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Faculty Detail    
Name JANE R SCHWEBKE
 
Campus Address ZRB 239 Zip 0007
Phone  (20-5) -665
E-mail  schwebke@uab.edu
Other websites
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Medicine  Med - Infectious Diseases Professor
Secondary  Epidemiology  Epidemiology Professor
Center  Center for AIDS Research  Center for AIDS Research Professor
Center  General Clinical Research Center  Minority Health & Research Center Professor

Biographical Sketch 
Dr. Jane Schwebke is a Professor of Medicine who also has a joint appointment in Epidemiology in the UAB School of Public Health and serves as Medical Director of the Jefferson County Department of Health STD Clinic.



Research/Clinical Interest
Title
Description
Dr. Schwebke’s laboratory has emphasized microbiologic studies of vaginal flora in women including Trichomonas vaginalis and bacterial vaginosis (BV). Dr. Schwebke’s recent work has included the development of new methodologies for evaluation of changes in vaginal flora over time, new perspectives on the origins and management of women with BV, and evaluation of new diagnostic tests (culture methods, PCR) for trichomoniasis. She has also recently guided development of laboratory efforts to evaluate and carry out surveillance for nosocomial infections caused by resistant bacteria within UAB Hospital. Major ongoing research efforts include studies of interactions between BV and risk for other STDs; characterization of the make-up and shifts in normal vaginal flora in women; prevention of recurrent BV; and the epidemiology and optimal management strategies for trichomoniasis in males. Her research is funded through the UAB STD CRC (E.W. Hook, PI, J.R. Schwebke Co-PI); and 3 funded RO-1 grants (J.R. Schwebke, P.I.).

Selected Publications 
Publication PUBMEDID
Schwebke, JR and Desmond, R. Risk factors for bacterial vaginosis in women at high risk for STDs. Sex Transm Dis 2005; 32:654-8

Schwebke JR. Trichomoniasis in adolescents: a marker for lack of public health response to the epidemic of sexually transmitted diseases in the United States. J Infect Dis 2005; 192:2036-8.

Nansel TR, Riggs M, Yu KF, Andrews WW, Schwebke JR, Klebanoff MA. The association of psychosocial stress and bacterial vaginosis in a longitudinal cohort. Am J Obstet Gynecol 2006; 194: 381-6.


Lichtenstein B, Schwebke JR. Partner notification methods for African American men being tested for trichomoniasis: a consideration of main men, second hitters and third players. Med Anthrop Quarterly 2005;19:383-401.

Ross SA, Novak Z, Ashrith G, Rivera LB, Hedges S, Schwebke JR, Boppana S. The association between genital tract Cytomegalovirus infection and bacterial vaginosis. J Infect Dis 2005; 192:1727-30.

Sobel JD, Ferris D, Schwebke J, Nyirjesy P, Wiesenfeld H, Peipert J, Soper D, Ohmit S, Hillier S. Suppressive maintenance antibacterial therapy with 0.75% metronidazole vaginal gel to prevent recurrent bacterial vaginosis. Am J Obstet Gynecol 2006; 194: 1283-9.

Hobbs MM, Lapple DM, Lawing L, Schwebke JR, Cohen MS, Swygard H, Atashili J, Leone PA, Miller WC, Seña AC. Methods for detection of Trichomonas vaginalis in the male partners of infected women: implications for control of trichomoniasis. J Clin Microbiol 2006; 44:3994-99.

Seña AC, Miller WC, Hobbs MM, Schwebke JR, Leone PA, Swygard H, Atashili J, Cohen MS. Trichomonas vaginalis infection in male sexual partners: implications for diagnosis, treatment and prevention. Clin Infect Dis 2007; 44:13-22.

Klebanoff MA, Andrews WW, Yu, KF, Brotman RM, Nansel TR, Zhang J, Cliver SP, Schwebke JR. A pilot study of vaginal flora changes with randomization to cessation of douching. Sex Transm Dis 2006; 33: 610-13.

Hedges SR, Barrientes F, Desmond RA, Schwebke JR. Local and systemic cytokine levels in relation to changes in vaginal flora. J Infect Dis 2006; 193:556-62.

Schwebke JR and Desmond RA. A randomized trial of the duration of therapy with metronidazole plus or minus azithromycin for treatment of symptomatic bacterial vaginosis. Clin Infect Dis 2007; 44:213-9.

Schwebke JR and Barrientes FJ. Prevalence of Trichomonas vaginalis isolates with resistance to metronidazole and tinidazole. Antimicrob Agents Chemo 2006; 50:4209-10.

Schwebke JR and Desmond R. A randomized trial of metronidazole in asymptomatic BV to prevent acquisition of STDs. In Press Am J Ob Gyn