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Faculty Detail    
Name SHUKO HARADA
  
Campus Address NP 3540 Zip 6823
Phone  (205) 996-5848
E-mail  sharada@uabmc.edu
Other websites
     

Education
Medical School  University of Tokyo Faculty of Medicine, Tokyo, Japan    1985  M.D. 

Certifications
American Board of Pathology, Anatomic and Clinical  2008 
Molecular Genetic Pathology  2011 


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Genomic Diagnostics & Bioinformatics  Genomic Diagnostics & Bioinformatics Professor
Center  Comprehensive Cancer Center  Comprehensive Cancer Center Professor

Biographical Sketch 
Dr. Harada received her medical degree from the University of Tokyo Faculty of Medicine and completed her residency training for Internal Medicine, worked as an internist in Endocrinology and Metabolism in Tokyo, Japan. She moved to USA and conducted research on insulin signal transduction and gene regulation at University of Pennsylvania, a part of which as a research faculty. She completed her residency at Drexel University College of Medicine followed by surgical pathology and molecular genetic pathology fellowship at University of Pennsylvania and Johns Hopkins University, respectively. She joined the faculty at UAB in August, 2011. Dr. Harada is board certified in Anatomic and Clinical Pathology as well as Molecular Genetic Pathology. Currently she is Head of Molecular Diagnostic Laboratory, which offers wide variety of molecular and genomic testing for infectious diseases and oncology including next generation sequencing analysis. She has particular interests in precision medicine in oncology and pharmacogenomics, and a member of Precision Medicine Institute and Comprehensive Cancer Center.

Society Memberships
Organization Name Position Held Org Link
AMP (Association for Molecular Pathology)  member   
Association of Clinical Scientists (ACS)  fellow member   
College of American Pathologists   fellow member   
United States and Canadian Academy of Pathology  member   
 



Research/Clinical Interest
Title
Molecular Profiling of Breast ductal carcinoma in situ; Implementation of next generation sequencing into precision medicine
Description
My research interests are following; 1. Clinical implementation of next generation sequencing of cancer and correlation with clinical status 2. Molecular profiling and discovery of molecular markers in ductal carcinoma in-situ of breast 3. Implementation of genotype guided decision making into clinical workflow

Selected Publications 
Publication PUBMEDID
Harada S, Smith RM, Smith JA, White MF, Jarett L. Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc and mitogen activated protein kinase, but not insulin receptor substrate-1 and phosphatidyl inositol 3-kinase activation. J Biol Chem. 271: 30222-30226, 1996.  8939974 
Smith RM, Harada S, Jarett L. Roles of insulin internalization and other signaling pathways in the pleiotropic effects of insulin. Intern Rec Cytol. 173: 243-280, 1997  9127955 
Smith RM, Harada S, Smith JA, Zhang S, Jarett L. Insulin-induced protein tyrosine phosphorylation cascade and signaling molecules are enriched in membrane caveolae in hepatoma cells. Cellular Signalling 10: 355-362, 1998  9692679 
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Keywords
molecular pathology, breast pathology, precision medicine