Faculty Detail   
Name TAMAS JILLING
  
Campus Address 176F 9380 Zip 0011
Phone  (205) 934-4680
E-mail  tjilling@uab.edu
Other websites
    

Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Ped - Neonatology  Ped - Neonatology Associate Professor

Biographical Sketch 
Education

1987 MD University Medical School Pécs, Hungary, Current name of school: University of Pécs, Faculty of Medicine

Postdoctoral Training

1989 – 1997: UAB, Physiology. Mentor: Kevin L. Kirk PhD

Academic Appointments

2012 – present : Associate Professor, Department of Pediatrics UAB

2008 – 2009: Research Associate Professor, Department of Pediatrics, Northwestern University

1997 – 2008: Assistant Professor, Department of Pediatrics, Northwestern University

Research/Clinical Interest
Title
Mucosal Homeostasis in Normal Development and in GI Inflammatory Diseases
Description
The intestinal epithelium undergoes rapid turnover, while it has to maintain barrier, and perform transport functions. The orderly process of turnover includes proliferation in the crypts, migration and differentiation toward the villus tip (small intestine) or toward the surface epithelium (colon), then removal by programmed cell death. This entire sequence is strongly influenced by innate and adaptive immune mechanisms and by inflammatory mediators. In turn, divergence from the normal process of turnover has profound effects on both immune and inflammatory processes in the intestine, and systemically. My research program aims to analyze the mechanisms of epithelial, immune and inflammatory interactions that underlie normal and disordered mucosal homeostasis, with particular interest in G protein-coupled receptor-mediated signaling.

Keywords
GPCR signaling, enterocyte, mucosal homeostasis, necrotizing enterocolitis, inflammatory bowel disease, colorectal cancer