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Faculty Detail    
Campus Address VH B140 Zip 0019
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Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Medicine  Med - Cardiovascular Disease Professor Emeritus
Center  Comprehensive Cardiovascular Ctr  Comprehensive Cardiovascular Ctr Professor Emeritus

Graduate Biomedical Sciences Affiliations
Integrative Biomedical Sciences 

Biographical Sketch 
Raymond E. Ideker was born in Oak Park, Illinois in July 1942. He received the BS degree in chemistry from the Arkansas Polytechnic College in 1965 and the MD and PhD degrees in physiology, both from the University of Tennessee in 1972 and 1974 respectively. In 1978, after completing a Pathology residency at Duke University, he joined the Departments of Medicine and Pathology at Duke, where he was Director of the Basic Arrhythmia Laboratory. In 1994, he joined the University of Alabama at Birmingham, where he is the Jeanne V. Marks Professor of Medicine, Physiologoy and Biomeidcal Engineering and where he directs the Cardiac Rhythm Management Labatory.

Research/Clinical Interest
Sudden Cardiac Death and Methods for the Prevention
The objective of this laboratory is to develop greater understanding of the basic electrophysiologic mechanisms of ventricular and atrial arrhythmias in animals and to use this information to improve the medical and surgical treatment of arrhythmias caused by coronary artery disease in humans. The animal electophysiology labotatory is equipped for all types of intact animal studies including cardiopulmonary bypass. Present studies use computerized electrical and optical mapping systems to study ventricular tachycardia and fibrillation. New techniques for the treatment of arrhythmias are developed and tested in the animal laboratory before being applied clinically.

Selected Publications 
Publication PUBMEDID
Ideker RE, Dosdall DJ. Can the Direct cardiac effects of the electrical pulses generated by the TASER X26 cause immediate or sudden cardiac arrest in normal adults? Am J Forensic Med Pathol. 2007; 28: 195-201.  17721165 
Huang J, Chang KA, Dosdall DJ, Smith WM, Ideker RE. The role of maximum rate of depolarization in predicting activation potential duration during ventricular fibrillation. Am J Physiol Heart Circ Physiol. 2007; in press.  17704288 
Tabereaux PB, Walcott GP, Rogers JM, Kim J, Dosdall DJ, Robertson PG, Killingsworth CR, Smith WM, Ideker RE. Activation patterns of Purkinje fibers during long-duration ventricular fibrillation in an isolated canine model. Circulation. 2007; 116: 1113-1119.`  17698730 
Dosdall DJ, Cheng KA, Huang J, Allison JS, Allred JD, Smith WM, Ideker RE. Transmurral and endocardial Purkinje activaiton in pigs before local myocardial activation after defibrillation shocks. Heart Rhythm. 2007; 4: 758-765.  17556199 
Ideker RE. Ventricular fibrillation: how do we put the genie back in the bottle? Heart Rhythm. 2007; 4: 665-674.  17467640 
Killingsworth CR, Walcott GP, Gamblin TL, Girouard SD, Smith WM, Ideker RE. Chronic myocardial infarction is a substrate for bradycardia-induced spontaneous tachyarrhythmias and death in conscious animals. J Cardiovasc Electrophysiol. 2006; 17: 189-197.  16533257 
Qin H, Huang J, Rogers JM, Walcott GP, Rollins DL, Smith WM, Ideker RE. Mechanisms for the maintenance of ventricular fibrillation: the nonuniform dispersion of refractoriy restitution properties, or anatomic heterogeneities? J Cardiovasc Electrophysiol. 2005; 16: 888-897.  16101633 
Nathakumar K, Walcott GP, Melnick S, Rogers JM, Kay WM, Smith WM, Ideker RE, Holman W. Epicardial organization of human ventricular fibrillaiton. Heart Rhythm 2004; 1: 14-23.  15851110 
Huang J, Zhou X, Smith WM, Ideker RE. Restitution properties during ventricular fibrillation in the in situ swine heart. Circulation. 2004; 110:3161-3167.  15533856 
Kong W, Huang J, Rollins DL, Ideker RE, Smith WM. A semi-implantable multichannel telemetry system for continuous electrical, mechanical and hemodynamic recordings in animal cardiac research. Physiol Meas. 2007; 28: 249-257.  1173222590