Title |
Mechanisms underlying pathological changes in visceral sensation and organ function |
Description |
I am interested in understanding the neuronal mechanisms and anatomical pathways underlying visceral sensation, and how changes in information processing lead to persistent pain and/or organ dysfunction. We utilize a combination of in vivo and in vitro techniques to study the function of distinct anatomical, neurochemical, and functional subsets of sensory neurons and their connections. Animal models of inflammation, stress, diabetes, and spinal cord injury allow us to study changes that lead to increased sensation (pain), loss of sensation, and altered organ function, with the goal of identifying novel therapeutic strategies for pain and organ dysfunction. |
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