Appointment Type |
Department |
Division |
Rank |
Primary |
Clinical Pathology |
Anatomic Pathology |
Professor |
Center |
Comprehensive Cancer Center |
Comprehensive Cancer Center |
Professor |
Center |
Minority Health & Research Center |
Minority Health & Research Center |
Professor |
Center |
Nutrition Sciences Research |
Nutrition Obesity Res Ctr (NORC) |
Professor |
Secondary |
Surgery - General Surgery |
Surgery - Gen Surg Gastrointestinal Section |
Professor |
|
Cancer Biology |
Integrative Biomedical Sciences |
Medical Scientist Training Program |
Molecular and Cellular Pathology Program |
Pathobiology and Molecular Medicine |
|
Publication |
PUBMEDID |
Vu T, Datta A, Banister C, Jin L, Yuan G, Samuel T, Bae S, Eltoum IE, Manne U, Zhang B, Welner RS, Mitra K, Buckhaults P, Datta PK. STRAP is a Critical Mediator of APC Mutation-Induced Intestinal Tumorigenesis through a Feed-Forward Mechanism. Gastroenterology. 2021 Sep 11:S0016-5085(21)03489-2. doi: 10.1053/j.gastro.2021.09.010. |
34520730 |
Saleh M, Chandrashekar DS, Shahin S, Agarwal S, Kim HG, Behring M, Shaikh AJ, Moloo Z, Eltoum IA, Yates C, Varambally S, Manne U. Comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian Women.Transl Oncol. 2021 Jul;14(7):101086. doi: 10.1016/j.tranon.2021.101086. Epub 2021 Apr 8. |
33839593 |
Burkett A, McElwee S, Margaroli C, Bajpai P, Elkholy A, Manne U, Wille K, Benson P. Positive Retrospective SARS-CoV-2 Testing in a Case of Acute Respiratory Distress Syndrome of Unknown Etiology. Case Rep Pulmonol. 2021 Aug 28;2021:5484239. doi: 10.1155/2021/5484239. eCollection 2021. |
34513107 |
Chandrashekar DS, Athar M, Manne U, Varambally S. Comparative transcriptome analyses reveal genes associated with SARS-CoV-2 infection of human lung epithelial cells.Sci Rep. 2021 Aug 10;11(1):16212. doi: 10.1038/s41598-021-95733-w |
34376762 |
Behring M, Ye Y, Elkholy A, Bajpai P, Agarwal S, Kim HG, Ojesina AI, Wiener HW, Manne U, Shrestha S, Vazquez AI. Immunophenotype-associated gene signature in ductal breast tumors varies by receptor subtype, but the expression of individual signature genes remains consistent. Cancer Med. 2021 Aug;10(16):5712-5720. doi: 10.1002/cam4.4095. Epub 2021 Jun 29. |
34189853 |
Robinson AD, Chakravarthi BVSK, Agarwal S, Chandrashekar DS, Davenport ML, Chen G, Manne U, Beer DG, Edmonds MD, Varambally S.Collagen modifying enzyme P4HA1 is overexpressed and plays a role in lung adenocarcinoma. Transl Oncol. 2021 Aug;14(8):101128. doi: 10.1016/j.tranon.2021.101128. Epub 2021 May 25. |
34049151 |
Memon RA, Granada CNP, Patel C, Manne U, Heslin MJ, Gbolahan OB, Harada S, Diffalha SA. Gastric Sclerosing Epithelioid Fibrosarcoma Harboring a Rare FUS-CREM Fusion. Int J Surg Pathol. 2021 Aug;29(5):565-570. doi: 10.1177/1066896920961174. Epub 2020 Sep 23. |
32964769 |
Shanmugam C, Behring M, Luthra V, Leal SM, Diffalha SA, Varambally S, Netto GJ, Manne U.Meta-Analysis of Robustness of COVID-19 Diagnostic Kits During Early Pandemic. MedRxiv. 2021 Jan 20:2021.01.16.21249937. doi: 10.1101/2021.01.16.21249937. |
33501458 |
Stokes Iii J, Vinayak S, Williams J, Malik S, Singh R, Manne U, Owonikoko TK, Mishra MK. Optimum health and inhibition of cancer progression by microbiome and resveratrol. Front Biosci (Landmark Ed). 2021 Jan 1;26:496-517. |
33049680 |
Espinoza I, Agarwal S, Reddy A, Shenoy V, Subramony C, Sakiyama M, Fair L, Poosarla T, Zhou X, Shannon Orr W, Lahr C, Bae S, Al Diffalha S, Manne U, Gomez CR. Expression of trefoil factor 3 is decreased in colorectal cancer. Oncol Rep. 2021 Jan;45(1):254-264. doi: 10.3892/or.2020.7829. |
33210724 |
Agarwal S, Behring M, Kim HG, Chandrashekar DS, Chakravarthi BVSK, Gupta N, Bajpai P, Elkholy A, Al Diffalha S, Datta PK, Heslin MJ, Varambally S, Manne U. TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status. Mol Oncol. 2020 Dec;14(12):3007-3029. doi: 10.1002/1878-0261.12821. |
33037736 |
Mishra NK, Niu M, Southekal S, Bajpai P, Elkholy A, Manne U, Guda C. Identification of Prognostic Markers in Cholangiocarcinoma Using Altered DNA Methylation and Gene Expression Profiles. Front Genet. 2020 Oct 20;11:522125. doi: 10.3389/fgene.2020.522125. |
33193605 |
Gibson JT, Orlandella RM, Turbitt WJ, Behring M, Manne U, Sorge RE, Norian LA. Obesity-Associated Myeloid-Derived Suppressor Cells Promote Apoptosis of Tumor-Infiltrating CD8 T Cells and Immunotherapy Resistance in Breast Cancer. Front Immunol. 2020 Oct 6;11:590794. doi: 10.3389/fimmu.2020.590794. |
33123173 |
Memon RA, Granada CNP, Patel C, Manne U, Heslin MJ, Gbolahan OB, Harada S, Diffalha SA. Gastric Sclerosing Epithelioid Fibrosarcoma Harboring a Rare FUS- CREM Fusion. Int J Surg Pathol. 2020 Sep 23:1066896920961174. doi: 10.1177/1066896920961174. |
32964769 |
Agarwal S, Chakravarthi BVSK, Kim HG, Gupta N, Hale K, Balasubramanya SAH, Oliver PG, Thomas DG, Eltoum IA, Buchsbaum DJ, Manne U, Varambally S. PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression. Transl Oncol. 2020 Jul;13(7):100776. doi: 10.1016/j.tranon.2020.100776. |
32422575 |
Davis M, Martini R, Newman L, Elemento O, White J, Verma A, Datta I, Adrianto I, Chen Y, Gardner K, Kim HG, Colomb WD, Eltoum IE, Frost AR, Grizzle WE, Sboner A, Manne U, Yates C.Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models in Admixed Race Populations Cancers (Basel). 2020 May 13;12(5):1220. doi: 10.3390/cancers12051220. |
32414099 |
Chandrashekar DS, Chakravarthi BVSK, Robinson AD, Anderson JC, Agarwal S, Balasubramanya SAH, Eich ML, Bajpai AK, Davuluri S, Guru MS, Guru AS, Naik G, Della Manna DL, Acharya KK, Carskadon S, Manne U, Crossman DK, Ferguson JE, Grizzle WE, Palanisamy N, Willey CD, Crowley MR, Netto GJ, Yang ES, Varambally S, Sonpavde G.Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression. Oncogene. 2020 May;39(20):4077-4091. doi: 10.1038/s41388-020-1275-7. |
32231273 |
Agarwal S, Chakravarthi BVSK, Behring M, Kim HG, Chandrashekar DS, Gupta N, Bajpai P, Elkholy A, Balasubramanya SAH, Hardy C, Diffalha SA, Varambally S, Manne U. PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer. Cancers (Basel). 2020 Mar 25;12(4). pii: E772. doi: 10.3390/cancers12040772. |
32218208 |
Agarwal S, Behring M, Kim HG, Bajpai P, Chakravarthi BVSK, Gupta N, Elkholy A, Al Diffalha S, Varambally S, Manne U. Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model. Transl Oncol. 2020 Mar 18;13(4):100754. doi: 10.1016/j.tranon.2020. |
32199274 |
Chandrashekar DS, Chakravarthi BVSK, Robinson AD, Anderson JC, Agarwal S, Balasubramanya SAH, Eich ML, Bajpai AK, Davuluri S, Guru MS, Guru AS, Naik G, Della Manna DL, Acharya KK, Carskadon S, Manne U, Crossman DK, Ferguson JE, Grizzle WE, Palanisamy N, Willey CD, Crowley MR, Netto GJ, Yang ES, Varambally S, Sonpavde G. Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression. Oncogene. 2020 Mar 30. doi: 10.1038/s41388-020-1275-7. |
32231273 |
Mittal K, Toss MS, Wei G, Kaur J, Choi DH, Melton BD, Osan RM, Miligy IM, Green AR, Janssen EAM, Søiland H, Gogineni K, Manne U, Rida P, Rakha EA, Aneja R. A Quantitative Centrosomal Amplification Score Predicts Local Recurrence of Ductal Carcinoma In Situ.Clin Cancer Res. 2020 Jan 14. doi: 10.1158/1078-0432.CCR-19-1272. |
31937618 |
Behring M, Hale K, Ozaydin B, Grizzle WE, Sodeke SO, Manne U. Inclusiveness and ethical considerations for observational, translational, and clinical cancer health disparity research. Cancer. 2019 Sep 10. doi: 10.1002/cncr.32495. |
31502259 |
Behring M, Vazquez AI, Cui X, Irvin MR, Ojesina AI, Agarwal S, Manne U, Shrestha S. Gain of function in somatic TP53 mutations is associated with immune-rich breast tumors and changes in tumor-associated macrophages. Mol Genet Genomic Med. 2019 Oct 22:e1001. |
31637877 |
Agarwal S, Behring M, Hale K, Al Diffalha S, Wang K, Manne U, Varambally S. MTHFD1L, A Folate Cycle Enzyme, Is Involved in Progression of Colorectal Cancer. Transl Oncol. 2019 Nov;12(11):1461-1467. |
31421459 |
Bhattarai S, Klimov S, Mittal K, Krishnamurti U, Li XB, Oprea-Ilies G, Wetherilt CS, Riaz A, Aleskandarany MA, Green AR, Ellis IO, Cantuaria G, Gupta M, Manne U, Agboola J, Baskovich B, Janssen EAM, Callagy G, Walsh EM, Mehta A, Dogra A, Shet T, Gajaria P, Traina T, Nggada HA, Omonisi A, Ahmed SA, Rakha EA, Rida P, Aneja R. Prognostic Role of Androgen Receptor in Triple Negative Breast Cancer: A Multi-Institutional Study. Cancers (Basel). 2019 Jul 17;11(7). |
31319547 |
Bedi D, Henderson HJ, Manne U, Samuel T. Induces PD-L1 and Immunomodulatory Cytokines in Colon Cancer Cells. Medicines (Basel). 2019 Apr 24;6(2). |
31022845 |
Hebert-Magee S, Yu H, Behring M, Jadhav T, Shanmugam C, Frost A, Eltoum IE, Varambally S, Manne U. The combined survival effect of codon 72 polymorphisms and p53 somatic mutations in breast cancer depends on race and molecular subtype. PLoS One. 2019;14(2):e0211734. |
30730944 |
Hasan S, Jacob R, Manne U, Paluri R. Advances in pancreatic cancer biomarkers Article. Oncology Reviews. 2019 (Feb); 13(1). |
31044028 |
Behring M, Shrestha S, Manne U, Cui X, Gonzalez-Reymundez A, Grueneberg A, Vazquez AI. Integrated landscape of copy number variation and RNA expression associated with nodal metastasis in invasive ductal breast carcinoma. Oncotarget. 2018;9(96):36836-36848. |
30627325 |
Chakravarthi BVSK, Chandrashekar DS, Hodigere Balasubramanya SA, Robinson AD, Carskadon S, Rao U, Gordetsky J, Manne U, Netto GJ, Sudarshan S, Palanisamy N, Varambally S. Wnt receptor Frizzled 8 is a target of ERG in prostate cancer. Prostate. 2018;78(16):1311-1320. |
30051493 |
Kouba E, Ford A, Brown CG, Yeh C, Siegal GP, Manne U, Eltoum IE. Detection of BRAF V600E Mutations With Next-Generation Sequencing in Infarcted Thyroid Carcinomas After Fine-Needle Aspiration. |
29868707 |
Kumar S, Gurshaney S, Adagunodo Y, Gage E, Qadri S, Sharma M, Malik S, Manne U, Singh UP, Singh R, Mishra MK. Hsp70 and gama-Semino protein as possible prognostic marker of prostate cancer. Front Biosci (Landmark Ed). 2018; 23:1987-2000. |
29772540 |
Kumar S, Singh R, Malik S, Manne U, Mishra M. Prostate cancer health disparities: An immuno-biological perspective. Cancer Lett. 2018;414:153-165. |
29154974 |
Jia X, Shanmugam C, Paluri RK, Jhala NC, Behring MP, Katkoori VR, Sugandha SP, Bae S, Samuel T, Manne U. Prognostic Value of Loss of Heterozygosity and Sub-Cellular Localization of SMAD4 Varies with Tumor Stage in Colorectal Cancer. Oncotarget, 2017; 8:20198-20212. |
28423626 |
Koo DH, Singh B, Jiang J, Friebe B, Gill BS, Chastain PD, Manne U, Tiwari HK, Singh KK. Single molecule mtDNA fiber FISH for analyzing numtogenesis. Anal Biochem. 2017, pii: S0003-2697(17)30131-8. |
28322800 |
Chakravarthi BVSK, Chandrashekar DS, Agarwal S, Balasubramanya SAH, Pathi SS, Goswami MT, Jing X, Wang R, Mehra R, Asangani IA, Chinnaiyan AM, Manne U, Sonpavde G, Netto GJ, Gordetsky J, Varambally S. miR-34a Regulates Expression of the Stathmin-1 Oncoprotein and Prostate Cancer Progression. Mol Cancer Res. 2017, DOI: 10.1158/1541-7786.MCR-17-0230. |
29025958 |
Kumar S, Stokes J III , Singh UP, Scissum-Gunn K, Manne U, Mishra M. Prolonged exposure of resveratrol induces reactive superoxide species-independent apoptosis in murine prostate cells. Tumor Biology, 2017; 1-20 |
29065794 |
Katkoori VR, Manne U, Chaturvedi L, Basson M, Haan P, Coffey D, Bumpers HL. Functional consequence of the p53 codon 72 polymorphism in colorectal cancer. Oncotarget, 2017, Aug 29;8(44):76574-76586. |
29100333 |
Chowdhury R, Gales D, Valenzuela P, Miller S, Yehualaeshet T, Manne U, Francia G, Samuel T. Bromoethylindole (BEI-9) redirects NF-κB signaling induced by camptothecin and TNFα to promote cell death in colon cancer cells. Apoptosis. 2017 Dec;22(12):1553-1563. |
29116428 |
Zhang W, Zhang B, Vu T, Yan G, Zhang B, Chen X, Manne U, Datta PK. Molecular characterization of pro-metastatic functions of ß4-integrin in colorectal cancer. Oncotarget, 2017, 27;8(54):92333-92345. |
29190919 |
Kaye S, Zeng Z, Sanders M, Chittur K, Koelle PM, Lindquist R, Manne U, Lin Y, Wei J. Label-Free Detection of DNA Hybridization with A Compact LSPR-based Fiber-Optic Sensor. Analyst, 2017, 142(11):1974-1981.DOI: 10.1039/C7AN00249A |
28504795 |
Kumar S, Stokes J III , Eroglu E, Scissum-Gunn K, Saldanha S, Singh U, Manne U, Ponnazhagan S, Mishra M. Resveratrol induces mitochondria-mediated, caspase-independent apoptosis in murine prostate cancer cells. Oncotarget, 2017; DOI: 10.18632/oncotarget.14947. |
28157696 |
Council LN, Shanmugam C, Suswam EA, Katkoori VR, Heslin MJ, Hanna A, Jhala NC, Varambally S, Manne U.Association between Hepatitis C Virus Infection, p53 Phenotypes, and Gene Variants of Adenomatous Polyposis Coli in Hepatocellular Carcinomas.J Dig Dis Hepatol. 2016;2016(5). pii: JDDH-121. |
28203651 |
Govindarajan R, Posey J, Chao CY, Lu R, Jadhav T, Javed AY, Javed A, Mahmoud FA, Osarogiagbon RU, Manne U. A comparison of 12-gene colon cancer assay gene expression in African American and Caucasian patients with stage II colon cancer.BMC Cancer. 2016;16:368. |
27316467 |
Kumar S, Stokes J 3rd, Singh UP, Scissum Gunn K, Acharya A, Manne U, Mishra M. Targeting Hsp70: A possible therapy for cancer.Cancer Lett. 2016;374(1):156-66. |
26898980 |
Krishna SR, Kaur S, Smith LM, Johansson SL, Jain M, Patel A, Gautam SK, Hollingsworth MA, Mandel U, Clausen H, Lo WC, Fan WL, Manne U, Batra SK. Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer. Cancer Lett. 2016. pii: S0304-3835(16)30070-2. |
26898938 |
Narayanan NK, Kunimasa K, Yamori Y, Mori M, Mori H, Nakamura K, Miller G, Manne U, Tiwari AK, Narayanan B. Antitumor activity of melinjo (Gnetum gnemon L.) seed extract in human and murine tumor models in vitro and in a colon-26 tumor-bearing mouse model in vivo.Cancer Med. 2015;4(11):1767-80. |
26408414 |
Katkoori VR, Basson MD, Bond VC, Manne U, Bumpers HL.Nef-M1, a peptide antagonist of CXCR4, inhibits tumor angiogenesis and epithelial‑to‑mesenchymal transition in colon and breast cancers.Oncotarget. 2015;6(29):27763-77. |
6318034 |
Fadlalla K, Elgendy R, Gilbreath E, Pondugula SR, Yehualaeshet T, Mansour M, Serbessa T, Manne U, Samuel T.3-(2-Bromoethyl)-indole inhibits the growth of cancer cells and NF-κB activation.Oncol Rep. 2015;34(1):495-503. |
26063116 |
Bumpers HL, Janagama DG, Manne U, Basson MD, Katkoori V.Nanomagnetic levitation three-dimensional cultures of breast and colorectal cancers.J Surg Res. 2015;194(2):319-26. |
25617973 |
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