Biochemistry and Structural Biology
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Faculty Detail
Name
Campus Address
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Graduate Biomedical Sciences Affiliations
Biochemistry and Structural Biology
Cell, Molecular, & Developmental Biology
Biographical Sketch
Dr. Q Yang obtained his bachelor and master degrees of medicine in China in the 80's and got his MS degree in Pharmacy from the University of Montana in 1992 and his PhD in cardiac physiology from Washington State University in 1996. After 4 years of post-doctoral training in Cincinnati Children's Hospital Research Foundation, he joined the faculty in the Cardiovascular Research Institute of Morehouse School of Medicine in 2000. Dr. Yang moved his lab to UAB in 2008.
Research/Clinical Interest
Title
Molecular and biochemical mechanisms of myocardial energy metabolism
Description
Research in Dr. Yang’s lab focuses on exploring molecular mechanisms underlying the development and progression of heart failure, especially those related to derangement of myocardial energy metabolism in pathological conditions such as hypertension, obesity and diabetes. His lab uses cutting-edge technologies in molecular genetics to generate and study transgenic and knockout mouse models. A variety of techniques in molecular and cellular biology, biochemistry and Pathophysiology are used to assess these preclinical animal models in an effort to identify mechanisms and get insights into novel translatable therapeutic strategies.
Keywords
PPAR, ATP synthase, mitochondria, energy metabolism, fatty acid metabolism, glucose metabolism, heart failure, cardiac hypertrophy, diabetic cardiomyopathy