| Total Records: 73 |
|
Last Name |
First Name |
Research/Clinical Interest Title |
Keywords |
| AGARWAL |
ANUPAM |
Regulation of heme oxygenase gene expression in kidney and vascular injury |
heme oxygenase, acute kidney injury, transplant nephrology, lymphangiogenesis |
| ALLER |
STEPHEN |
Structure and Function of Human Membrane Proteins Research/Clinical |
Membrane proteins, structure-based drug design, x-ray crystallography, biophysics, biochemistry, pharmacology, blood-brain barrier, cystic fibrosis, multi-drug resistance, drug transport, breast cancer |
| ANANTHARAMAIAH |
GATTADAHALLI |
Apolipoproteins, Amphipathic Helices and Atherosclerosis |
|
| BAILEY |
SHANNON |
Molecular mechanisms of chronic alcohol and obesity induced fatty liver disease |
Molecular mechanisms of alcohol and obesity induced liver diseases; Mitochondrial dysfunction in disease; Molecular bioenergetics; Circadian biology; Redox Signaling; Toxicology |
| BARNES |
STEPHEN |
Bile acids, polyphenols and metabolism, and their effects on protein expression and function in chronic disease |
bile acids, isoflavonoids and polyphenols, metabolomics, proteomics, mass spectrometry |
| BELLIS |
SUSAN |
Role of glycosylation in tumor progression and metastasis |
tumorigenesis, metastasis, cancer stem cell, cell invasion, apoptosis, tumor immunology, |
| BHATNAGAR |
SUSHANT |
Identification and characterization of novel factors in insulin secretion in obesity and type 2 diabetes |
Obesity, Type 2 Diabetes, Beta Cell Biology, Insulin Secretion, SNARE Biology, Secreted Proteins, Insulin Granule Trafficking, Tomosyn Proteins, Post-translational Modifications |
| BJORNSTI |
MARY-ANN |
|
DNA topoisomerase I, yeast genetics, cancer chemotherapeutics, TOR signaling, SUMOylation, DNA damage response, drug resistance, siRNA screening, breast cancer |
| BOLISETTY |
SUBHASHINI |
Mechanisms of injury and repair during Acute Kidney Injury |
Ferritin, iron, heme oxygenase, macrophages, inflammation, acute kidney injury, sepsis |
| BRENNER |
MICHAEL |
Molecular Sudies of Astrocytes in Health and Disease |
astrocyte, GFAP, transcription, neurodegeneration, transgenic mice |
| BROUILLETTE |
CHRISTIE |
Protein Structural Cooperativity and Energetics |
calorimetry, protein folding, thermodynamics, drug discovery |
| CHATTOPADHYAY |
DEBASISH |
Structure-Function Analysis of Proteins |
Structural biology, Protein structure function, Malaria, Chagas' disease, Parasitic disease, Small pox, Bacterial pneumoniae |
| CHESNOKOV |
IGOR |
DNA Replication and Cell Cycle in Eukaryotes |
DNA replication, cytokinesis, Origin Recognition Complex |
| CHOW |
LOUISE |
Human papillomavirus DNA replication and pathogenesis |
HPV infections and cancers |
| DEIVANAYAGAM |
CHAMPION |
Adherence Mechanisms of gram positive bacterial surface proteins. |
|
| DOKLAND |
TERJE |
Structural biology of viral assembly and bacterial pathogenicity |
Staphylococcus, pathogenicity, virus, assembly, bacteriophages, electron microscopy, cryo-EM, crystallography, 3D reconstruction |
| ELGAVISH |
GABRIEL |
NMR Studies of Intact Hearts |
|
| FRANK |
STUART |
Growth Hormone Action and GH Receptor Structure and Function |
growth hormone, signaling, prolactin, IGF-1, growth factors |
| GOLDMAN |
FREDERICK |
Creation of patient-specific gene corrected hematopoietic stem cells in inherited bone marrow failure syndromes using inducible pluripotent stem cell technology |
gene therapy, telomerase, hematopoiesis, inducible pluripotent stem cells, oxidative stress, DNA damage response pathways |
| GRAY |
MICHELLE |
Pathogenesis of Huntington's Disease |
Huntington's disease, neurodegeneration, neuroscience, astrocytes |
| GREEN |
TODD |
|
virology, immunology, antibodies, kidney disease, nephropathy, protein structure, crystallography |
| GROSS |
ALECIA |
GPCR trafficking in neurons and rhodopsin-mediated retinal degenerations |
rhodopsin, autosomal dominant retinitis pigmentosa, GPCR trafficking, rab11, nudC, MKS proteins, NPHP proteins, BBS proteins, retinal degeneration, inflammatory response in retina, cilia, protein trafficking |
| HABEGGER |
KIRK |
FGF21 as mediator of the metabolic actions of glucagon & Duodenal nutrient exclusion enhances glucose metabolism via CNS regulation |
|
| HARTMAN |
JOHN |
Experimental models of gene interaction networks that buffer human disease using cell array phenotyping of yeast gene knockout libraries |
yeast genetics, quantitative high throughput cell array phenotyping (Q-HTCP), gene interaction networks, cellular quiescence, aging, cystic fibrosis, chemotherapy response, systems biology, drug discovery, lab automation |
| HASSAN |
QUAMARUL |
Gene Regulation by Non-coding RNA, Chromatin Remodeling and Modifications |
MicroRNA, Epigenetics, Bone, Tooth, Osteoblast Gene Expression, Odontoblast Gene Regulation |
| HIGGINS |
N |
|
|
| HIGGINS |
N |
Genetic and Biochemical Studies of Chromosome Dynamics |
Topoisomerases, Transposition, Site-specific Recombination, Genetics |
| HUNTER |
CHAD |
Transcriptional control of pancreatic beta cell development and adult islet cell function |
Diabetes, Transcription Factor, Coregulators, Gene Regulation, Organogenesis, Pancreas, Chromatin, Developmental Biology, Endocrinology |
| KEDISHVILI |
NATALIA |
Discovery and characterization of novel enzymes that regulate the conversion of vitamin A to bioactive retinoic acid |
vitamin A, retinoic acid, oxidoreductases, development, differentiation |
| KHARLAMPIEVA |
EUGENIA |
|
stimuli-responsive polymers, drug delivery, cell surface engineering, protein assembly at interfaces |
| KIM |
HELEN |
Proteomics of neuroprotective and chemopreventive actions of dietary phytochemicals |
neuroprotection, proteomics, protein modifications, antioxidant dietary supplements, menopause, neurogenesis |
| KLUG |
CHRISTOPHER |
Hematopoietic stem cell biology, acute leukemia, and pancreatic cancer |
|
| KRISHNA |
NEPALLI |
Structural Biology and Biomolecular NMR Spectroscopy |
Proteins, Structural Biology, NMR |
| KRISHNAMURTHY |
PRASANNA |
Molecular mechanisms of cardiovascular diseases & stem cell-mediated regeneration and repair. |
Myocardial infarction, Heart failure, Stem cells, Cardiovascular regeneration and therapeutics, metabolic diseases, wound healing |
| LAPI |
SUZANNE |
Radiopharmaceuticals for Molecular Imaging |
PET, Cyclotron, radioisotopes, |
| LEFKOWITZ |
ELLIOT |
Microbial Genomics and Evolution; Bioinformatics, and Clinical Informatics |
Viruses, Evolution, Genomics, Bioinformatics, Biomedical Informatics |
| LIMDI |
NITA |
Pharmacogenomics research and Implementation Science |
Personalized Medicine, Precision Medicine, Pharmacogenomics, Implemental Science, Pharmacoepidemiology, Pharmacoeconomics, Warfarin , Antiplatelet drugs, Antithrombotic, comparative effectiveness |
| LU |
RUI |
Epigenetic Mechanisms in Cancer Initiation, Maintenance, and Drug Resistance |
Cancer, Leukemia, Epigenetics, Genomics, Chromatin, Gene regulation, Novel therapeutics |
| LUCIUS |
AARON |
|
|
| MOBLEY |
JAMES |
Director, UAB CCC Mass Spectrometry/ Proteomics Shared Facility |
Cancer, Prostate, Pancreatic, Breast, Biomarkers, Mass Spectrometry |
| MUCCIO |
DONALD |
Retinoids for cancer prevention and therapy |
|
| NAHM |
MOON |
Adaptive and Innate Immune Responses to Pneumococci and Pneumonia Vaccines |
pneumococcus, capsule, innate immunity, pathogenesis, vaccines |
| NIEDERWEIS |
MICHAEL |
Novel proteins in the outer membrane of mycobacteria: Functions, structures, role in tuberculosis and applications |
tuberculosis, virulence, antibiotic resistance, membrane, proteins, transport, nanotechnology |
| NOVAK |
JAN |
Pathogenesis and treatments of chronic diseases, infectious diseases, cancer. IgA nephropathy. Mucosal immunology. Biomarkers. |
|
| PATEL |
RAKESH |
Modulation of Inflammation by Reactive Species and N-glycans |
vascular, hemoglobin, red cells, Inflammation, isoflavones, Nitric oxide, nitrite, N-glycan, matrikine |
| PETIT |
CHAD |
Strain Dependent Structure and Function of the Influenza NS1 Protein |
influenza, nmr, ns1, structural biology, virology |
| PITTLER |
STEVEN |
Basic and Translational Studies of Photoreceptor Metabolism and Retinal Degeneration |
retinitis pigmentosa, phosphodiesterase, cGMP-gated cation channel, photoreceptor, phototransduction |
| PLACZEK |
WILLIAM |
Anti-cancer target validation and structure-based drug discovery. |
NMR spectroscopy, cancer, drug discovery, peptide synthesis, structural biology, apoptosis, signaling |
| PREVELIGE |
PETER |
Structural Biology of Viral Assembly and Infection |
|
| RAMANADHAM |
SASANKA |
Role of Lipid Mediators in Signal Transduction |
Islets, signal transduction, iPLA2, bone, protease inhibitors |
| RENFROW |
MATTHEW |
Analysis of Protein Glycosylation in Human Disease by High Resolution Mass Spectrometry |
Fourier transform mass spectrometry (FT-MS), protein glycosylation, IgA O-glycosylation, IgA nephropathy, proteomics, glycoproteomics |
| ROWE |
STEVEN |
Cystic Fibrosis Clinical and Translational Research |
cystic fibrosis, CFTR, nonsense mutations |
| RYAN |
THOMAS |
Stem Cell Therapies in Animal Models of Human Disease |
Sickle cell anemia, thalassemia, embryonic stem cells, hemoglobin, mutagenesis, gene regulation |
| SAAD |
JAMIL |
HIV-Host Interactions and Fas-Mediated Apoptosis |
HIV, NMR, Cancer, Drug design |
| SCHNEIDER |
DAVID |
Control of RNA polymerase I transcription |
cancer, gene expression, RNA processing, ribosomes, transcription, drug development, enzymology |
| SEGREST |
JERE |
Structural Biology of Supramolecular Assemblies (Particularly Lipoproteins and Membranes) |
|
| SONG |
YUHUA |
An integrated multi-scale computational modeling and biological experimental research program to study apoptosis, cell adhesion and biomaterial design |
Computational Biology/Biomechanics, Mechanotransduction, Protein/Biomembrane structure and function, death receptor-mediated apoptosis, Cell adhesion, Biomaterials |
| STRONG |
THERESA |
Identification of Tumor Antigens and Development of Cancer Vaccines |
gene therapy, immunotherapy, vaccine, Phase I clinical trials |
| SUDARSHAN |
SUNIL |
The Metabolic Basic of Kidney Cancer |
tumor metabolism, epigenetics, renal cancer |
| SZTUL |
ELIZABETH |
Membrane Traffic; Protein Degradation |
Cystic fibrosis, membrane traffic, degradation, quality control |
| THOMPSON |
SUNNIE |
Viral host pathogen interactions |
Host pathogen interactions, Mechanisms of viral translation, IRES, Polyomaviruses, Coronaviruses, Enteroviruses, Flaviviruses, Ribosome, Translational mechanisms in Cancer |
| TOWNES |
TIM |
Developmental Regulation of Gene Expression |
|
| TURNBOUGH |
CHARLES |
Structure/Function of the Bacillus anthracis Exosporium; Bacterial Gene Regulation |
anthrax, Bacillus anthracis, exosporium, E. coli, gene regulation. reiterative transcription, transcription start site switching |
| VAN WAARDENBURG |
ROBERT |
Structure-Function analysis of Tyrosyl-DNA phosphodieasterase I; Developing a DNA Repair Enzyme as Therapeutic Target for Anti-Cancer Treatment |
Structure-function analysis, Mechanism of Action of proteins and drugs (chemotherapeutics), Drug Development for novel therapeutic targets, Post-translational modification by Ubiquitin and SUMO (Small Ubiqitin like modifier), Protein interactions |
| VASSYLYEV |
DMITRY |
Structural studies of prokaryotic transcription |
|
| VELU |
SADANANDAN |
|
|
| VOLPICELLI-DALEY |
LAURA |
Cognitive impairments in Parkinson's disease and Lewy body dementias |
Parkinson's disease, Lewy body dementias, synuclein, tau, glucocerebrosidase, cell biology of the neuron, neurodegeneration |
| WALTER |
MARK |
Structure, Biochemistry, and Function of Cytokines involved in Viral pathogenesis and Autoimmunity |
structural biology, immunology, virology, cytokine, signaling, vaccine, protein design, lupus, interferon, IL-10 |
| WENDE |
ADAM |
Glucose-mediated remodeling of cardiac DNA methylation |
Diabetes, Hypertension, Exercise, Mitochondria, Metabolism, Glucose, Epigenetics, Gene expression, transcription, O-GlcNAc, protein modifications, DNA methylation, Histone modification, GLUT4, PDK2, PDK4 |
| WHITE |
CHARLES |
|
|
| YOUNG |
MARTIN |
|
|
| YUSUF |
NABIHA |
Innate immune mechanisms in tumor development |
toll like receptors, type I interferons, immune system, cancer, T-cells |
| ZHAO |
XINYANG |
The roles of protein arginine methyltransferases in abnormal hematopoiesis |
Arginine methylation, epigenetics, leukemia, stem cell, transcription |
