM. Association of reactive nitrogen species metabolites, myeloperoxidase , and airway inflammation in lung transplants. J Invest Med 2001;49(2):166-172.   
Alexander CB. Trends in pathology graduate medical education. Human Path 2001;32(7):671-676.   
Adams JE, Davis GG, Heidepriem RW, Alonso JE , Alexander CB. Analysis of the incidence of pelvic trauma in fatal automobile accidents. Am J Forensic Med Pathol 2002;23(2):132-136.   
Folberg R, Antonioli DA, Alexander CB. Competency-based residency training in pathology: Challenges and opportunities. Human Path 2002;33(1):3-6.   
Baldus S, Eiserich JP, Brennan ML, Jackson RM, Alexander CB, Freeman BA. Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases. Free Radical Biol Med 2002;33(7):1010-1019.   
Zorn GL Jr, McGiffin DC, Young KR Jr, Alexander CB, Weill D, Kirklin JK. Pulmonary trans-plantation for advanced bronchioloalveolar carcinoma. J Thorac Cardiovasc Surg 2003;125(1):45-8.   
Aslan M, Ryan TM, Townes TM, Coward L, Kirk MC, Barnes S, Alexander CB, Rosenfeld SS, Freeman BA. Nitric oxide-dependent generation of reactive species in sickle cell disease. J Biol Chem 2003;278(6):4194-4204.    
Adams JE, Davis GG, Alexander CB, Alonso JE. Pelvic trauma in rapidly fatal motor vehicle accidents. J of Orthopaedic Trauma 2003;17(6):406-410.   
Hagood JS, Prabhakaran P, Kumbla P, Salazar L, MacEwen MW, Barker TA, Ortiz LA, Schoeb T, Siegal GP, Alexander CB, Pardo A, Selman M. Loss of Fibroblast Thy-1 expression correlates with lung fibrogenesis. Am J Pathol 2005;167:365-379.   
Smith BR, Wells A, Alexander CB, Bovill E, Campbell S, Dasgupta A, Fung M, et. al. (for the Academy of Clinical Laboratory Physicians and Scientists). Curriculum content and evaluation of resident competency in clinical pathology (laboratory medicine): A proposal. Am J Clin Pathol 2006;125 (Suppl 1):S5-S7.   
Robboy SJ, Weintraub S, Horvath AE; Jensen BW; Alexander CB; Fody EP; Crawford JM; Clark JR; Cantor-Weinberg J, Joshi MG, Cohen MB, Prystowsky MB; Bean SM; Gupta S, Powell SZ, Speights VO; Gross DJ; Black-Schaffer WS; and additional members of the Workforce Project Work Group. Pathologist Workforce in the United States I. Development of a Predictive Model to Examine Factors Influencing Supply. Arch Pathol Lab Med. 2013 Dec;137(12):1723-32.  23738764 
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Keywords
Graduate Medical Education, Interstitial Pulmonary Fibrosis, ACGME Competencies, Forensic autopsy, Medical Autopsy