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Faculty Detail    
Name BIN REN
Associate Professor in Vascular Surgery/Biomedical Engineering
 
Campus Address BDB 503 Zip 0000
Phone
E-mail  bren98@uab.edu
Other websites Ren Lab @UAB
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Surgery   Surgery - Gen Surg Vascular Section Associate Professor
Center  Comprehensive Cancer Center  Comprehensive Cancer Center Associate Professor
Center  Comprehensive Diabetes Center  Comprehensive Diabetes Center Associate Professor
Center  Nutrition Sciences   Nutrition Obesity Res Ctr (NORC) Associate Professor

Graduate Biomedical Sciences Affiliations
Cancer Biology 
Cellular and Molecular Biology Program 
Engineering 
Genetics and Genomic Sciences 
Hughes Med-Grad Fellowship Program 
Medical Scientist Training Program 
Molecular and Cellular Pathology Program 
Neuroscience Graduate Program 

Biographical Sketch 
Immediately after graduation from University of Science and Technology of China (USTC), Dr. Ren obtained a postdoctoral fellowship from Harvard Medical School to study cancer biology and angiogenesis under the mentorship of Drs. Roya Khosravi-far and Jack Lawler. He continued his angiogenesis studies at Dartmouth College Geisel School of Medicine and the Cleveland Clinic, respectively working with Drs. Michael Simons and Roy Silverstein. These experiences guided his focus toward understanding how angiogenic signaling regulates angiogenesis and arteriogenesis in tumor progression and under ischemic conditions. His long-term goal is to ascertain key molecular targets to effectively inhibit or stimulate angiogenesis and feeding blood vessels. He anticipates that the studies in his Laboratory of Molecular and Vascular Pathobiology will yield a new paradigm for angiogenesis and aid in discovery of innovative therapeutic approaches to targeting key regulators of functional angiogenesis, which may lead to the translation into improved therapeutic strategies in patients with cancer, ischemic heart and vascular disease, diabetes or Alzheimer’s disease.



Research/Clinical Interest
Title
Epigenetic and Transcriptional Regulation of Functional Angiogenesis and Arteriogenesis in Cancer, Heart and Vascular Diseases, Alzheimer's Disease and Diabetes.
Description
Biomedical Research by using innovative cellular models, genetically engineered animal models and a variety of disease model systems.

Keywords
Endothelial cells, Angiogenesis, Arteriogenesis, Molecular and cellular biology, Cancer, Ischemic heart and vascular diseases, Diabetes, Alzherimer's disease