Total Records: 85 |
Last Name |
First Name |
Research/Clinical Interest Title |
Keywords |
LUCIUS |
AARON |
|
|
BJORNSTI |
MARY-ANN |
|
DNA topoisomerase I, yeast genetics, cancer chemotherapeutics, TOR signaling, SUMOylation, DNA damage response, drug resistance, siRNA screening, breast cancer |
WHITE |
CHARLES |
|
|
KHARLAMPIEVA |
EUGENIA |
|
stimuli-responsive polymers, drug delivery, cell surface engineering, protein assembly at interfaces |
YOUNG |
MARTIN |
|
|
NAPIERALA |
MAREK |
|
|
HIGGINS |
N |
|
|
MORGAN |
SARAH |
|
Nutrition, osteoporosis, bone densitometry, folic acid, methotrexate |
VELU |
SADANANDAN |
|
|
NAHM |
MOON |
Adaptive and Innate Immune Responses to Pneumococci and Pneumonia Vaccines |
pneumococcus, capsule, innate immunity, pathogenesis, vaccines |
DEIVANAYAGAM |
CHAMPION |
Adherence Mechanisms of gram positive bacterial surface proteins. |
|
SONG |
YUHUA |
An integrated multi-scale computational modeling and biological experimental research program to study apoptosis, cell adhesion and biomaterial design |
Computational Biology/Biomechanics, Mechanotransduction, Protein/Biomembrane structure and function, death receptor-mediated apoptosis, Cell adhesion, Biomaterials |
RENFROW |
MATTHEW |
Analysis of Protein Glycosylation in Human Disease by High Resolution Mass Spectrometry |
Fourier transform mass spectrometry (FT-MS), protein glycosylation, IgA O-glycosylation, IgA nephropathy, proteomics, glycoproteomics |
PLACZEK |
WILLIAM |
Anti-cancer target validation and structure-based drug discovery. |
NMR spectroscopy, cancer, drug discovery, peptide synthesis, structural biology, apoptosis, signaling |
ANANTHARAMAIAH |
GATTADAHALLI |
Apolipoproteins, Amphipathic Helices and Atherosclerosis |
|
PITTLER |
STEVEN |
Basic and Translational Studies of Photoreceptor Metabolism and Retinal Degeneration |
retinitis pigmentosa, phosphodiesterase, cGMP-gated cation channel, photoreceptor, phototransduction |
BARNES |
STEPHEN |
Bile acids, polyphenols and metabolism, and their effects on protein expression and function in chronic disease |
bile acids, isoflavonoids and polyphenols, metabolomics, proteomics, mass spectrometry |
VOLPICELLI-DALEY |
LAURA |
Cognitive impairments in Parkinson's disease and Lewy body dementias |
Parkinson's disease, Lewy body dementias, synuclein, tau, glucocerebrosidase, cell biology of the neuron, neurodegeneration |
BASU |
MALAY |
Computational Genomics and Bioinformatics |
Genomics, bioinformatics, high-performance computing, grid computing, computational biology, evolution |
SCHNEIDER |
DAVID |
Control of RNA polymerase I transcription |
cancer, gene expression, RNA processing, ribosomes, transcription, drug development, enzymology |
GOLDMAN |
FREDERICK |
Creation of patient-specific gene corrected hematopoietic stem cells in inherited bone marrow failure syndromes using inducible pluripotent stem cell technology |
gene therapy, telomerase, hematopoiesis, inducible pluripotent stem cells, oxidative stress, DNA damage response pathways |
ROWE |
STEVEN |
Cystic Fibrosis Clinical and Translational Research |
cystic fibrosis, CFTR, nonsense mutations |
TOWNES |
TIM |
Developmental Regulation of Gene Expression |
|
MOBLEY |
JAMES |
Director, UAB CCC Mass Spectrometry/ Proteomics Shared Facility |
Cancer, Prostate, Pancreatic, Breast, Biomarkers, Mass Spectrometry |
KEDISHVILI |
NATALIA |
Discovery and characterization of novel enzymes that regulate the conversion of vitamin A to bioactive retinoic acid |
vitamin A, retinoic acid, oxidoreductases, development, differentiation |
CHESNOKOV |
IGOR |
DNA Replication and Cell Cycle in Eukaryotes |
DNA replication, cytokinesis, Origin Recognition Complex |
LU |
RUI |
Epigenetic Mechanisms in Cancer Initiation, Maintenance, and Drug Resistance |
Cancer, Leukemia, Epigenetics, Genomics, Chromatin, Gene regulation, Novel therapeutics |
HARTMAN |
JOHN |
Experimental models of gene interaction networks that buffer human disease using cell array phenotyping of yeast gene knockout libraries |
yeast genetics, quantitative high throughput cell array phenotyping (Q-HTCP), gene interaction networks, cellular quiescence and aging, cystic fibrosis, systems biology, drug discovery, lab automation |
HABEGGER |
KIRK |
FGF21 as mediator of the metabolic actions of glucagon & Duodenal nutrient exclusion enhances glucose metabolism via CNS regulation |
|
HASSAN |
QUAMARUL |
Gene Regulation by Non-coding RNA, Chromatin Remodeling and Modifications |
MicroRNA, Epigenetics, Bone, Tooth, Osteoblast Gene Expression, Odontoblast Gene Regulation |
HIGGINS |
N |
Genetic and Biochemical Studies of Chromosome Dynamics |
Topoisomerases, Transposition, Site-specific Recombination, Genetics |
WENDE |
ADAM |
Glucose-mediated remodeling of cardiac DNA methylation |
Diabetes, Hypertension, Exercise, Mitochondria, Metabolism, Glucose, Epigenetics, Gene expression, transcription, O-GlcNAc, protein modifications, DNA methylation, Histone modification, GLUT4, PDK2, PDK4 |
GROSS |
ALECIA |
GPCR trafficking in neurons and rhodopsin-mediated retinal degenerations |
rhodopsin, autosomal dominant retinitis pigmentosa, GPCR trafficking, rab11, nudC, MKS proteins, NPHP proteins, BBS proteins, retinal degeneration, inflammatory response in retina, cilia, protein trafficking |
FRANK |
STUART |
Growth Hormone Action and GH Receptor Structure and Function |
growth hormone, signaling, prolactin, IGF-1, growth factors |
KLUG |
CHRISTOPHER |
Hematopoietic stem cell biology, acute leukemia, and pancreatic cancer |
|
SAAD |
JAMIL |
HIV-Host Interactions and Fas-Mediated Apoptosis |
HIV, NMR, Cancer, Drug design |
CHOW |
LOUISE |
Human papillomavirus DNA replication and pathogenesis |
HPV infections and cancers |
BHATNAGAR |
SUSHANT |
Identification and characterization of novel factors in insulin secretion in obesity and type 2 diabetes |
Obesity, Type 2 Diabetes, Beta Cell Biology, Insulin Secretion, SNARE Biology, Secreted Proteins, Insulin Granule Trafficking, Tomosyn Proteins, Post-translational Modifications |
STRONG |
THERESA |
Identification of Tumor Antigens and Development of Cancer Vaccines |
gene therapy, immunotherapy, vaccine, Phase I clinical trials |
YUSUF |
NABIHA |
Innate immune mechanisms in tumor development |
toll like receptors, type I interferons, immune system, cancer, T-cells |
SMITH |
JEFFREY |
Integration of Prodeath and Prosurvival Signals by the Ubiquitin Proteasome System (UPS) |
|
OJESINA |
AKINYEMI |
Interplay of Genomic Alterations and Microbial Influences in Cancer |
cancer, infection, genomics, transcriptome, HIV, HPV, EBV, cervical, lymphoma, early detection, recurrence, precancerous, progression, mutations, microbiome, viral, RNASeq, diagnostics, therapy, global health, molecular epidemiology, women's health |
DE LANGHE |
STIJN |
Lung stem cells and their niches. |
lung stem cells, lung fibrosis, lung development, lung regeneration |
SZTUL |
ELIZABETH |
Membrane Traffic; Protein Degradation |
Cystic fibrosis, membrane traffic, degradation, quality control |
LEFKOWITZ |
ELLIOT |
Microbial Genomics and Evolution; Bioinformatics, and Clinical Informatics |
Viruses, Evolution, Genomics, Bioinformatics, Biomedical Informatics |
PATEL |
RAKESH |
Modulation of Inflammation by Reactive Species and N-glycans |
vascular, hemoglobin, red cells, Inflammation, isoflavones, Nitric oxide, nitrite, N-glycan, matrikine |
KRISHNAMURTHY |
PRASANNA |
Molecular mechanisms of cardiovascular diseases & stem cell-mediated regeneration and repair. |
Myocardial infarction, Heart failure, Stem cells, Cardiovascular regeneration and therapeutics, metabolic diseases, wound healing |
BAILEY |
SHANNON |
Molecular mechanisms of chronic alcohol and obesity induced fatty liver disease |
Molecular mechanisms of alcohol and obesity induced liver diseases; Mitochondrial dysfunction in disease; Molecular bioenergetics; Circadian biology; Functional proteomics; Nitric oxide; Free radical biology; Toxicology |
ZHENG |
X. LONG |
Molecular Mechanisms of Normal and Abnormal Blood Clotting; Inflammation and Microvascular Thrombosis; CRISPR/Cas9 Gene Editing as a Novel Therapeutic Strategy for Thrombotic Diseases |
ADAMTS13, von Willebrand factor, TTP, Arterial thrombosis, Vascular biology, Autoimmunity, and Inflammation, CRISPR/Cas9 Gene Editing |
HU |
KEJIN |
Molecular mechanisms of somatic cell reprogramming to pluripotency; self-renewal of pluripotent stem cells (PSC); Pluripotency; Epigenetics of PSC and reprogramming |
Reprogramming; embryonics stem cells; Induced pluripotent stem cells; pluripotency; epigenetics |
BRENNER |
MICHAEL |
Molecular Sudies of Astrocytes in Health and Disease |
astrocyte, GFAP, transcription, neurodegeneration, transgenic mice |
ELGAVISH |
GABRIEL |
NMR Studies of Intact Hearts |
|
NIEDERWEIS |
MICHAEL |
Novel proteins in the outer membrane of mycobacteria: Functions, structures, role in tuberculosis and applications |
tuberculosis, virulence, antibiotic resistance, membrane, proteins, transport, nanotechnology |
HOLMES |
ROSS |
Oxalate Handling and Synthesis and its Relationship to Health and Disease |
urolithiasis, oxalate, glycolate, hydroxyproline, metabolism |
BANERJEE |
RONADIP |
Pancreatic Beta-Cell Biology; Molecular mechanisms of beta-cell adaptation during pregnancy and dysregulation in gestational diabetes |
diabetes mellitus, prolactin receptor, beta-cell biology, pregnancy, transcriptional regulation |
NOVAK |
JAN |
Pathogenesis and treatments of chronic diseases, infectious diseases, cancer. IgA nephropathy. Mucosal immunology. Biomarkers. |
|
GRAY |
MICHELLE |
Pathogenesis of Huntington's Disease |
Huntington's disease, neurodegeneration, neuroscience, astrocytes |
LIMDI |
NITA |
Pharmacogenomics research and Implementation Science |
Personalized Medicine, Precision Medicine, Pharmacogenomics, Implemental Science, Pharmacoepidemiology, Pharmacoeconomics, Warfarin , Antiplatelet drugs, Antithrombotic, comparative effectiveness |
BROUILLETTE |
CHRISTIE |
Protein Structural Cooperativity and Energetics |
calorimetry, protein folding, thermodynamics, drug discovery |
KIM |
HELEN |
Proteomics of neuroprotective and chemopreventive actions of dietary phytochemicals |
neuroprotection, proteomics, protein modifications, antioxidant dietary supplements, menopause, neurogenesis |
LAPI |
SUZANNE |
Radiopharmaceuticals for Molecular Imaging |
PET, Cyclotron, radioisotopes, |
AGARWAL |
ANUPAM |
Regulation of heme oxygenase gene expression in kidney and vascular injury |
heme oxygenase, acute kidney injury, transplant nephrology, transcriptional gene regulation |
MUCCIO |
DONALD |
Retinoids for cancer prevention and therapy |
|
BELLIS |
SUSAN |
Role of glycosylation in tumor progression and metastasis |
tumorigenesis, metastasis, cancer stem cell, cell invasion, apoptosis, tumor immunology, |
WANG |
HENGBIN |
Role of Histone Modification in Chromatin and cellular Function |
epigenetics, histone modifications, ubiquitination and deubiquitination |
RAMANADHAM |
SASANKA |
Role of Lipid Mediators in Signal Transduction |
Islets, signal transduction, iPLA2, bone, protease inhibitors |
RYAN |
THOMAS |
Stem Cell Therapies in Animal Models of Human Disease |
Sickle cell anemia, thalassemia, embryonic stem cells, hemoglobin, mutagenesis, gene regulation |
PETIT |
CHAD |
Strain Dependent Structure and Function of the Influenza NS1 Protein |
influenza, nmr, ns1, structural biology, virology |
KRISHNA |
NEPALLI |
Structural Biology and Biomolecular NMR Spectroscopy |
Proteins, Structural Biology, NMR |
SEGREST |
JERE |
Structural Biology of Supramolecular Assemblies (Particularly Lipoproteins and Membranes) |
|
DOKLAND |
TERJE |
Structural biology of viral assembly and bacterial pathogenicity |
Staphylococcus, pathogenicity, virus, assembly, bacteriophages, electron microscopy, cryo-EM, crystallography, 3D reconstruction |
PREVELIGE |
PETER |
Structural Biology of Viral Assembly and Infection |
|
VASSYLYEV |
DMITRY |
Structural studies of prokaryotic transcription |
|
ALLER |
STEPHEN |
Structure and Function of Human Membrane Proteins Research/Clinical |
Membrane proteins, structure-based drug design, x-ray crystallography, biophysics, biochemistry, pharmacology, blood-brain barrier, cystic fibrosis, multi-drug resistance, drug transport, breast cancer |
WALTER |
MARK |
Structure, Biochemistry, and Function of Cytokines involved in Viral pathogenesis and Autoimmunity |
structural biology, immunology, virology, cytokine, signaling, vaccine, protein design, lupus, interferon, IL-10 |
TURNBOUGH |
CHARLES |
Structure/Function of the Bacillus anthracis Exosporium; Bacterial Gene Regulation |
anthrax, Bacillus anthracis, exosporium, E. coli, gene regulation. reiterative transcription, transcription start site switching |
CHATTOPADHYAY |
DEBASISH |
Structure-Function Analysis of Proteins |
Structural biology, Protein structure function, Malaria, Chagas' disease, Parasitic disease, Small pox, Bacterial pneumoniae |
VAN WAARDENBURG |
ROBERT |
Structure-Function analysis of Tyrosyl-DNA phosphodieasterase I; Developing a DNA Repair Enzyme as Therapeutic Target for Anti-Cancer Treatment |
Structure-function analysis, Mechanism of Action of proteins and drugs (chemotherapeutics), Drug Development for novel therapeutic targets, Post-translational modification by Ubiquitin and SUMO (Small Ubiqitin like modifier), Protein interactions |
SUDARSHAN |
SUNIL |
The Metabolic Basic of Kidney Cancer |
tumor metabolism, epigenetics, renal cancer |
SONTHEIMER |
HARALD |
The Role of Neuroglia in Brain Function and Disease |
Cell migration, brain development, primary brain tumors, glioma, astrocytes, oligodendrocytes, stem cells, regeneration |
ZHAO |
XINYANG |
The roles of protein arginine methyltransferases in abnormal hematopoiesis |
Arginine methylation, epigenetics, leukemia, stem cell, transcription |
GILES |
KEITH |
Transcripiton, Chromatin, and Pluripotentcy |
Argonatue, RNAi, insulator, nucleosomes |
HUNTER |
CHAD |
Transcriptional control of pancreatic beta cell development and adult islet cell function |
Diabetes, Transcription Factor, Coregulators, Gene Regulation, Organogenesis, Pancreas, Chromatin, Developmental Biology, Endocrinology |
THOMPSON |
SUNNIE |
Translation initiation and replication of RNA viruses |
Host pathogen interactions, Mechanisms of viral translation, IRES, Picornaviruses, Flaviviruses, Ribosome, Translational mechanisms in Cancer |
GREEN |
TODD |
Viral Transcription and Replication, Capsid Structure |
virology, structure, crystallography |