Course Catalog

 
06-447 PRECISION MEDICINE: PHARMACOGENOMICS AND CLINICAL APPLICATIONS OF CELL AND GENE THERAPY
Department BIOMEDICAL ENGINEERING Campus Birmingham
Course Type(s) Co-enrolled Elective Facility
Course Director Prasanna Krishnamurthy Enrollment Limit 20
Contact Prasanna Krishnamurthy Enrollment Minimum 5
Email prasanak@uab.edu Address
Birmingham, AL
Phone Fax
Weeks
Normally Offered
See Offering Dates
Prerequisites NO PREREQUISITES AVAILABLE. CONTACT DEPARTMENT. 
Specific Clerkship Prerequisites:
Visiting Students
No LCME students accepted.
No osteopathic students accepted.
Course Description Important component of Precision Medicine is the use of an individual's genomic information to offer targeted treatment, tailored to the individual. This course is designed to introduce concepts of genomic tools in personalized medicine and its potential applications in diagnostics and clinical therapy or disease management. Our course aims to provide participants with basic knowledge of genomics, an overview of the clinical applications of genomic medicine and overview of associated ethical and social issues inherent in the field. To enrich the learning experience for students, the course will utilize didactic lectures, Student-led discussions of case studies and insights from faculty experts in specific precision medicine topics. The case study discussions will examine the main pillars of precision medicine: clinical aspects, tools and technology, potential clinical applications and ethical considerations. Students are expected to prepare for in-class discussions each week either by reading assigned papers or watching supplement lecture or seminar videos. These will be provided via email the week before the class. Learning Objectives: By end of this course, students will be knowledgeable in the following areas: 1) Understanding basic concepts in precision medicine and use of an individual's genomic information to offer targeted treatment, tailored to the individual. 2) Understanding of tools/technologies in precision medicine: NGS, iPSC platform, CRISPR-based gene editing. 3) Describe the clinical applications of genomics and precision medicine principles. 4) Learn about the ethical issues associated with application of precision medicine technologies in clinical setting. 5) Case studies related to precision medicine applications in diseases such as cancer, autoimmune disorder, cardiovascular disease etc. Co-enrolled elective courses offer 2 weeks elective credit each; a student may only receive a maximum of 4 weeks elective credit from co-enrolled courses. STUDENTS ARE ALLOWED TO BE ENROLLED IN ONLY ONE CO-ENROLLED COURSE AT A TIME.
Where To Report Volker Hall Room: VH G094U (BME conference room) Thursday - Time 5-7pm.
Requirements See Evaluation Section.
Evaluation Pass/Fail. Grade based on in class participation, case study presentation and discussion.
Notes This course meet on Thursday from 5-7pm.

The professor reserves the right to edit the syllabus or schedule based on student needs or guest speaker availability. Any changes will be announced in class and re-affirmed via email.

Co-enrolled elective courses offer 2 weeks elective credit each; a student may only receive a maximum of 4 weeks elective credit from co-enrolled courses. STUDENTS ARE ALLOWED TO BE ENROLLED IN ONLY ONE CO-ENROLLED COURSE AT A TIME.