Biochemistry and Structural Biology  http://www.gbs.uab.edu  http://www.uab.edu/graduate  Back to Main
 Faculty Listing
Total Records: 88
Last Name First Name Research/Clinical Interest Title Keywords
LUCIUS AARON
BJORNSTI MARY-ANN DNA topoisomerase I, yeast genetics, cancer chemotherapeutics, TOR signaling, SUMOylation, DNA damage response, drug resistance, siRNA screening, breast cancer
WHITE CHARLES
KHARLAMPIEVA EUGENIA stimuli-responsive polymers, drug delivery, cell surface engineering, protein assembly at interfaces
YOUNG MARTIN
NAPIERALA MAREK
HIGGINS N
MORGAN SARAH Nutrition, osteoporosis, bone densitometry, folic acid, methotrexate
VELU SADANANDAN
NAHM MOON Adaptive and Innate Immune Responses to Pneumococci and Pneumonia Vaccines pneumococcus, capsule, innate immunity, pathogenesis, vaccines
DEIVANAYAGAM CHAMPION Adherence Mechanisms of gram positive bacterial surface proteins.
SONG YUHUA An integrated multi-scale computational modeling and biological experimental research program to study apoptosis, cell adhesion and biomaterial design Computational Biology/Biomechanics, Mechanotransduction, Protein/Biomembrane structure and function, death receptor-mediated apoptosis, Cell adhesion, Biomaterials
RENFROW MATTHEW Analysis of Protein Glycosylation in Human Disease by High Resolution Mass Spectrometry Fourier transform mass spectrometry (FT-MS), protein glycosylation, IgA O-glycosylation, IgA nephropathy, proteomics, glycoproteomics
PLACZEK WILLIAM Anti-cancer target validation and structure-based drug discovery. NMR spectroscopy, cancer, drug discovery, peptide synthesis, structural biology, apoptosis, signaling
ANANTHARAMAIAH GATTADAHALLI Apolipoproteins, Amphipathic Helices and Atherosclerosis
PITTLER STEVEN Basic and Translational Studies of Photoreceptor Metabolism and Retinal Degeneration retinitis pigmentosa, phosphodiesterase, cGMP-gated cation channel, photoreceptor, phototransduction
BARNES STEPHEN Bile acids, polyphenols and metabolism, and their effects on protein expression and function in chronic disease bile acids, isoflavonoids and polyphenols, metabolomics, proteomics, mass spectrometry
VOLPICELLI-DALEY LAURA Cognitive impairments in Parkinson's disease and Lewy body dementias Parkinson's disease, Lewy body dementias, synuclein, tau, glucocerebrosidase, cell biology of the neuron, neurodegeneration
BASU MALAY Computational Genomics and Bioinformatics Genomics, bioinformatics, high-performance computing, grid computing, computational biology, evolution
SCHNEIDER DAVID Control of RNA polymerase I transcription cancer, gene expression, RNA processing, ribosomes, transcription, drug development, enzymology
GOLDMAN FREDERICK Creation of patient-specific gene corrected hematopoietic stem cells in inherited bone marrow failure syndromes using inducible pluripotent stem cell technology gene therapy, telomerase, hematopoiesis, inducible pluripotent stem cells, oxidative stress, DNA damage response pathways
ROWE STEVEN Cystic Fibrosis Clinical and Translational Research cystic fibrosis, CFTR, nonsense mutations
TOWNES TIM Developmental Regulation of Gene Expression
MOBLEY JAMES Director, UAB CCC Mass Spectrometry/ Proteomics Shared Facility Cancer, Prostate, Pancreatic, Breast, Biomarkers, Mass Spectrometry
KEDISHVILI NATALIA Discovery and characterization of novel enzymes that regulate the conversion of vitamin A to bioactive retinoic acid vitamin A, retinoic acid, oxidoreductases, development, differentiation
CHESNOKOV IGOR DNA Replication and Cell Cycle in Eukaryotes DNA replication, cytokinesis, Origin Recognition Complex
LU RUI Epigenetic Mechanisms in Cancer Initiation, Maintenance, and Drug Resistance Cancer, Leukemia, Epigenetics, Genomics, Chromatin, Gene regulation, Novel therapeutics
JIANG HAO Epigenetic regulation of stem cell fate determination and tumoregenesis epigenetic regulation, histone methylation, transcription, stem cell, cancer
HARTMAN JOHN Experimental models of gene interaction networks that buffer human disease using cell array phenotyping of yeast gene knockout libraries yeast genetics, quantitative high throughput cell array phenotyping (Q-HTCP), gene interaction networks, cellular quiescence and aging, cystic fibrosis, systems biology, drug discovery, lab automation
HABEGGER KIRK FGF21 as mediator of the metabolic actions of glucagon & Duodenal nutrient exclusion enhances glucose metabolism via CNS regulation
HASSAN QUAMARUL Gene Regulation by Non-coding RNA, Chromatin Remodeling and Modifications MicroRNA, Epigenetics, Bone, Tooth, Osteoblast Gene Expression, Odontoblast Gene Regulation
HIGGINS N Genetic and Biochemical Studies of Chromosome Dynamics Topoisomerases, Transposition, Site-specific Recombination, Genetics
WENDE ADAM Glucose-mediated remodeling of cardiac DNA methylation Diabetes, Hypertension, Exercise, Mitochondria, Metabolism, Glucose, Epigenetics, Gene expression, transcription, O-GlcNAc, protein modifications, DNA methylation, Histone modification, GLUT4, PDK2, PDK4
GROSS ALECIA GPCR trafficking in neurons and rhodopsin-mediated retinal degenerations rhodopsin, autosomal dominant retinitis pigmentosa, GPCR trafficking, rab11, nudC, MKS proteins, NPHP proteins, BBS proteins, retinal degeneration, inflammatory response in retina, cilia, protein trafficking
FRANK STUART Growth Hormone Action and GH Receptor Structure and Function growth hormone, signaling, prolactin, IGF-1, growth factors
KLUG CHRISTOPHER Hematopoietic stem cell biology, acute leukemia, and pancreatic cancer
SAAD JAMIL HIV-Host Interactions and Fas-Mediated Apoptosis HIV, NMR, Cancer, Drug design
CHOW LOUISE Human papillomavirus DNA replication and pathogenesis HPV infections and cancers
BHATNAGAR SUSHANT Identification and characterization of novel factors in insulin secretion in obesity and type 2 diabetes Obesity, Type 2 Diabetes, Beta Cell Biology, Insulin Secretion, SNARE Biology, Secreted Proteins, Insulin Granule Trafficking, Tomosyn Proteins, Post-translational Modifications
STRONG THERESA Identification of Tumor Antigens and Development of Cancer Vaccines gene therapy, immunotherapy, vaccine, Phase I clinical trials
YUSUF NABIHA Innate immune mechanisms in tumor development toll like receptors, type I interferons, immune system, cancer, T-cells
SMITH JEFFREY Integration of Prodeath and Prosurvival Signals by the Ubiquitin Proteasome System (UPS)
OJESINA AKINYEMI Interplay of Genomic Alterations and Microbial Influences in Cancer cancer, infection, genomics, transcriptome, HIV, HPV, EBV, cervical, lymphoma, early detection, recurrence, precancerous, progression, mutations, microbiome, viral, RNASeq, diagnostics, therapy, global health, molecular epidemiology, women's health
DE LANGHE STIJN Lung stem cells and their niches. lung stem cells, lung fibrosis, lung development, lung regeneration
SZTUL ELIZABETH Membrane Traffic; Protein Degradation Cystic fibrosis, membrane traffic, degradation, quality control
LEFKOWITZ ELLIOT Microbial Genomics and Evolution; Bioinformatics, and Clinical Informatics Viruses, Evolution, Genomics, Bioinformatics, Biomedical Informatics
PATEL RAKESH Modulation of Inflammation by Reactive Species and N-glycans vascular, hemoglobin, red cells, Inflammation, isoflavones, Nitric oxide, nitrite, N-glycan
KRISHNAMURTHY PRASANNA Molecular mechanisms of cardiovascular diseases & stem cell-mediated regeneration and repair. Myocardial infarction, Heart failure, Stem cells, Cardiovascular regeneration and therapeutics, metabolic diseases, wound healing
BAILEY SHANNON Molecular mechanisms of chronic alcohol and obesity induced fatty liver disease Molecular mechanisms of alcohol and obesity induced liver diseases; Mitochondrial dysfunction in disease; Molecular bioenergetics; Circadian biology; Functional proteomics; Nitric oxide; Free radical biology; Toxicology
ZHENG X. LONG Molecular Mechanisms of Normal and Abnormal Blood Clotting; Inflammation and Microvascular Thrombosis; CRISPR/Cas9 Gene Editing as a Novel Therapeutic Strategy for Thrombotic Diseases ADAMTS13, von Willebrand factor, TTP, Arterial thrombosis, Vascular biology, Autoimmunity, and Inflammation, CRISPR/Cas9 Gene Editing
HU KEJIN Molecular mechanisms of somatic cell reprogramming to pluripotency; self-renewal of pluripotent stem cells (PSC); Pluripotency; Epigenetics of PSC and reprogramming Reprogramming; embryonics stem cells; Induced pluripotent stem cells; pluripotency; epigenetics
BRENNER MICHAEL Molecular Sudies of Astrocytes in Health and Disease astrocyte, GFAP, transcription, neurodegeneration, transgenic mice
ELGAVISH GABRIEL NMR Studies of Intact Hearts
NIEDERWEIS MICHAEL Novel proteins in the outer membrane of mycobacteria: Functions, structures, role in tuberculosis and applications tuberculosis, virulence, antibiotic resistance, membrane, proteins, transport, nanotechnology
HOLMES ROSS Oxalate Handling and Synthesis and its Relationship to Health and Disease urolithiasis, oxalate, glycolate, hydroxyproline, metabolism
BANERJEE RONADIP Pancreatic Beta-Cell Biology; Molecular mechanisms of beta-cell adaptation during pregnancy and dysregulation in gestational diabetes diabetes mellitus, prolactin receptor, beta-cell biology, pregnancy, transcriptional regulation
NOVAK JAN Pathogenesis and treatments of chronic diseases, infectious diseases, cancer. IgA nephropathy. Mucosal immunology. Biomarkers.
GRAY MICHELLE Pathogenesis of Huntington's Disease Huntington's disease, neurodegeneration, neuroscience, astrocytes
LIMDI NITA Pharmacogenomics research and Implementation Science Personalized Medicine, Precision Medicine, Pharmacogenomics, Implemental Science, Pharmacoepidemiology, Pharmacoeconomics, Warfarin , Antiplatelet drugs, Antithrombotic, comparative effectiveness
CHEN CHING-YI Post-transcriptional regulation of adipocyte lipid metabolism and type 2 diabetes Post-transcriptional regulation, RNA-binding protein, Adipocyte function
BROUILLETTE CHRISTIE Protein Structural Cooperativity and Energetics calorimetry, protein folding, thermodynamics, drug discovery
KIM HELEN Proteomics of neuroprotective and chemopreventive actions of dietary phytochemicals neuroprotection, proteomics, protein modifications, antioxidant dietary supplements, menopause, neurogenesis
LAPI SUZANNE Radiopharmaceuticals for Molecular Imaging PET, Cyclotron, radioisotopes,
AGARWAL ANUPAM Regulation of heme oxygenase gene expression in kidney and vascular injury heme oxygenase, acute kidney injury, transplant nephrology, transcriptional gene regulation
MUCCIO DONALD Retinoids for cancer prevention and therapy
BELLIS SUSAN Role of glycosylation in tumor progression and metastasis tumorigenesis, metastasis, cancer stem cell, cell invasion, apoptosis, tumor immunology,
WANG HENGBIN Role of Histone Modification in Chromatin and cellular Function epigenetics, histone modifications, ubiquitination and deubiquitination
RAMANADHAM SASANKA Role of Lipid Mediators in Signal Transduction Islets, signal transduction, iPLA2, bone, protease inhibitors
RYAN THOMAS Stem Cell Therapies in Animal Models of Human Disease Sickle cell anemia, thalassemia, embryonic stem cells, hemoglobin, mutagenesis, gene regulation
PETIT CHAD Strain Dependent Structure and Function of the Influenza NS1 Protein influenza, nmr, ns1, structural biology, virology
SHA BINGDONG Structural and functional studies of proteins involved in protein folding and translocations
KRISHNA NEPALLI Structural Biology and Biomolecular NMR Spectroscopy Proteins, Structural Biology, NMR
SEGREST JERE Structural Biology of Supramolecular Assemblies (Particularly Lipoproteins and Membranes)
DOKLAND TERJE Structural biology of viral assembly and bacterial pathogenicity Staphylococcus, pathogenicity, virus, assembly, bacteriophages, electron microscopy, cryo-EM, crystallography, 3D reconstruction
PREVELIGE PETER Structural Biology of Viral Assembly and Infection
VASSYLYEV DMITRY Structural studies of prokaryotic transcription
ALLER STEPHEN Structure and Function of Human Membrane Proteins Research/Clinical Membrane proteins, structure-based drug design, x-ray crystallography, biophysics, biochemistry, pharmacology, blood-brain barrier, cystic fibrosis, multi-drug resistance, drug transport, breast cancer
WALTER MARK Structure, Biochemistry, and Function of Cytokines involved in Viral pathogenesis and Autoimmunity structural biology, immunology, virology, cytokine, signaling, vaccine, protein design, lupus, interferon, IL-10
TURNBOUGH CHARLES Structure/Function of the Bacillus anthracis Exosporium; Bacterial Gene Regulation anthrax, Bacillus anthracis, exosporium, E. coli, gene regulation. reiterative transcription, transcription start site switching
CHATTOPADHYAY DEBASISH Structure-Function Analysis of Proteins Structural biology, Protein structure function, Malaria, Chagas' disease, Parasitic disease, Small pox, Bacterial pneumoniae
VAN WAARDENBURG ROBERT Structure-Function analysis of Tyrosyl-DNA phosphodieasterase I; Developing a DNA Repair Enzyme as Therapeutic Target for Anti-Cancer Treatment Structure-function analysis, Mechanism of Action of proteins and drugs (chemotherapeutics), Drug Development for novel therapeutic targets, Post-translational modification by Ubiquitin and SUMO (Small Ubiqitin like modifier), Protein interactions
SUDARSHAN SUNIL The Metabolic Basic of Kidney Cancer tumor metabolism, epigenetics, renal cancer
SONTHEIMER HARALD The Role of Neuroglia in Brain Function and Disease Cell migration, brain development, primary brain tumors, glioma, astrocytes, oligodendrocytes, stem cells, regeneration
ZHAO XINYANG The roles of protein arginine methyltransferases in abnormal hematopoiesis Arginine methylation, epigenetics, leukemia, stem cell, transcription
GILES KEITH Transcripiton, Chromatin, and Pluripotentcy Argonatue, RNAi, insulator, nucleosomes
HUNTER CHAD Transcriptional control of pancreatic beta cell development and adult islet cell function Diabetes, Transcription Factor, Coregulators, Gene Regulation, Organogenesis, Pancreas, Chromatin, Developmental Biology, Endocrinology
THOMPSON SUNNIE Translation initiation and replication of RNA viruses Host pathogen interactions, Mechanisms of viral translation, IRES, Picornaviruses, Flaviviruses, Ribosome, Translational mechanisms in Cancer
GREEN TODD Viral Transcription and Replication, Capsid Structure virology, structure, crystallography