Undergraduate |
Knox College |
|
2000 |
BA in Biochemistry and Biology |
Graduate |
Washington University in St. Louis |
|
2006 |
PhD in Molecular Cellular Biology |
Fellowship |
University of Utah |
|
2013 |
Postdoctoral studies |
|
Appointment Type |
Department |
Division |
Rank |
Primary |
Pathology |
Molecular & Cellular Pathology |
Associate Professor |
Secondary |
Biomedical Engineering |
Biomedical Engineering |
Assistant Professor |
Center |
Center for AIDS Research |
Center for AIDS Research |
Associate Professor |
Center |
Comprehensive Cancer Center |
Comprehensive Cancer Center |
Associate Professor |
Center |
Comprehensive Cardiovascular Ctr |
Comprehensive Cardiovascular Ctr |
Associate Professor |
Center |
Comprehensive Diabetes Center |
Comprehensive Diabetes Center |
Associate Professor |
Center |
General Clinical Research Center |
Ctr for Clinical & Translational Sci |
Associate Professor |
Center |
Cell, Developmntl, & Integrative Biology |
Ctr for Exercise Medicine |
Associate Professor |
Center |
General Clinical Research Center |
Minority Health & Research Center |
Associate Professor |
Center |
Nutrition Sciences |
Nutrition Obesity Res Ctr (NORC) |
Associate Professor |
|
Biochemistry and Structural Biology |
Cell, Molecular, & Developmental Biology |
Genetics, Genomics and Bioinformatics |
Molecular and Cellular Pathology Program |
Pathobiology and Molecular Medicine |
|
Publication |
PUBMEDID |
Please use PubMed link under "Other websites" above for full list of published manuscripts. Here is a selection of the most relevant 10 of 58 in print or press. |
N/A |
Pepin ME, Ha CM, Crossman DK, Litovsky SH, Varambally S, Barchue JP, Pamboukian SV, Diakos NA, Drakos SG, Pogwizd SM and Wende AR. Genome-wide DNA methylation changes associated with cardiac transcriptional profiles in human ischemic heart failure. Laboratory Investigation, 99(3):371-386, 2019. (COVER ARTICLE) |
30089854 |
Koentges C*, Pepin ME*, Müsse C, Pfeil K, Viteri Alvarez SV, Hoppe N, Hoffmann MM, Odening KE, Sossalla S, Zirlik A, Hein L, Bode C, Wende AR# and Bugger H#. Gene expression analysis to identify mechanisms underlying heart failure susceptibility in mice and humans. Basic Research in Cardiology, 113(1):1-17, 2018. |
29288409 |
Wende AR, Kim J, Holland W, Wayment BE, O'Neill BT, Tuinei J, Brahma MK, Pepin ME, McCrory MA, Luptak I, Halade GV, Litwin SE, Abel ED. Glucose transporter 4 (GLUT4) deficient hearts develop maladaptive hypertrophy in response to physiologic or pathologic stresses. American Journal of Physiology. Heart and Circulatory Physiology, 313(6):H1098-H1108, 2017. |
28822962 |
Wende AR. Post-translational modifications of the cardiac proteome in diabetes and heart failure. Proteomics Clinical Applications, 10(1):25-38, 2016. |
26140508 |
Wende AR, Brahma MK, McGinnis GR and Martin ME. Metabolic origins of heart failure. Journal of the American College of Cardiology, 2(3):297-310, 2017. |
28944310 |
Wende AR*, O’Neill BT*, Bugger H, Riehle C, Tuinei J, Buchanan J, Tsushima K, Wang L, Caro P, Guo A, Sloan C, Kim BJ, Wang X, Pereira RO, McCrory MA, Nye BG, Benavides GA, Darley-Usmar VM, Shioi T, Weimer B and Abel ED. Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes. Molecular and Cellular Biology, 35(5):831-846, 2015. |
25535334 |
Riehle C, Wende AR, Sena S, Pires KM, Pereira RO, Zhu Y, Bugger H, Frank D, Bevins J, Chen D, Perry CN, Dong XC, Valdez S, Sheng X, Weimer BC, Gottlieb RA, White MF and Abel ED. Insulin receptor substrates are required for suppressing neonatal autophagy in the heart. The Journal of Clinical Investigation, 123(12):5319-5333, 2013. |
24177427 |
Wende AR, Schaeffer PJ, Parker GL, Zechner C, Han DH, Chen MM, Hancock CR, Lehman JJ, Huss JH, McClain DA, Holloszy JO and Kelly DP. A role for the transcriptional coactivator PGC-1alpha in muscle refueling. The Journal of Biological Chemistry, 282(50):36642-36651, 2007. |
17932032 |
Wende AR, Huss JM, Schaeffer PJ, Giguère V and Kelly DP. PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: A mechanism for transcriptional control of muscle glucose metabolism. Molecular and Cellular Biology, 25(24):10684-10694, 2005. |
16314495 |
Baar K, Wende AR, Jones TE, Marison M, Nolte LA, Chen M, Kelly DP and Holloszy JO. Adaptations of muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. The FASEB Journal, 16(14):1879-1886, 2002. (CITED >1,000 TIMES) |
12468452 |
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