Undergraduate |
Fudan University, Shanghai, China |
|
1987 |
Bachelor of Science |
Graduate |
University of Vermont, Burlington, VT |
|
1994 |
Ph.D. in Zoology/Molecular Biology |
Fellowship |
Washington University School of Medicine, St. Louis, MO |
|
1999 |
Bone Biology |
|
Appointment Type |
Department |
Division |
Rank |
Center |
UAB Immunology Institute |
UAB Immunology Institute |
Professor |
Center |
Comp Arthritis, MSK, Bone & Autoimmunity Ctr |
Comp Arthritis, MSK, Bone & Autoimmunity Ctr |
Professor |
Center |
Comprehensive Cancer Center |
Comprehensive Cancer Center |
Professor |
Center |
Integrative Center for Aging Research |
Integrative Center for Aging Research |
Professor |
Center |
Ctr for Clinical & Translational Sci |
Ctr for Clinical & Translational Sci |
Professor |
Center |
Center for Biophysical Sciences/Engineering |
Center for Biophysical Sciences/Engineering |
Professor |
Center |
Cell Adhesion & Matrix Research Center |
Cell Adhesion & Matrix Research Center |
Professor |
Center |
Biomatrix Eng Regen Med (BERM) Ctr |
Biomatrix Eng Regen Med (BERM) Ctr |
Professor |
Primary |
Joint Pathology |
Molecular & Cellular Pathology |
Professor |
|
Cancer Biology |
Immunology |
Medical Scientist Training Program |
Molecular and Cellular Pathology Program |
Pathobiology and Molecular Medicine |
|
Publication |
PUBMEDID |
Feng X (2005) Regulatory roles and molecular signaling of TNF family members in osteoclasts. Gene. 350(1):1-13. Review. |
15777737 |
Shi Z, Silveira A, Patel P, Feng X (2004) YY1 is involved in RANKL-induced transcription of the tartrate-resistant acid phosphatase gene in osteoclast differentiation. Gene. 343(1):117-26. |
15563837 |
Shi Z, Silveira A, Patel P, Feng X (2004) YY1 is involved in RANKL-induced transcription of the tartrate-resistant acid phosphatase gene in osteoclast differentiation. Gene. 343(1):117-26. |
15563837 |
Liu W, Xu D, Yang H, Xu H, Shi Z, Cao X, Takeshita S, Liu J, Teale M, Feng X (2004) Functional identification of three receptor activator of NF-kappa B cytoplasmic motifs mediating osteoclast differentiation and function. J Biol Chem. 279(52):54759-69. |
15485878 |
Xu D, Shi Z, McDonald J, Pan G, Cao X, Yu X, Feng X (2004) Development of a chimaeric receptor approach to study signalling by tumour necrosis factor receptor family members. Biochem J. 383(Pt 2):219-25. |
15250821 |
Pan G, Wu X, McKenna MA, Feng X, Nagy TR, McDonald JM (2004) AZT enhances osteoclastogenesis and bone loss. AIDS Res Hum Retroviruses. 20(6):608-20. |
15242537 |
Wang S, Skorczewski J, Feng X, Mei L, Murphy-Ullrich JE (2004) Glucose up-regulates thrombospondin 1 gene transcription and transforming growth factor-beta activity through antagonism of cGMP-dependent protein kinase repression via upstream stimulatory factor 2. J Biol Chem. 279(33):34311-22. |
15184388 |
Wu X, McKenna MA, Feng X, Nagy TR, McDonald JM (2003) Osteoclast apoptosis: the role of Fas in vivo and in vitro. Endocrinology. 144(12):5545-55. |
12960091 |
Zhang L, Feng X, McDonald JM (2003) The role of calmodulin in the regulation of osteoclastogenesis. Endocrinology. 144(10):4536-43. |
12960067 |
Xiong WC, Feng X (2003) PYK2 and FAK in osteoclasts. Front Biosci. 8:d1219-26. |
12957821 |
Liu Y, Shi Z, Silveira A, Liu J, Sawadogo M, Yang H, Feng X (2003) Involvement of upstream stimulatory factors 1 and 2 in RANKL-induced transcription of tartrate-resistant acid phosphatase gene during osteoclast differentiation. J Biol Chem. 278(23):20603-11. |
12663664 |
Wang Q, Xie Y, Du QS, Wu XJ, Feng X, Mei L, McDonald JM, Xiong WC (2003) Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin. J Cell Biol. 160(4):565-75. |
12578912 |
Kintscher U, Lyon C, Wakino S, Bruemmer D, Feng X, Goetze S, Graf K, Moustakas A, Staels B, Fleck E, Hsueh WA, Law RE (2002) PPARalpha inhibits TGF-beta-induced beta5 integrin transcription in vascular smooth muscle cells by interacting with Smad4. Circ Res. 91(11):e35-44. |
12456495 |
Feng X, Takeshita S, Namba N, Wei S, Teitelbaum SL, Ross FP (2002) Tyrosines 559 and 807 in the cytoplasmic tail of the macrophage colony-stimulating factor receptor play distinct roles in osteoclast differentiation and function. Endocrinology. 143(12):4868-74. |
12446614 |
Gupta A, Tenenhouse HS, Hoag HM, Wang D, Khadeer MA, Namba N, Feng X, Hruska KA (2001) Identification of the type II Na(+)-Pi cotransporter (Npt2) in the osteoclast and the skeletal phenotype of Npt2-/- mice. Bone. 29(5):467-76. |
11704500 |
Feng X, Novack DV, Faccio R, Ory DS, Aya K, Boyer MI, McHugh KP, Ross FP, Teitelbaum SL (2001) A Glanzmann's mutation in beta 3 integrin specifically impairs osteoclast function. J Clin Invest. 107(9):1137-44. |
11342577 |
Wan M, Shi X, Feng X, Cao X (2001) Transcriptional mechanisms of bone morphogenetic protein-induced osteoprotegrin gene expression. J Biol Chem. 276(13):10119-25. Epub 2001 Jan 3. |
11139569 |
Lai CF, Feng X, Nishimura R, Teitelbaum SL, Avioli LV, Ross FP, Cheng SL (2000) Transforming growth factor-beta up-regulates the beta 5 integrin subunit expression via Sp1 and Smad signaling. J Biol Chem. 275(46):36400-6. |
10964912 |
Cheng SL, Lai CF, Fausto A, Chellaiah M, Feng X, McHugh KP, Teitelbaum SL, Civitelli R, Hruska KA, Ross FP, Avioli LV (2000) Regulation of alphaVbeta3 and alphaVbeta5 integrins by dexamethasone in normal human osteoblastic cells. J Cell Biochem. 77(2):265-76. |
10723092 |
Feng X, Teitelbaum SL, Quiroz ME, Cheng SL, Lai CF, Avioli LV, Ross FP (2000) Sp1/Sp3 and PU.1 differentially regulate beta(5) integrin gene expression in macrophages and osteoblasts. J Biol Chem. 275(12):8331-40. |
10722663 |
McHugh KP, Hodivala-Dilke K, Zheng MH, Namba N, Lam J, Novack D, Feng X, Ross FP, Hynes RO, Teitelbaum SL (2000) Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts. J Clin Invest. 105(4):433-40. |
10683372 |
Feng X, Teitelbaum SL, Quiroz ME, Towler DA, Ross FP (1999) Cloning of the murine beta5 integrin subunit promoter. Identification of a novel sequence mediating granulocyte-macrophage colony-stimulating factor-dependent repression of beta5 integrin gene transcription. J Biol Chem. 274(3):1366-74. |
9880508 |
Feng X, Happ GM (1996) Isolation and sequencing of the gene encoding Sp23, a structural protein of spermatophore of the mealworm beetle, Tenebrio molitor. Gene. 179(2):257-62. |
8972909 |
Cao X, Teitelbaum SL, Zhu HJ, Zhang L, Feng X, Ross FP (1996) Competition for a unique response element mediates retinoic acid inhibition of vitamin D3-stimulated transcription. J Biol Chem. 271(34):20650-4. |
8702813 |
Paesen GC, Feng X, Happ GM (1996) Structure of a D-protein gene and amino-acid sequences of the highly repetitive D-proteins secreted by the accessory glands of the mealworm beetle. Biochim Biophys Acta. 1293(2):171-6. |
8620026 |
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