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Faculty Detail    
Name FARAH D LUBIN
Associate Professor		  
Campus Address SHEL 1102 Zip 2182
Phone  (205) 996-6084
E-mail  flubin@uab.edu
Other websites www.lubinlab.com
     


Faculty Appointment(s)
Appointment Type Department Division Rank
Primary  Neurobiology  Neurobiology Professor
Secondary  Cell, Developmntl, & Integrative Biology  Cell, Developmntl, & Integrative Biology Associate Professor
Center  Alzheimer's Disease Center  Alzheimer's Disease Center Professor
Center  Civitan International Research Center  Civitan International Research Center Professor
Center  Comprehensive Neuroscience Center  Comprehensive Neuroscience Center Professor
Center  Ctr for Clinical & Translational Sci  Ctr for Clinical & Translational Sci Professor
Center  Ctr for Glial Bio in Med  Ctr for Glial Bio in Med Professor
Center  Ctr Neurodegeneration & Exp Ther (CNET)  Ctr Neurodegeneration & Exp Ther (CNET) Professor
Center  Epilepsy Center  Epilepsy Center Professor
Center  Evelyn F. McKnight Brain Institute  Evelyn F. McKnight Brain Institute Professor
Center  GL Ctr for Craniofacial, Oral, & Dental Disorders  GL Ctr for Craniofacial, Oral, & Dental Disorders Professor
Center  Integrative Center for Aging Research  Integrative Center for Aging Research Professor

Graduate Biomedical Sciences Affiliations
Cell, Molecular, & Developmental Biology 
Cellular and Molecular Biology Program 
Genetics, Genomics and Bioinformatics 
Neuroscience 

Biographical Sketch 
www.lubinlab.com Dr. Lubin received her undergraduate degree Summa Cum Laude from Alabama State University in Montgomery, Alabama and her Ph.D. in Cell/Molecular Biology and Immunology from Binghamton University in Binghamton, New York. She has also worked as a research assistant at Memorial Sloan Kettering Cancer Center in New York. Dr. Lubin has completed two postdoctoral fellowships in Molecular Neuroscience at Baylor College of Medicine in Houston, Texas and most recently in the Department of Neurobiology at UAB. Dr. Lubin is a recipient of a Pathway to Independence Award from the National Institutes of Health (NIH/NIMH) and FASEB Award. Her research gives insight not only into the cellular and molecular mechanisms underlying long-term memory in the healthy brain, but also insights into the fundamental mechanisms that might be deranged in cognitive disorders. Dr. Lubin’s research is primarily directed towards characterizing the role of epigenetic mechanisms and signaling cascades that mediate the interaction of transcription factors like NFkappaB to chromatin, and determining how they participate in the regulation of gene expression as they relate to learning and memory.



Research/Clinical Interest
Title
Molecular genetic mechanisms in learning and memory
Description
Dr. Lubin’s research interest is focused on understanding the cellular and molecular mechanisms underlying transcriptional regulation of genes in the nervous system to mediate cognition and how these mechanisms are altered with aging and cognitive disorders including epilepsy and Alzheimer’s disease. Currently, our research is directed at characterizing the role of epigenetic mechanisms, such as histone modifications, DNA methylation, and the interaction of the NF-kB signaling pathway with chromatin to determine how these molecular changes participate in the regulation of gene expression related to the normal process of learning and memory and how they are deranged with cognitive deficits.

Keywords
Epigenetics, signal transduction, gene transcription, CRISPR-dCas9, neurology, neuroscience, learning and memory, aging, epilepsy, Alzheimer's Disease