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Faculty Detail    
Name MICHAEL GRAY
 
Campus Address BBRB 656 Zip 2170
Phone  (20-5) -293
E-mail  mjgray@uab.edu
Other websites lab website
     

Education
Undergraduate  Cornell University    1999  B.S. 
Graduate  University of California - Davis    2001  M.S. 
Graduate  University of Wisconsin - Madison    2010  Ph.D. 
Fellowship  University of Michigan    2015  postdoctoral fellowship 


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Microbiology  Microbiology Assistant Professor

Graduate Biomedical Sciences Affiliations
Biochemistry and Molecular Genetics Program 
Cell, Molecular, & Developmental Biology 
Genetics, Genomics and Bioinformatics 
Immunology 
Microbiology 
Pathobiology and Molecular Medicine 



Research/Clinical Interest
Title
Bacterial responses to oxidative stress
Description
I am interested in how bacteria sense and respond to inflammatory oxidants, especially reactive chlorine species, with a particular focus on probiotic and symbiotic bacteria.

Selected Publications 
Publication PUBMEDID
Rudat AK, Pokhrel A, Green TJ, Gray MJ. Mutations in Escherichia coli Polyphosphate Kinase That Lead to Dramatically Increased In Vivo Polyphosphate Levels. J Bacteriol. 2018 Feb 23;200(6). pii: e00697-17.  29311274 
Gray, M.J. and Jakob, U. Oxidative stress protection by polyphosphate: new roles for an old player. Curr Opin Microbiol 2015; 24: 1-6.   25589044 
Gray, M.J., Wholey, W.-Y., Cremers, C.M., Wagner, N.O., Mueller-Schickert, A., Hock, N.T., Krieger, A.G., Smith, E.M., Bender, R.A., Bardwell, J.C.A., and Jakob, U. Polyphosphate is a Primordial Chaperone. Mol Cell 2014; 53(5): 689-699.  24560923 
Parker, B.W., Schwessinger, E.A., and Jakob, U, and Gray, M.J. The RclR protein is a reactive chlorine-specific transcription factor in Escherichia coli. J Biol Chem 2013; 288(45): 32574-32584.   24078635 
Gray, M.J., Wholey, W.-Y., and Jakob, U. Bacterial responses to reactive chlorine species. Annu Rev Microbiol 2013; 67: 141-60.   23768204 

Keywords
microbiota, redox, stress, probiotics, reactive chlorine, inflammation