Undergraduate |
University of Maryland |
1973 |
1977 |
BS Microbiology |
Graduate |
University of Texas Medical Branch |
1978 |
1983 |
PhD Microbiology |
Fellowship |
University of Wisconsin, Madison |
1983 |
1987 |
Postdoctoral Fellowship, Virology |
|
Appointment Type |
Department |
Division |
Rank |
Center |
Center for AIDS Research |
Center for AIDS Research |
Professor |
Center |
Center for Biophysical Sciences/Engineering |
Center for Biophysical Sciences/Engineering |
Professor |
Center |
Civitan International Research Center |
Civitan International Research Center |
Professor |
Center |
Comp Arthritis, MSK, Bone & Autoimmunity Ctr |
Comp Arthritis, MSK, Bone & Autoimmunity Ctr |
Professor |
Center |
Comprehensive Cancer Center |
Comprehensive Cancer Center |
Professor |
Center |
Ctr for Clinical & Translational Sci |
Ctr for Clinical & Translational Sci |
Professor |
Secondary |
Genetic & Translational Med |
Genetic & Translational Med |
Professor |
Center |
Informatics Institute |
Informatics Institute |
Professor |
Primary |
Microbiology |
Microbiology |
Professor |
|
Biochemistry and Structural Biology |
Cell, Molecular, & Developmental Biology |
Genetics, Genomics and Bioinformatics |
Medical Scientist Training Program |
Microbiology |
|
Publication |
PUBMEDID |
Virus taxonomy: classification and nomenclature of viruses: Ninth Report of the International Committee on Taxonomy of Viruses. (2012) Ed: King, A.M.Q., Adams, M.J., Carstens, E.B. and Lefkowitz, E.J. San Diego: Elsevier. |
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Zou, N., Lin, B.Y., Duan, F., Lee, K.-Y., Jin, G., Guan, R., Yao, G., Lefkowitz, E.J., Broker, T.R., and Chow, L.T.. 2000. The Hinge of the Human Papillomavirus Type 11 E2 Protein Contains Major Determinants for Nuclear Localization and Nuclear Matrix Association. J. Virology, 74:3761-70. |
10729151 |
Chen, L., Puri, R., Lefkowitz, E.J., and Kakar, S.S. 2000. Identification of the Human Pituitary Tumor Transforming Gene (hPTTG) Family: Molecular Structure, Expression, and Chromosomal Location. Gene, 248:41-50. |
10806349 |
Glass, J. I., Lefkowitz, E. J., Glass, J. S., Heiner, C.R., Chen, E.Y., and Cassell, G.H. 2000. The complete genome sequence of the mucosal pathogen Ureaplasma urealyticum. Nature 407:757-762. |
11048724 |
Hoskins,J.A., Alborn,W. Jr., Arnold,J., Blaszczak,L., Burgett,S., DeHoff,B.S., Estrem,S., Fritz,L., Fu,D.-J., Fuller,W., Geringer,C., Gilmour,R., Glass,J.S., Khoja,H., Kraft,A., LaGace,R., LeBlanc,D.J., Lee,L.N., Lefkowitz,E.J., Lu,J., Matsushima,P., McAhren,S., McHenney,M., McLeaster,K., Mundy,C., Nicas,T.I., Norris,F.H., OGara,M., Peery,R., Robertson,G.T., Rockey,P., Sun,P.-M., Winkler,M.E., Yang,Y., Young-Bellido,M., Zhao,G., Zook,C., Baltz,R.H., Jaskunas,S.Richard, Rosteck,P.R. Jr., Skatrud,P.L. and Glass,J.I. 2001. The Genome of the Bacterium Streptococcus pneumoniae strain R6. Journal of Bacteriology. 183:5709-5717. |
11544234 |
Xiaoying Hou, Michal Mrug, Bradley K. Yoder, Elliot J. Lefkowitz, Gabriel Kremmidiotis, Peter DEustachio, David R. Beier, and Lisa M. Guay-Woodford. 2002. Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease. Journal of Clinical Investigation 109:533-540. |
11854326 |
Chen N, Danila MI, Feng Z, Buller RM, Wang C, Han X, Lefkowitz EJ, Upton C. The genomic sequence of ectromelia virus, the causative agent of mousepox. Virology. 2003 Dec 5;317(1):165-86. |
14675635 |
Minion FC, Lefkowitz EJ, Madsen ML, Cleary BJ, Swartzell SM, Mahairas GG. The genome sequence of Mycoplasma hyopneumoniae strain 232, the agent of swine mycoplasmosis. J Bacteriol. 2004 Nov;186(21):7123-33. |
15489423 |
Wang C, Lefkowitz EJ. SS-Wrapper: a package of wrapper applications for similarity searches on Linux clusters. BMC Bioinformatics. 2004 Oct 28;5(1):171 |
15511296 |
Wang C, Lefkowitz EJ. Genomic multiple sequence alignments: refinement using a genetic algorithm. BMC Bioinformatics. 2005 Aug 8;6:200. |
16086841 |
Li G, Chen N, Roper RL, Feng Z, Hunter A, Danila M, Lefkowitz EJ, Buller RM, Upton C. 2005. Complete coding sequences of the rabbitpox virus genome. J Gen Virol. 86:2969-77. |
16227218 |
Lefkowitz EJ, Wang C, Upton C. Poxviruses: past, present and future. Virus Res. 2006 Apr;117(1):105-18. Epub 2006 Feb 24. |
16503070 |
Parveen S, Sullender WM, Fowler K, Lefkowitz EJ, Kapoor SK, Broor S.Genetic variability in the G protein gene of group A and B respiratory syncytial viruses from India. J Clin Microbiol. 2006 Sep;44(9):3055-64. |
16954227 |
Greene JM, Collins F, Lefkowitz EJ, Roos D, Scheuermann RH, Sobral B, Stevens R, White O, Di Francesco V. National Institute of Allergy and Infectious Diseases bioinformatics resource centers: new assets for pathogen informatics. Infect Immun. 2007 Jul;75(7):3212-9. Epub 2007 Apr 9 |
17420237 |
Minkah N, Hwang Y, Perry K, Van Duyne GD, Hendrickson R, Lefkowitz EJ, Hannenhalli S, Bushman FD. Variola virus topoisomerase: DNA cleavage specificity and distribution of sites in Poxvirus genomes. Virology. 2007 Aug 15;365(1):60-9. Epub 2007 Apr 25. |
17462694 |
Moutaftsi M, Bui HH, Peters B, Sidney J, Salek-Ardakani S, Oseroff C, Pasquetto V, Crotty S, Croft M, Lefkowitz EJ, Grey H, Sette A. Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses. J Immunol. 2007 Jun 1;178(11):6814-20. |
17513729 |
Assarsson E, Greenbaum JA, Sundström M, Schaffer L, Hammond JA, Pasquetto V, Oseroff C, Hendrickson RC, Lefkowitz EJ, Tscharke DC, Sidney J, Grey HM, Head SR, Peters B, Sette A. 2008. Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2140-5. |
18245380 |
Rubins KH, Hensley LE, Bell GW, Wang C, Lefkowitz EJ, Brown PO, Relman DA. 2008. Comparative analysis of viral gene expression programs during poxvirus infection: a transcriptional map of the vaccinia and monkeypox genomes. PLoS ONE. 2008 Jul 9;3(7):e2628. |
18612436 |
Odom MR, Curtis Hendrickson R, Lefkowitz EJ (2009). Poxvirus protein evolution: Family wide assessment of possible horizontal gene transfer events. Virus Res. 2009 Sep;144(1-2):233-49. Epub 2009 May 21. |
19464330 |
Pickett BE, Lefkowitz EJ (2009). Recombination in West Nile Virus: Minimal Contribution to Genomic Diversity. Virus Journal. 6:165. |
19821990 |
Pickett, BE, Striker, R. Lefkowitz EJ. (2010) Evidence for Separation of HCV Subtype 1a into Two Distinct Clades. Journal of Viral Hepatitis. June 2010. |
20565573 |
White, Gregory; Pickett, Brett; Lefkowitz, Elliot; Ottendorfer, Christy; Johnson, Amelia; Stark, Lillian; Unnasch, Thomas. (2011) Phylogenetic Analysis of Eastern Equine Encephalitis Virus Isolates from Florida. Am J Trop Med Hyg. 5:709-17. |
21540379 |
Lefkowitz, E.J., A.K. Pattnaik, and L.A. Ball. 1990. Complementation of a vesicular stomatitis virus glycoprotein G mutant with wild-type protein expressed from either a bovine papilloma virus or a vaccinia virus vector system. Virology 178, 373-383. |
2171187 |
Banerjee S, Sullender WM, Choudekar A, John C, Tyagi V, Fowler K, Lefkowitz EJ, Broor S. (2011) Detection and genetic diversity of human metapneumovirus in hospitalized children with acute respiratory infections in India. J Med Virol. 83:1799-1810. |
21837798 |
Schmidt DJ, Pickett BE, Camacho D, Comach G, Xhaja K, Lennon NJ, Rizzolo K, de Bosch N, Becerra A, Nogueira ML, Mondini A, da Silva EV, Vasconcelos PF, Muñoz-Jordán JL, Santiago GA, Ocazionez R, Gehrke L, Lefkowitz EJ, Birren BW, Henn MR, Bosch I. (2011) A phylogenetic analysis using full-length viral genomes of South American dengue serotype 3 in consecutive Venezuelan outbreaks reveals novel NS5 mutation. Infect Genet Evol. |
21964598 |
J. Rodney Brister, Yiming Bao, Carla Kuiken, Philippe Le Mercier, Elliot Lefkowitz, Raphael Leplae, Ramana Madupu, Ruchi Newman, Richard Scheuermann, Donald Seto, Susmita Shrivastava, Qiandong Zeng, William Klimke and Tatiana Tatusova (2010). Editorial: Towards Viral Genome Annotation Standards, Report from the 2010 NCBI Annotation Workshop. Viruses. 2(10):2258-2268. |
21994619 |
Hendrickson R.C., Wang C., Hatcher E.L., Lefkowitz E.J. (2010) Orthopoxvirus Genome Evolution: The Role of Gene Loss. Viruses. 2(9):1933-1967. |
21994715 |
Lazrak A, Fu L, Bali V, Bartoszewski R, Rab A, Havasi V, Keiles S, Kappes J, Kumar R, Lefkowitz E, Sorscher EJ, Matalon S, Collawn JF, Bebok Z. (2013). The silent codon change I507-ATC->ATT contributes to the severity of the ΔF508 CFTR channel dysfunction. FASEB J. 27: 4630-4645. |
23907436 |
Esteban DJ, Upton C, Bartow-McKenney C, Buller RM, Chen NG, Schriewer J, Lefkowitz EJ, Wang C. (2013). Expression of a non-coding RNA in ectromelia virus is required for normal plaque formation. Virus Genes. Sep 28. |
2407804 |
Muzny CA, Sunesara IR, Kumar R, Mena LA, Griswold ME, Martin DH, Lefkowitz EJ, Schwebke JR, and Swiatlo E. (2013). Characterization of the Vaginal Microbiota among Sexual Risk Behavior Groups of Women with Bacterial Vaginosis. PLoS One, Nov 13;8(11):e80254. |
24236175 |
Stoll ML, Kumar R, Morrow C, and Lefkowitz E. (2014): Dysbiosis of the enteric microbiota in pediatric spondyloarthritis. Arthritis Rheumatol. Mar;66 Suppl 11:S228-9. doi: 10.1002/art.38601. |
24677931 |
Adams MJ, Lefkowitz EJ, King AM, Carstens EB. (2014). Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2014). Arch Virol. 2014 Jun 7. |
24906522 |
Kumar R, Eipers P, Little RB, Crowley M, Crossman DK, Lefkowitz EJ, and Morrow CD. (2014). Getting Started with Microbiome Analysis: Sample Acquisition to Bioinformatics. Current Protocols in Human Genetics, Volume 82, Unit 18.8. |
25042718 |
Hatcher EL., Hendrickson RC, and Lefkowitz EJ. (2014). Identification of Nucleotide-Level Changes Impacting Gene Content and Genome Evolution in Orthopoxviruses. J Virology. December vol. 88. 13651-13668. |
25231308 |
Muzny CA, Sunesara IR, Griswold ME, Kumar R, Lefkowitz EJ, Mena LA, Schwebke JR, Martin DH, and Swiatlo E. (2014). Association between BVAB1 and High Nugent Scores among Women with Bacterial Vaginosis. Diagn Microbiol Infect Dis. Sep 16. S0732-8893(14)00370-8. |
25262105 |
Stoll ML, Kumar R, Morrow CD, Lefkowitz EJ, Cui X, Genin A, Cron RQ, Elson CO. (2014). Altered microbiota associated with abnormal humoral immune responses to commensal organisms in enthesitis-related arthritis. Arthritis Research and Therapy. Vol. 16:486. |
25434931 |
Adams MJ, Hendrickson RC, Dempsey DM, and Lefkowitz EJ. (2015). Tracking the changes in virus taxonomy. Arch Virol. Feb 25. |
25708839 |
Hatcher, EL., Wang, C., and Lefkowitz, EJ. (2015) Genome Variability and Gene Content in Chordopoxviruses: Dependence on Microsatellites. Viruses. 7(4), 2126-2146. |
25912716 |
Adams MJ, Lefkowitz EJ, King AM, Bamford DH, Breitbart M, Davison AJ, Ghabrial SA, Gorbalenya AE, Knowles NJ, Krell P, Lavigne R, Prangishvili D, Sanfaçon H, Siddell SG, Simmonds P, Carstens EB. (2015). Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2015). Arch Virol. 160(7): 1837-1850. |
25913692 |
Stripling J, Kumar R, Baddley JW, Nellore A, Dixon P, Howard D, Ptacek T, Lefkowitz EJ, Tallaj JA, Benjamin WH Jr, Morrow CD, Rodriguez JM. Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant. Open Forum Infect Dis. 2015 Jun 3;2(2):ofv078. doi: 10.1093/ofid/ofv078. eCollection 2015 Apr. PubMed PMID: 26180828; PubMed Central PMCID: PMC4498259. |
26180828 |
Xiao L, Ptacek T, Osborne JD, Crabb DM, Simmons WL, Lefkowitz EJ, Waites KB, Atkinson TP, Dybvig K. Comparative genome analysis of Mycoplasma pneumoniae. BMC Genomics. 2015 Aug 16;16:610. doi: 10.1186/s12864-015-1801-0. PubMed PMID: 26275904; PubMed Central PMCID: PMC4537597. |
26275904 |
Ray A, Basu S, Gharaibeh RZ, Cook LC, Kumar R, Lefkowitz EJ, Walker CR, Morrow CD, Franklin CL, Geiger TL, Salzman NH, Fodor A, Dittel BN. Gut Microbial Dysbiosis Due to Helicobacter Drives an Increase in Marginal Zone B Cells in the Absence of IL-10 Signaling in Macrophages. J Immunol. 2015 Oct 1;195(7):3071-85. doi: 10.4049/jimmunol.1500153. Epub 2015 Aug 31. PubMed PMID: 26324769; PubMed Central PMCID: PMC4575870. |
26324769 |
Justice JL, Verhalen B, Kumar R, Lefkowitz EJ, Imperiale MJ, Jiang M. Quantitative Proteomic Analysis of Enriched Nuclear Fractions from BK Polyomavirus-Infected Primary Renal Proximal Tubule Epithelial Cells. J Proteome Res. 2015 Oct 2;14(10):4413-24. doi: 10.1021/acs.jproteome.5b00737. Epub 2015 Sep 23. PubMed PMID: 26354146; PubMed Central PMCID: PMC4727448. |
26354146 |
Subramaniam A, Kumar R, Cliver SP, Zhi D, Szychowski JM, Abramovici A, Biggio JR, Lefkowitz EJ, Morrow C, Edwards RK. Vaginal Microbiota in Pregnancy: Evaluation Based on Vaginal Flora, Birth Outcome, and Race. Am J Perinatol. 2016 Mar;33(4):401-8. doi: 10.1055/s-0035-1565919. Epub 2015 Oct 19. PubMed PMID: 26479170; PubMed Central PMCID: PMC5166555. |
26479170 |
Hakim JA, Koo H, Dennis LN, Kumar R, Ptacek T, Morrow CD, Lefkowitz EJ, Powell ML, Bej AK, Watts SA. An abundance of Epsilonproteobacteria revealed in the gut microbiome of the laboratory cultured sea urchin, Lytechinus variegatus. Front Microbiol. 2015 Oct 13;6:1047. doi: 10.3389/fmicb.2015.01047. eCollection 2015. PubMed PMID: 26528245; PubMed Central PMCID: PMC4602345. |
26528245 |
Edwards RK, Kumar R, Zhi D, Szychowski J, Subramaniam A, Lefkowitz EJ, Morrow C. Gravidas with class III obesity: evaluating the abdominal skin microbiota above and below the panniculus (.). J Matern Fetal Neonatal Med. 2016 Oct;29(20):3312-6. doi: 10.3109/14767058.2015.1124081. Epub 2015 Dec 23. PubMed PMID: 26600277; PubMed Central PMCID: PMC4975423. |
26600277 |
Kumar R, Maynard CL, Eipers P, Goldsmith KT, Ptacek T, Grubbs JA, Dixon P, Howard D, Crossman DK, Crowley MR, Benjamin WH Jr, Lefkowitz EJ, Weaver CT, Rodriguez JM, Morrow CD. Colonization potential to reconstitute a microbe community in patients detected early after fecal microbe transplant for recurrent C. difficile. BMC Microbiol. 2016 Jan 13;16:5. doi: 10.1186/s12866-015-0622-2. PubMed PMID: 26758906; PubMed Central PMCID: PMC4711103. |
26758906 |
Doggett NA, Mukundan H, Lefkowitz EJ, Slezak TR, Chain PS, Morse S, Anderson K, Hodge DR, Pillai S. Culture-Independent Diagnostics for Health Security. Health Secur. 2016 May-Jun;14(3):122-42. doi: 10.1089/hs.2015.0074. Review. PubMed PMID: 27314653. |
27314653 |
Hakim JA, Koo H, Kumar R, Lefkowitz EJ, Morrow CD, Powell ML, Watts SA, Bej AK. The gut microbiome of the sea urchin, Lytechinus variegatus, from its natural habitat demonstrates selective attributes of microbial taxa and predictive metabolic profiles. FEMS Microbiol Ecol. 2016 Sep;92(9). pii: fiw146. doi: 10.1093/femsec/fiw146. Epub 2016 Jul 1. PubMed PMID: 27368709. |
27368709 |
Adams MJ, Lefkowitz EJ, King AM, Harrach B, Harrison RL, Knowles NJ, Kropinski AM, Krupovic M, Kuhn JH, Mushegian AR, Nibert M, Sabanadzovic S, Sanfaçon H, Siddell SG, Simmonds P, Varsani A, Zerbini FM, Gorbalenya AE, Davison AJ. Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2016). Arch Virol. 2016 Oct;161(10):2921-49. doi: 10.1007/s00705-016-2977-6. Epub 2016 Jul 16. PubMed PMID: 27424026. |
27424026 |
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