Graduate |
Rutgers University |
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1994 |
PhD in Biochemistry and Molecular Biology |
Fellowship |
Emory University School of Medicine |
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2005 |
Board certification in Clinical Biochemical Genetics |
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American Board of Medical Genetics (Clinical Biochemical Genetics) |
2005 |
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Appointment Type |
Department |
Division |
Rank |
Center |
Nephrology Research & Training Center |
Nephrology Research & Training Center |
Professor |
Center |
Ctr for Clinical & Translational Sci |
Ctr for Clinical & Translational Sci |
Professor |
Primary |
Clinical Genetics |
Clinical Genetics |
Professor |
Center |
Civitan International Research Center |
Civitan International Research Center |
Professor |
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Genetics and Genomic Sciences |
Integrative Genetics Graduate Program |
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Organization Name |
Position Held |
Org Link |
American College of Medical Genetics (ACMG) |
Active Member |
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American Board of Medical Genetics and Genomics (ABMGG) |
Board of Directors |
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Accrediatation Council for Graduate Medical Education (ACGME) |
Medical Genetics Residency Review Committee |
|
American Society of Human Genetics (ASHG) |
Past Member |
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Southeast Regional Genetics Group (SERGG) |
President |
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Association of Professors of Human and Medical Genetics (APHMG) |
Workgroup Chair |
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Publication |
PUBMEDID |
Sharer, J. D. (2015) Amino Acids and Disorders of Amino Acid Metabolism. pp. 136 – 147. In Encyclopedia of Neurological Sciences, 2nd edition (M.J. Aminoff and R.B. Daroff, eds). Elsevier. |
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Kim, T., Moore, J. F., Sharer, J. D., Yang, K., Wood, P. A., and Yang, Q. (2014) Carnitine palmitoyltransferase 1b deficient mice develop severe insulin resistance after prolonged high fat diet feeding. J. Diabetes Metab. 5: 1000401 |
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Askenazi, D. J., Moore, J. F., Fineberg, N., Koralkar, R., Clevenger, S., and Sharer, J. D. (2014) Comparison of methods, storage conditions and time to analysis of serum and urine creatinine measured from microsamples by liquid chromatography mass spectrometry (LC/MS) vs. Jaffe. J. Clin. Lab Anal. 0, 1 – 4 |
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Kim, T., He, L., Johnson, M. S., Ding, Y., Long, Q., Moore, J. F., Sharer, J. D., Nagy, T. R., Young, M. E., Wood, P. A., and Yang, Q. (2014) Carnitine Palmitoyltransferase1b deficiency protects mice from diet-induced insulin resistance. J. Diabetes Metab. 5, 361-372 |
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Prasain, J. K., Arabshahi, A., Taub, P. R., Sweeney, S., Moore, R., Sharer, J. D., and Barnes, S. (2013) A validated method for measurement of urinary F2-isoprostanes and prostaglandins by LC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 913-914, 161-168 |
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Reardon, R. R. and Sharer, J. D. (2012) Teaching mitochondrial genetics and disease: a GENA Project curriculum intervention. The American Biology Teacher 74, 224-230 |
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Sharer, J.D. (2009) Mechanisms of toxicity in fatty acid oxidation disorders. pp. 317 – 348. In Endogenous Toxins: Targets for Disease Treatment and Prevention (P. O’Brien and R. Bruce, eds). Wiley-VCH, Weinheim
Ji S, You Y, Kerner J, Hoppel CL, Schoeb TR, Chick WSH, Hamm DA, Sharer JD, Wood PA. (2007) Homozygous carnitine palmitoyltransferase 1b (muscle isoform) deficiency is lethal in the mouse. Mol Genet Metab 93, 314-322
Buhimschi, C. S., Buhimschi, I. A., Yu, C., Wang, H., Sharer, J. D., Diamond, M. P., Petkova, A. P., Garfield, R. E., Saade, G. R., and Wiener, C. P. (2006) The effect of dystocia and previous cesarean uterine scar tissue on the tensile properties of the lower uterine segment. Am J Obstet Gynecol 194, 873-883
Bowzard JB, Sharer JD, Kahn RA. (2005) Assays used in the analysis of Arl2 and its binding partners. Methods Enzymol. 404:453-67.
Sharer JD. (2005) The adenine nucleotide translocase type 1 (ANT1): a new factor in mitochondrial disease. IUBMB Life. 57(9):607-14.
Sharer, J. D. (2005) An Overview of Biochemical Genetics. In Current Protocols in Human Genetics, Unit 17.1 (N. C. Dracopoli, J. L. Haines, B. R. Korf, C. C. Morton, C. E. Seidman, J.G. Seidman, and D. R. Smith, eds.) John Wiley & Sons, Inc.
Tolwani RJ, Hamm DA, Tian L, Sharer JD, Vockley J, Rinaldo P, Matern D, Schoeb TR, Wood PA. (2005) Medium-Chain Acyl-CoA Dehydrogenase Deficiency in Gene-Targeted Mice. PLoS Genet. 1: 205-212
Shern, J. F., Sharer, J. D., Pallas, D. C., Bartolini, F., Cowan, N. J., Reed, M. S., Pohl, J., and Kahn, R. A. (2003) Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A. J Biol Chem. 278: 40829-36.
Sharer, J. D., Shern, J., Van Valkenberg, H., Wallace, D., and Kahn, R. A. (2002) ARL2 and BART enter mitochondria and bind the Adenine Nucleotide Transporter. Mol. Biol. Cell 13, 71-83
Van Valkenburgh, H., Shern, J. F., Sharer, J. D., Zhu, X., and Kahn, R. A. (2001) ADP-ribosylation factors (Arfs) and Arf-like 1 (Arl1) have both specific and shared effectors: characterizing Arl1 binding proteins. J. Biol. Chem. 276, 22826-22837
Sharer, J. D., Koosha, H., Church, W. B., and March, P. E. (1999) The function of conserved amino acid residues adjacent to the effector domain in Elongation Factor G. Proteins: Structure, Function, and Genetics 37, 293-302
Sharer, J. D. and Kahn, R. A. (1999) The Arf-like 2 (ARL2) binding protein, BART: purification, cloning, and initial characterization. J. Biol. Chem. 274, 27553-27561
Pillutla, R. C., Sharer, J. D., Gulati, P. S., Wu, E., Yamashita, Y., Lerner, C. G., Inouye, M., and March, P. E. (1995) Cross-species complementation of the indispensable Escherichia coli era gene highlights amino acid regions essential for activity. J. Bacteriol. 177, 2194-2196
Hou, Y., Lin, Y., Sharer, J. D., and March, P. E. (1994). In vivo selection of conditional-lethal mutations in the gene encoding Elongation Factor G in Escherichia coli. J. Bacteriol. 176, 123-129
Lin, Y., Sharer, J. D., and March, P. E. (1994). GTPase-dependent signaling in bacteria: characterization of a membrane binding site for Era in Escherichia coli. J. Bacteriol. 176, 44-49 |
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