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Faculty Detail    
Name JIANMING TANG
 
Campus Address RPHB 624 Zip 0022
Phone  (205) 975-8630
E-mail  jtang@uabmc.edu
Other websites https://www.researchgate.net/profile/James_Tang3?ev=prf_info
     

Education
Undergraduate  Beijing Agricultural University, Beijing China    1986  B.Agr.Sci./DVM 
Graduate  The University of Queensland, Brisbane, Australia    1993  PhD 


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Medicine  Med - Infectious Diseases Professor Emeritus

Graduate Biomedical Sciences Affiliations
Cancer Biology 
Genetics, Genomics and Bioinformatics 
Immunology 
Integrative Genetics Graduate Program 

Biographical Sketch 
Jianming ‘James’ Tang (b. 1965) grew up in Hunan Province, China. He studied veterinary medicine at Beijing (China) Agricultural University (1981-1986) before pursuing a PhD degree at The University of Queensland in Brisbane, Australia (1988-1993). After post-doctoral training at the Marine Biological Laboratory (Woods Hole, MA) and at UAB Division of Geographic Medicine, he was appointed as assistant professor in 1996 and promoted to associate professor and full professor in 2004 and 2012, respectively. As documented in over 100 peer-reviewed articles in two dozen scientific journals, Dr. Tang's research has evolved from parasite immunology and molecular entomology to immunogenetics and pharmacogenetics. His current work focuses on genetic and epigenetic contributions to infection and immunity in human populations. Two ongoing projects are funded by NIH (NIAID and NIA).

Society Memberships
Organization Name Position Held Org Link
American Society for Microbiology (ASM)  Member  http://www.asm.org/ 
American Society of Histocompatibility and Immunogenetics (ASHI)  Member  http://www.ashi-hla.org/ 



Research/Clinical Interest
Title
Genetic and Epigenetic Correlates of Infection and Immunity
Description
1) Immunogenetics: population genetics; molecular phylogenetics; genotype-phenotype relationships; genetic scoring algorithms 2) Epigenetics: CpG methylation profile; methylation and cytokine gene expression; micoRNA profile 3) Public health: aging and immunologic health in persons living with HIV-1 infection

Selected Publications 
Publication PUBMEDID
51. Mónaco DC, Dilernia D, Fiore-Gartland A, Yu T, Prince J, Dennis C, Qin K, Schaeffer M, Claiborne D, Kilembe W, Tang J, Price MA, Farmer P, Gilmour J, Bansal A, Allen S, Goepfert P and Hunter E. Balance between transmitted HLA pre-adapted and non-associated polymorphisms is a major determinant of HIV-1 disease progression. J Exp Med 2016; 213(10): 2049-63. PMC5030801 (available 2017-03-19).   27551154 
52. Prentice HA, Lu H, Price MA, Sanders EJ, Anzala O, Karita E, Kamali A, Lakhi S, Allen S, Goepfert PA, Hunter E, and Gilmour J and Tang J for the International AIDS Vaccine Initiative African HIV Research Network. Dynamics and correlates of CD8 T-cell counts in primary human immunodeficiency virus type 1 infection. J Virol 2016; 90(22): 10423-30.   27630231 
53. Wiener HW, Shrestha S, Lu H, Karita E, Kilembe W, Allen S, Hunter E, Goepfert PA and Tang J*. Immunogenetic factors in early immune control of human immunodeficiency virus type 1 (HIV-1) infection: Evaluation of HLA class I amino acid variants in two African populations. Hum Immunol 2018; 79: 166-71 (ePub 12/28/2017).   29289742 
54. Erdmann N, Prentice HA, Bansal A, Wiener HW, Burkholder G, Shrestha S and Tang J*. Herpes zoster in persons living with HIV-1 infection: viremia and immunological defects are strong risk factors in the era of combination antiretroviral therapy. Front Pub Health 2018; 6: 70. doi: 10.3389/fpubh.2018.00070. PMC5857573 (ePub 03/12/2018).  29594092 

Keywords
Immunogenetics, Infectious Disease, Pharmacogenetics, Public Health