Appointment Type |
Department |
Division |
Rank |
Center |
Center for AIDS Research |
Center for AIDS Research |
Associate Professor |
Center |
Comp Arthritis, MSK, Bone & Autoimmunity Ctr |
Comp Arthritis, MSK, Bone & Autoimmunity Ctr |
Associate Professor |
Center |
Comprehensive Cancer Center |
Comprehensive Cancer Center |
Associate Professor |
Secondary |
Dermatology |
Dermatology |
Associate Professor |
Center |
General Clinical Research Center |
Minority Health & Research Center |
Associate Professor |
Center |
Nutrition Sciences |
Nutrition Obesity Res Ctr (NORC) |
Associate Professor |
Primary |
Nutrition Sciences |
Nutrition Sciences Chair Office |
Associate Professor |
Center |
Pathology |
Cell Adhesion & Matrix Research Center |
Associate Professor |
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Cell, Molecular, & Developmental Biology |
Medical Scientist Training Program |
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Organization Name |
Position Held |
Org Link |
American Association for Cancer Research |
Member |
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American Society of Matrix Biology |
Member |
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American Society of Nutrition |
Member |
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Society of Investigative Dermatology |
Member |
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Publication |
PUBMEDID |
Chang PL, Hsieh YH, Wang CC, Juliana MM, Tsuruta Y, Timares L, Elmets C, Ho KJ: Osteopontin facilitates ultraviolet B-induced squamous cell carcinoma development. J Dermatol Sci, 75(2): 121-32, 2014 (Editor’s Choice).
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Hsieh YH, van der Heyde H, Oh ES, Guan JL, Chang PL. Osteopontin mediates tumorigenic transformation of a preneoplastic murine cell line by suppressing anoikis: an Arg-Gly-Asp-dependent-focal adhesion kinase-caspase-8 axis. Molecular Carcinogenesis, Epub Nov 19th, 2013. |
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Hsieh YH, Juliana MM, Ho KJ, Kuo, HA, van der Heyde, H, Elmets C, Chang PL. Host-derived osteopontin maintains an acute inflammatory response in the microenvironment to suppress early progression of extrinsic cancer cells. Int. J Cancer,131:322-33,2012,Epub Aug 8, 2011 PMID: 21826648 |
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Hsieh YH, Juliana MM, and Chang PL. Establishment and characterization of an osteopontin-null cutaneous squamous cell carcinoma cell line. In Vitro Cellular & Developmental Biology-Animal. 46:87-91, 2010. Epub, 2009. PMID: 19915934 |
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Chang PL, Harkins L, Hsieh YH, Hicks P, Sappayatosok K, Yodsanga S, Swasdison S, Chambers AF, Elmets CA, Ho KJ. Osteopontin in normal skin and non-melanoma skin tumors. J Histochem Cytochem. 2008 Jan;56(1):57-66. Epub 2007 Oct 15. |
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Hsieh, Y.H., Juliana, M.M., Hicks, P., Feng, G., Elmets, G., Liaw, L., Chang, P.L. Papilloma development is delayed in osteopontin null mice: implicating an antiapoptosis role for osteopontin, Cancer Research, 66:711—7127, 2006. |
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Chang, P.L., Blair, H.C., Zhao, X., Chien, Y.W., Chen, D.T., Tilden, A.B., Chang, Z., Cao, X., Faye-Petersen, O.M. and Hicks, P. Comparison of fetal and adult marrow stromal cells in osteogenesis with and without glucocorticoids. Connective Tissue Research, 47:67-76, 2006. |
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Feng, G., Ohmori , Y.and Chang, P.L. Production of Chemokine CXCL1/KC by Okadaic Acid through the Nuclear Factor-ƒÛB Pathway. Advance Access publication July 2005, Carcinogenesis 27:43-52-2006. |
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Kilpadi, K.L., Sawyer, A.A., Prince, C.W., Chang, P.L. and Bellis, S. Primary human marrow stromal cells and Saos-2 cells use different mechanism to adhere to hydroxyapatite. J Biomed Mater Res. 68A(2):273-285, 2004. |
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Feng, G., Hicks, P. and Chang, P.L. Differential expression of mammalian and viral-promoter driven gene in adherent versus suspension cells. In Vitro Cell. Dev. Biol.-Animal 39:420-423, 2003. |
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Chang, P.L., Cao, M. and Hicks, P. Osteopontin Induction is required for tumor promoter-induced transformation of preneoplastic mouse cells. Carcinogenesis 24:1749-1758, 2003. |
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Ding, Q., Steward, J.Jr., Prince, C.W., Chang, P.L., Trikha, M., Han, X., Grammer, R. and Gladson, C.L. Osteopontin expression in the normal brain promotes malignant astrocytomas cell migration: differences in integrin signaling during cell adhesion to osteopontin versus vitronectin. Cancer Res 62:5336-5343, 2002. |
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Chang, P-L., Tucker, M.A., Hicks, P., Prince, C.W. Novel protein kinase C isoforms and mitogen-activated kinase kinase mediate phorbol-ester-induced osteopontin expression. International Journal of Biochemistry & Cell Biology 34:1142-1151, 2002. |
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Moore, N.S., Wang-Johanning, F., Chang, P.L., Johanning, G.L. Omega-3 fatty acids decrease protein kinase expression in human breast cancer cells. Breast Cancer Research and Treatment, 67:279-283,2001. |
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Kilpadi, K.,Chang, PL, Bellis, S. Hydroxylapatite binds more serum proteins, purified integrins and osteoblast precursor cells than titanium or steel. Journal of Biomedical Materials Research 57:258-267, 2001. |
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Petrow, P.K., Hummel, K.M., Schedel, J. Franz, J.K., Klein, C.L., Muller-Ladner, U., Kriegsmann, J., Chang, P.-L., Prince, C.W., Gay, R.E. and Gay, S. Expression of osteopontin messenger RNA and protein in rheumatoid arithritis. Arthritis and Rheumatism 43:1597-15605, 2000 |
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Gladson, CL, Stewart, J., Olman, M.A., Chang, P.L., Schnapp, L, Grammer, J.R., and Benvenista, E.N. Attachment of primary neonatal rat astrocytes to vitronectin is mediated by integrin ƒÑvƒÒ5 and ƒÑ8ƒÒ1: modulation by the type 1 plasminogen activator inhibitor. Neuroscience Letters 283:157-161, 2000 |
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Chang, P.L., and Chambers, A.F. Transforming JB6 cells exhibit enhanced integrin-mediated adhesion to osteopontin. Journal of Cellular Biochemistry 78:8-23, 2000 |
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