Appointment Type |
Department |
Division |
Rank |
Center |
Vision Science Research Center (Org-Ret) |
Vision Science Research Center (Org-Ret) |
Professor |
Center |
UAB Immunology Institute |
UAB Immunology Institute |
Professor |
Center |
Nutrition Sciences Research |
Nutrition Obesity Res Ctr (NORC) |
Professor |
Center |
Nephrology Research & Training Center |
Nephrology Research & Training Center |
Professor |
Center |
Integrative Center for Aging Research |
Integrative Center for Aging Research |
Professor |
Center |
GL Ctr for Craniofacial, Oral, & Dental Disorders |
GL Ctr for Craniofacial, Oral, & Dental Disorders |
Professor |
Center |
Cystic Fibrosis Research Center |
Cystic Fibrosis Research Center |
Professor |
Center |
Comprehensive Diabetes Center |
Comprehensive Diabetes Center |
Professor |
Center |
Comprehensive Cancer Center |
Comprehensive Cancer Center |
Professor |
Center |
Comp Arthritis, MSK, Bone & Autoimmunity Ctr |
Comp Arthritis, MSK, Bone & Autoimmunity Ctr |
Professor |
Center |
Civitan International Research Center |
Civitan International Research Center |
Professor |
Primary |
Cell, Developmntl, & Integrative Biology |
Cell, Developmntl, & Integrative Biology |
Professor |
Center |
Cell Adhesion & Matrix Research Center |
Cell Adhesion & Matrix Research Center |
Professor |
|
Cell, Molecular, & Developmental Biology |
Cellular and Molecular Biology Program |
Genetics, Genomics and Bioinformatics |
Hughes Med-Grad Fellowship Program |
Integrative Genetics Graduate Program |
Medical Scientist Training Program |
Pathobiology and Molecular Medicine |
|
Publication |
PUBMEDID |
Svetlana V. Masyukova, Marlene E. Winkelbauer, Corey L. Williams, Jay N. Pieczynski, and Bradley K. Yoder Assessing the pathogenic potential of human Nephronophthisis disease-associated NPHP-4 missense mutations in C. elegans. Human Molecular Genetics 20:2942-2954. (2011) |
3131040 |
Anastasia D. Egorova, Padmini P.S.J. Khedoe, Marie-Jose T.H. Goumans, Bradley K Yoder, Surya M. Nauli, Peter ten Dijke, Robert E. Poelmann, and Beerend P. Hierck. Lack of primary cilia primes shear-induced Endothelial-to-Mesenchymal Transition. Circulation Research, 108(9):1093-101 (2011). |
3094764 |
P. Darwin Bell, Wayne Fitzgibbon, Antine Stenbit, Sandra Gilley, Amber Houston, Kelli Sas, May Amria, Gene P. Siegal, John Bissler, Mehmet Bilgen, Peter Cheng-te Chou, Lisa Guay-Woodford, Bradley K. Yoder, Courtney J. Haycraft Ryan Reichert, and Brian Siroky. Interactions between Cilia, Hypertrophic Signaling, and Renal Cystogensis. Journal of American Society for Neprhology, (2011). PMCID: PMC3083306 |
3083306 |
Mandy J. Croyle, Jonathan M. Lehman, Amber K. O’Connor, Sunny Y Wong, Erik B. Malarkey, Daniela Iribarne, William E. Dowdle, Trenton R. Schoeb, Zoe M. Verney, Mohammad Athar Edward J. Michaud, Jeremy F. Reiter, and Bradley K. Yoder. Role of Epidermal Primary Cilia in the Homeostasis of Skin and Hair Follicles. Development. 138(9):1675-85 (2011). |
3074444 |
Corey L. Williams, Chunmei Li, Katarzyna Kida, Peter N. Inglis, Swetha Mohan, Lucie Semenec, Nathan J. Bialas, Rachel Stupay, Nansheng Chen, Oliver E. Blacque*, Bradley K. Yoder*, and Michel R. Leroux*. MKS and NPHP functional modules establish basal body/transition zone-membrane associations and ciliary gate function during ciliogenesis. *Co-corresponding authors. Journal of Cell Biol. 192(6):1023-41. (2011) |
3063147 |
Edward J Michaud and Bradley K Yoder. Soluble levels of cytosolic tubulin coordinate ciliary length control. Molecular Biol. of the Cell. 22(6):806-16, (2011). |
3057705 |
Ohazama A, Haycraft CJ, Seppala M, Blackburn J, Ghafoor S, Cobourne M, Martinelli DC, Fan CM, Peterkova R, Lesot H, Yoder BK, Sharpe PT. Primary cilia regulate Shh activity in the control of molar tooth number. Development. 2009 Mar;136(6):897-903. Epub 2009 Feb 11. |
2727556 |
High-throughput genome editing and phenotyping facilitated by high resolution melting curve analysis. Thomas HR, Percival SM, Yoder BK, Parant JM. PLoS One. 2014 Dec 11;9(12):e114632. doi: 10.1371/journal.pone.0114632. eCollection 2014. Erratum in: PLoS One. 2015;10(2):e0117764. |
25503746 |
Hippocampal and cortical primary cilia are required for aversive memory in mice. Berbari NF, Malarkey EB, Yazdi SM, McNair AD, Kippe JM, Croyle MJ, Kraft TW, Yoder BK. PLoS One. 2014 Sep 3;9(9):e106576. doi: 10.1371/journal.pone.0106576. eCollection 2014. |
25184295 |
Primary cilia enhance kisspeptin receptor signaling on gonadotropin-releasing hormone neurons. Koemeter-Cox AI, Sherwood TW, Green JA, Steiner RA, Berbari NF, Yoder BK, Kauffman AS, Monsma PC, Brown A, Askwith CC, Mykytyn K. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10335-40. doi: 10.1073/pnas.1403286111. Epub 2014 Jun 30. |
24982149 |
Monitoring endosomal trafficking of the g protein-coupled receptor somatostatin receptor 3. Tower-Gilchrist C, Styers ML, Yoder BK, Berbari NF, Sztul E. Methods Enzymol. 2014;534:261-80. doi: 10.1016/B978-0-12-397926-1.00015-9 |
24359959 |
Deletion of airway cilia results in noninflammatory bronchiectasis and hyperreactive airways. Gilley SK, Stenbit AE, Pasek RC, Sas KM, Steele SL, Amria M, Bunni MA, Estell KP, Schwiebert LM, Flume P, Gooz M, Haycraft CJ, Yoder BK, Miller C, Pavlik JA, Turner GA, Sisson JH, Bell PD |
24213915 |
Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice. Berbari NF, Pasek RC, Malarkey EB, Yazdi SM, McNair AD, Lewis WR, Nagy TR, Kesterson RA, Yoder BK. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7796-801. doi: 10.1073/pnas.1210192110. Epub 2013 Apr 18 |
23599282 |
Quantitative peptidomics of Purkinje cell degeneration mice. Berezniuk I, Sironi JJ, Wardman J, Pasek RC, Berbari NF, Yoder BK, Fricker LD. PLoS One. 2013 Apr 8;8(4):e60981. doi: 10.1371/journal.pone.0060981. Print 2013. PMID: 23593366 Free PMC Article |
23593366 |
Proximal tubule proliferation is insufficient to induce rapid cyst formation after cilia disruption. Sharma N, Malarkey EB, Berbari NF, O'Connor AK, Vanden Heuvel GB, Mrug M, Yoder BK. J Am Soc Nephrol. 2013 Feb;24(3):456-64. doi: 10.1681/ASN.2012020154. Epub 2013 Feb 14. |
23411784 |
Mammalian Clusterin associated protein 1 is an evolutionarily conserved protein required for ciliogenesis. Pasek RC, Berbari NF, Lewis WR, Kesterson RA, Yoder BK. Cilia. 2012 Nov 1;1(1):20. doi: 10.1186/2046-2530-1-20. |
23351563 |
Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model. McIntyre JC, Davis EE, Joiner A, Williams CL, Tsai IC, Jenkins PM, McEwen DP, Zhang L, Escobado J, Thomas S, Szymanska K, Johnson CA, Beales PL, Green ED, Mullikin JC; NISC Comparative Sequencing Program, Sabo A, Muzny DM, Gibbs RA, Attié-Bitach T, Yoder BK, Reed RR, Katsanis N, Martens JR. Nat Med. 2012 Sep;18(9):1423-8. |
22941275 |
Kidney injury accelerates cystogenesis via pathways modulated by heme oxygenase and complement. Zhou J, Ouyang X, Schoeb TR, Bolisetty S, Cui X, Mrug S, Yoder BK, Johnson MR, Szalai AJ, Mrug M. J Am Soc Nephrol. 2012 Jul;23(7):1161-71. doi: 10.1681/ASN.2011050442. Epub 2012 Apr 19. |
22518005 |
Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease. Olteanu D, Liu X, Liu W, Roper VC, Sharma N, Yoder BK, Satlin LM, Schwiebert EM, Bevensee MO. Am J Physiol Cell Physiol. 2012 May 15;302(10):C1436-51. doi: 10.1152/ajpcell.00063.2011. Epub 2012 Feb 1. |
22301060 |
Kierszenbaum AL, Rivkin E, Tres LL, Yoder BK, Haycraft CJ, Bornens M, Rios RM. GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail. Dev Dyn. 240(3):723-36, (2011). |
21337470 |
JR Davenport, AJ Watts, VC Roper, MJ Croyle, TV Groen, JM Wyss, TR. Nagy, RA Kesterson3, and BK Yoder. Conditional disruption of intraflagellar transport in adult mice leads to hyperphagia-induced obesity and slow onset cystic kidney disease. Current Biology Sep 18;17(18):1586-94. Epub 2007 |
2084209 |
O'Connor AK, Kesterson RA, Yoder BK. Generating conditional mutants to analyze ciliary functions: the use of cre-lox technology to disrupt cilia in specific organs. Methods Cell Biol. 2009;93:305-30. Epub 2009 Dec 4. |
20409823 |
Kesterson RA, Berbari NF, Pasek RC, Yoder BK. Utilization of conditional alleles to study the role of the primary cilium in obesity. Methods Cell Biol. 2009;94:163-79. Epub 2009 Dec 23. |
20362090 |
Lehman JM, Laag E, Michaud EJ, Yoder BK. An essential role for dermal primary cilia in hair follicle morphogenesis.J Invest Dermatol. 2009 Feb;129(2):438-48. Epub 2008 Nov 6. |
20362090 |
Williams CL, Masyukova SV, Yoder BK. Normal ciliogenesis requires synergy between the cystic kidney disease genes MKS-3 and NPHP-4.J Am Soc Nephrol. 2010 May;21(5):782-93. Epub 2010 Feb 11. |
20150540 |
Schneider L, Cammer M, Lehman J, Nielsen SK, Guerra CF, Veland IR, Stock C, Hoffmann EK, Yoder BK, Schwab A, Satir P, Christensen ST.Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts. Cell Physiol Biochem. 2010;25(2-3):279-92. |
20110689 |
Clement CA, Kristensen SG, Møllgård K, Pazour GJ, Yoder BK, Larsen LA, Christensen ST. The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation. J Cell Sci. 2009 Sep 1;122(Pt 17):3070-82. Epub 2009 Aug 4. |
19654211 |
Clement CA, Kristensen SG, Møllgård K, Pazour GJ, Yoder BK, Larsen LA, Christensen ST. The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation. J Cell Sci. 2009 Sep 1;122(Pt 17):3070-82. Epub 2009 Aug 4. |
19654211 |
Berbari NF, O'Connor AK, Haycraft CJ, Yoder BK.The primary cilium as a complex signaling center, Curr Biol. 2009 Jul 14;19(13):R526-35. |
19602418 |
Veland IR, Awan A, Pedersen LB, Yoder BK, Christensen ST. Primary Cilia and Signaling Pathways in Mammalian Development, Health and Disease. Nephron Physiol. 2009 Mar 10;111(3):p39-p53 |
19276629 |
Ohazama A, Haycraft CJ, Seppala M, Blackburn J, Ghafoor S, Cobourne M, Martinelli DC, Fan CM, Peterkova R, Lesot H, Yoder BK, Sharpe PT. Primary cilia regulate Shh activity in the control of molar tooth number. Development. Mar;136(6):897-903. (2009) |
19211681 |
Sharma N, Berbari NF, Yoder BK. Ciliary dysfunction in developmental abnormalities and diseases. Curr Top Dev Biol.;85:371-427. (2008) |
19147012 |
Sharma N, Berbari NF, Yoder BK. Ciliary dysfunction in developmental abnormalities and diseases. Curr Top Dev Biol. 2008;85:371-427 |
19147012 |
J Lehman, E Laag, MJ Michaud, BK Yoder. An Essential Role for Dermal Primary Cilia in Hair Follicle Morphogenesis. Journal of Investigative Dermatology, Feb;129(2):438-48. (2009) |
18987668 |
SK Nielsen, K Møllgård, CA Clement, IR Veland, A Awan, BK Yoder, I Novak, ST Christensen. Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines. Dev Dyn. 237(8):2039-52. 2008 |
18629868 |
ET Johnson, T Nicola, K Roarty, BK Yoder, CJ Haycraft, R Serra. Role for primary cilia in the regulation of mouse ovarian function. Dev Dyn. Aug;237(8):2053-60. (2008) |
18629867 |
MB Hovater, D Olteanu, EL Hanson, NL Cheng, B Siroky, A Fintha, P Komlosi, W Liu, LM Satlin, PD Bell, BK Yoder, EM Schwiebert. Loss of apical monocilia on collecting duct principal cells impairs ATP secretion across the apical cell surface and ATP-dependent and flow-induced calcium signals. Purinergic Signal. 2008 Jun;4(2):155-70. |
18368523 |
JM Lehman, EJ Michaud, TR Schoeb, Y Aydin-Son, M Miller, BK Yoder. The Oak Ridge Polycystic Kidney mouse: Modeling ciliopathies of mice and men. Developmental Dynamics 237(8):1960-71. 2008 |
18366137 |
CL Williams, ME Winkelbauer, JC Schafer, EJ Michaud, and BK Yoder. Functional Redundancy of the B9 Proteins and Nephrocystins in C. elegans Ciliogenesis. Mol Biol Cell. 2008 |
18337471 |
PV Tran, CJ Haycraft, TY Besschetnova, A Turbe-Doan, RW Stottmann, BJ Herron, AL Chesebro, H Qiu, PJ Scherz, JV Shah, BK Yoder, and DR Beier. THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia. Nat Genet. 2008 |
18327258 |
C Jones, VC Roper, I Foucher, D Qian, B Banizs, C Petit, BK Yoder, and P Chen. Ciliary proteins link basal body polarization to planar cell polarity regulation. Nat Genet. 40(1):69-77. Epub 2007 Dec 9. (2008) |
18066062 |
JR Davenport, AJ Watts, VC Roper, MJ Croyle, TV Groen, JM Wyss, TR. Nagy, RA Kesterson3, and BK Yoder. Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease. Current Biology Sep 18;17(18):1586-94. Epub 2007 Sep 6. (2007) |
17825558 |
VV Chizhikov,, JR Davenport, Q Zhang, EK Shih, OA Cabello, J Fuchs, BK Yoder and KJ Millen. Cilia proteins control cerebellar morphogenesis by promoting granule progenitor pool expansion. Journal of Neuroscience Sep 5;27(36):9780-9.(2007) |
17804638 |
B Song, CJ Haycraft, HS Seo, BK Yoder, and R Serra. Development of the post-natal growth plate requires intraflagellar transport proteins. Dev Biol. May 1;305(1):202-16. [Epub ahead of print] (2007). |
17359961 |
G Ou, M Koga, OE Blacque, T Murayama, Y Ohshima, JC Schafer, C Li, BK Yoder, MR Leroux, and JM Scholey. Sensory Ciliogenesis in Caenorhabditis elegans: Assignment of IFT components into Distinct Modules Based on Transport and Phenotypic Profiles. Mol Biol Cell. Feb 21; [Epub ahead of print] (2007). |
17314406 |
SR McGlashan, CJ Haycraft, CG Jensen, BK Yoder, and CA Poole. Articular cartilage and growth plate defects are associated with chondrocyte cytoskeletal abnormalities in Tg737(orpk) mice lacking the primary cilia protein polaris. Matrix Biology, 26(4):234-46 (2006). |
17289363 |
B Banizs, P Komlosi, MO Bevensee, EM Schwiebert, PD Bell, BK Yoder. Altered intracellular pH regulation and Na+/HCO3- transporter activity in choroid plexus of the cilia defective Tg737orpk mutant mouse. Am J Physiol Cell Physiol. 2006 Dec 20; [Epub ahead of print] (2006) |
17182727 |
Courtney J. Haycraft, Qihong Zhang, Buer Song, Walker S. Jackson, Peter J. Detloff, Rosa Serra, and Bradley K. Yoder. Intraflagellar Transport is Essential for Endochondral Bone Formation. Development, 134(2):307-16 (2007). |
17166921 |
Siroky BJ, Ferguson WB, Fuson AL, Xie Y, Fintha A, Komlosi P, Yoder BK, Schwiebert EM, Guay-Woodford LM, Bell PD. Loss of Primary Cilia Results in Deregulated and Unabated Apical Calcium Entry in ARPKD Collecting Duct Cells. Am J Physiol Renal Physiol. 290:F1320-8 (2006) |
16396941 |
Marlene E. Winkelbauer, Jenny C. Schafer, Courtney J. Haycraft, Peter Swoboda, and Bradley K. Yoder. The C. elegans homologs of Nephrocystin-1 and Nephrocystin-4 are cilia transition zone proteins involved in chemosensory perception. Journal of Cell Science 118(Pt 23):5575-87 (2005) |
16291722 |
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