Total Records: 62 |
Last Name |
First Name |
Research/Clinical Interest Title |
Keywords |
ALLER |
STEPHEN |
Structure and Function of Human Membrane Proteins Research/Clinical |
Membrane proteins, structure-based drug design, x-ray crystallography, biophysics, biochemistry, pharmacology, blood-brain barrier, cystic fibrosis, multi-drug resistance, drug transport, breast cancer |
AMM |
HOPE |
Genetics and Pharmacology of Oral Tumors |
oral cancer, squamous cell carcinoma, HNSCC, genetics, hedgehog siganling, pharmacology |
BALKOVETZ |
DANIEL |
Epithelial Cell Biology; Epithelial Cell Signal Regulation; Regulation of paracellular transport across epithelial cell tight junctions |
epithelial cells, claudins, tight junctions, E-cadherin, hepatocyte growth factor, ERK, MDCK |
BALLINGER |
SCOTT |
Environmental cardiology, free radical biology, mitochondrial function, mitochondrial - nuclear interactions |
mitochondria, oxidative stress, evolutionary medicine, cardiovascular disease, cancer, metabolism |
BELLIS |
SUSAN |
Role of glycosylation in tumor progression and metastasis |
tumorigenesis, metastasis, cancer stem cell, cell invasion, apoptosis, tumor immunology, |
BJORNSTI |
MARY-ANN |
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DNA topoisomerase I, yeast genetics, cancer chemotherapeutics, TOR signaling, SUMOylation, DNA damage response, drug resistance, siRNA screening, breast cancer |
CHANG |
CHENBEI |
Growth Factor Signaling and Transcription Regulation in Vertebrate Development |
TGF-beta, neural induction, BMP, ErbB, gastrulation, cell movement |
CHEN |
YABING |
Gene Regulation and Function in the Pathogenesis of Cardiovascular Disease and Aging |
vascular smooth muscle cells, excellular matrix, vascular calcification, atherosclerosis, diabetes, aging |
DAVIS |
RANDALL |
The developmental immunology of lymphocytes and immunoreceptor biology. Lymphoproliferative disorders and mechanisms that contribute to lymphomagenesis and autoimmunity. |
Immunology, lymphoproliferative disorders, autoimmunity, B cells, Fc receptors, CLL, FCRL |
DING |
QIANG |
Molecular mechanisms of organ fibrosis |
Signal Transduction; Cell Physiology, Adhesion & Migration Signaling; Molecular Genetics & Disease; Gene Regulation and Expression |
ELTOUM |
ISAM-ELDIN |
- Clinical research in diagnostic cytology and surgical pathology- Tumorogenesis of prostate cancer and chemoprevetion - HPV infection |
EUS-FNA, Prostate cancer in transgenic animals, HPV infection, Cytology, Immunopathology |
FALANY |
CHARLES |
Biochemical and physiological properties of human cytosolic sulfotransferases |
|
FENG |
XU |
The RANKL/RANK/OPG System in Health and Disease |
RANKL, RANK, OPG, Cell Differentiation, Cell Signaling, Osteoclast, Mammary Gland, Breast Cancer |
FRANK |
STUART |
Growth Hormone Action and GH Receptor Structure and Function |
growth hormone, signaling, prolactin, IGF-1, growth factors |
FULLER |
CATHERINE |
ENaC/ASIC Ion Channels; |
Sodium channels, glioma, migration, proliferation, cancer, signaling, polycystic kidney disease |
HAN |
XIAOSI |
Epigenetic Regulation in Glioblastoma |
glioblastoma, protein argine methyltransferase-5, glioma stem cell, epigenetics |
HARDY |
ROBERT |
Translational research |
oxidative stress, cancer, insulin resistance |
HARTMAN |
JOHN |
Experimental models of gene interaction networks that buffer human disease using cell array phenotyping of yeast gene knockout libraries |
yeast genetics, quantitative high throughput cell array phenotyping (Q-HTCP), gene interaction networks, cellular quiescence, aging, cystic fibrosis, chemotherapy response, systems biology, drug discovery, lab automation |
HEL |
ZDENEK |
Immunology and pathogenesis of HIV-1 / AIDS; Neutrophil biology; Effect of hormonal contraception on immune system; Design of novel strategies for immunotherapy of cancer; Covid-19. |
Immunology, Neutrophils, HIV-1, Vaccine, Cancer, Covid-19. |
HILDRETH |
BLAKE |
Role of macrophages and osteoclasts in bone metastasis and primary bone tumors |
macrophage, osteoclast, breast cancer, primary bone tumor, bone, metastasis |
HJELMELAND |
ANITA |
Targeting Brain Tumor Initiating Cells and the Tumor Microenvironment |
Brain Tumor, Tumor Microenvironment, Tumor Initiating Cell, Cancer Stem Cell |
HU |
HUI |
Transcriptional Regulation of Adaptive Immunity |
Tfh cell differentiation, GC responses, CD8+ T cell quiescence/activation, T cell responses, immune memory, vaccines |
JAVED |
AMJAD |
Genetic and Molecular Signaling for Cellular Differentiation and Skeletogenesis |
Osteoblast, Bone Development, Gene Regulation, Osteoporosis |
KARTHIKEYAN |
MYTHREYE |
Molecular and cellular mechanisms of signaling during metastasis |
ovarian cancer, TGFbeta, BMP, inhibin/activin, betaglycan, cellular signaling, extracellular matrix , cell survival mechanisms |
KING |
PETER |
1) RNA Regulation of Inflammation in ALS and other Neurodegenerative Disorders, 2) Smads as Biomarkers of ALS Disease Progressionh |
RNA stability; AU-rich elements; cytokines and chemokines; glioblastoma; amyotrophic lateral sclerosis, stroke, spinal cord injury, HuR, KSRP |
KLUG |
CHRISTOPHER |
Hematopoietic stem cell biology, acute leukemia, and pancreatic cancer |
|
KRISHNA |
NEPALLI |
Structural Biology and Biomolecular NMR Spectroscopy |
Proteins, Structural Biology, NMR |
LAHTI |
ADRIENNE |
Neuroimaging |
psychiatry, schizophrenia, research, lahti |
LARIMER |
BENJAMIN |
Development of Novel Biological Agents to Personalize Cancer Therapy |
Immunotherapy, Phage Display, Nanobodies, Molecular Imaging |
LEAVENWORTH |
JIANMEI |
Cancer-Immune cell Crosstalk: Discovery of new targets for cancer immunotherapy |
Immunology, Cancer Immunology, Immunotherapy, Treg, NK cells, glioma |
LIN |
DIANA |
|
head and neck pathology, cytopathology, endocrine pathology, pulmonary pathology, dermatopathology |
LIU |
RUNHUA |
Cancer Cell Biology and Cancer Genetics |
|
LU |
RUI |
Epigenetic Mechanisms in Cancer Initiation, Maintenance, and Drug Resistance |
Cancer, Leukemia, Epigenetics, Genomics, Chromatin, Gene regulation, Novel therapeutics |
MANNE |
UPENDER |
Translational research in grastrointestinal malignancies and breast cancer |
Colorectal Cancer, GI malignancies, Breast Cancer, Molecular Biomarkers, Racial/Ethnic Disparities, Cancer Control & Prevention |
MARKERT |
JAMES |
Engineering Herpes Simplex Viruses for the Therapy of Cancer |
glioma, gene therapy, brain tumors, herpes simplex, cancer therapy, immunotherapy, anti-angiogenic therapy |
MITRA |
KASTURI |
Exploring the significance of mitochondrial structural change in health and disease |
Mitochondria, Cell proliferation, Energetics, Cancer, Stem cells |
MURPHY-ULLRICH |
JOANNE |
Extracellular Matrix Control of Cell and Growth Factor Function, multiple myeloma, diabetic complications, glaucoma |
atherosclerosis, diabetic complications, tumor microenvironment, multiple myeloma, osteolytic bone disease, glaucoma, fibrosis, TGF-beta, thrombospondin |
NORIAN |
LYSE |
Understanding the effects of diet and obesity on anti-tumor immunity |
cancer immunology, immunotherapy, obesity, diet, kidney cancer, breast cancer |
PARANT |
JOHN |
Animal Models of Genomic Instability, p53 Regulation, Cancer and Mitotic Dysfunction |
Zebrafish, Mouse, Li Fraumeni Syndrome, Roberts syndrome, Birth Defects, Tumor Suppressor, Genomic Instability, Aneuploidy, Mitosis, DNA damage, Cancer, and Apoptosis. |
PATEL |
RAKESH |
Modulation of Inflammation by Reactive Species and N-glycans |
vascular, hemoglobin, red cells, Inflammation, isoflavones, Nitric oxide, nitrite, N-glycan, matrikine |
PLACZEK |
WILLIAM |
Anti-cancer target validation and structure-based drug discovery. |
NMR spectroscopy, cancer, drug discovery, peptide synthesis, structural biology, apoptosis, signaling |
PONNAZHAGAN |
SELVARANGAN |
Experimental Cancer Therapeutics and BOne Diseases: From Basic to Preclinical Studies |
Breast Cancer; Prostate Cancer; Osteoimmunology; Bone Metastasis; Osteogenesis; Bone Fracture; Stem Cell Therapy |
REN |
BIN |
Epigenetic and Transcriptional Regulation of Functional Angiogenesis and Arteriogenesis in Cancer, Heart and Vascular Diseases, Alzheimer's Disease and Diabetes. |
Endothelial cells, Angiogenesis, Arteriogenesis, Molecular and cellular biology, Cancer, Ischemic heart and vascular diseases, Diabetes, Alzherimer's disease |
RENFROW |
MATTHEW |
Analysis of Protein Glycosylation in Human Disease by High Resolution Mass Spectrometry |
Fourier transform mass spectrometry (FT-MS), protein glycosylation, IgA O-glycosylation, IgA nephropathy, proteomics, glycoproteomics |
SAMANT |
RAJEEV |
Tumor progression and metastasis of cancer. |
Ribosome Biogenesis, Epithelial-Mesenchymal-Transition, mylti-protein complexes, transcription regulation, nucleolus, protein stability, chaperones, Hest shock proteins |
SANDERSON |
RALPH |
Molecular Regulation of the Tumor Microenvironment |
tumor, microenvironment, cancer, heparan sulfate, proteoglycan, heparanase, exosomes, metastasis, bone, myeloma, breast cancer, drug resistance |
SHEVDE-SAMANT |
LALITA |
Investigating molecular signaling mechanisms that present as fundamental aberrations in tumor cells or their immune microenvironment |
Tumor progression, metastasis, innate and adaptive immune microenvironment, signaling, cancer stem cells, chemoresistance, metabolism, osteolysis, Merlin, Hedgehog pathway, Wnt pathway |
SHRESTHA |
SADEEP |
|
|
SIEGAL |
GENE |
Gene therapy of solid tumors, cancer biology, tumors of bone |
Bone Tumors, Cancer Gene Therapy, Invasion and Metastasis |
SINGH |
KESHAV |
Mitochondrial Metabolism, Mitochondria-to-Nucleus Retrograde Cross Talk, Oxidative Stress, Genomic Instability and Its Role in Tumor Progression and Metastasis |
mitochondria, genomic instability, cancer, breast cancer, prostate, arsenic, oxidative stress, metabolism, tumor progression, tumor metastasis |
SONG |
YUHUA |
An integrated multi-scale computational modeling and biological experimental research program to study apoptosis, cell adhesion and biomaterial design |
Computational Biology/Biomechanics, Mechanotransduction, Protein/Biomembrane structure and function, death receptor-mediated apoptosis, Cell adhesion, Biomaterials |
STRONG |
THERESA |
Identification of Tumor Antigens and Development of Cancer Vaccines |
gene therapy, immunotherapy, vaccine, Phase I clinical trials |
TANG |
JIANMING |
Genetic and Epigenetic Correlates of Infection and Immunity |
Immunogenetics, Infectious Disease, Pharmacogenetics, Public Health |
TOLLEFSBOL |
TRYGVE |
|
|
VAN WAARDENBURG |
ROBERT |
Structure-Function analysis of Tyrosyl-DNA phosphodieasterase I; Developing a DNA Repair Enzyme as Therapeutic Target for Anti-Cancer Treatment |
Structure-function analysis, Mechanism of Action of proteins and drugs (chemotherapeutics), Drug Development for novel therapeutic targets, Post-translational modification by Ubiquitin and SUMO (Small Ubiqitin like modifier), Protein interactions |
VARAMBALLY |
SOORYANARAYANA |
Cancer molecular genetics, Cancer Biomarker Discovery, Cancer Biology and Therapeutic Targeting |
UALCAN, TCGA, CPTAC, Genomics, Bioinformatics, Proteomics, Biomarker, Integrative Cancer Biology and Therapeutics. |
WELNER |
ROBERT |
Studying the bone marrow microenvironment during steady-state, inflammation, or leukemia |
stem cell, hematopoiesis, niche, stromal cells, immune response, leukemia |
XU |
HUI |
The role of IL-17 in inflammation associated tumor development |
T cells, dendritic cells, cytokines, tumor suppressor |
XU |
JIA |
Investigating the mechanisms by which oncogenic signaling pathways impact tumor cell division, growth and metastasis |
AURKB, PI3K/AKT/PTEN pathway, Mitosis, Cancer Biology, Cancer signaling pathway, PROTAC, AAV gene therapy |
YANG |
EDDY |
Targeting DNA repair pathways to augment the therapeutic ratio for cancer patients |
nanostring, profiling, DNA damage, DNA repair, EGFR, cancer, PARP, apoptosis, brain, protection, GSK3 |
YUSUF |
NABIHA |
Innate immune mechanisms in tumor development |
toll like receptors, type I interferons, immune system, cancer, T-cells |
ZAYZAFOON |
MAJD |
The Role of Calcium Signaling in the pathogenesis of disease |
Osteoblasts, Bone, Prostate Cancer, Osteosarcoma, Calmodulin Kinase, NFAT, AP-1, Bone metastasis, HDAC, histone acetylation, DNA methyltransferase |
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