Appointment Type |
Department |
Division |
Rank |
Primary |
Clinical Pathology |
Anatomic Pathology |
Professor |
Center |
Comprehensive Cancer Center |
Comprehensive Cancer Center |
Professor |
Center |
Minority Health & Research Center |
Minority Health & Research Center |
Professor |
Center |
Nutrition Sciences Research |
Nutrition Obesity Res Ctr (NORC) |
Professor |
Secondary |
Surgery - General Surgery |
Surgery - Gen Surg Gastrointestinal Section |
Professor |
|
Cancer Biology |
Integrative Biomedical Sciences |
Medical Scientist Training Program |
Molecular and Cellular Pathology Program |
Pathobiology and Molecular Medicine |
|
Publication |
PUBMEDID |
Kennedy RD, Bylesjo M, Kerr P, Davison T, Black JM, Kay EW, Holt RJ, Proutski V, Ahdesmaki M, Farztdinov V, Goffard N, Hey P, McDyer F, Mulligan K, Mussen J, O'Brien E, Oliver G, Walker SM, Mulligan JM, Wilson C, Winter A, O'Donoghue D, Mulcahy H, O'Sullivan J, Sheahan K, Hyland J, Dhir R, Bathe OF, Winqvist O, Manne U, Shanmugam C, Ramaswamy S, Leon EJ, Smith WI Jr, McDermott U, Wilson RH, Longley D, Marshall J, Cummins R, Sargent DJ, Johnston PG, Harkin DP.Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue. J Clin Oncol. 2011 Dec 10;29(35):4620-6. |
22067406 |
Grizzle WE, Srivastava S, Manne U. Translational pathology of neoplasia. Cancer Biomark. 2010;9(1-6):7-20 (Review). |
22112467 |
Manne U, Shanmugam C, Katkoori VR, Bumpers HL, Grizzle WE.Development and progression of colorectal neoplasia (Review).Cancer Biomark., 2011;9(1-6):235-65. |
22112479 |
Bovell L, Shanmugam C, Katkoori VR, Zhang B, Vogtmann E, Grizzle WE, Manne U.miRNAs are stable in colorectal cancer archival tissue blocks.Front Biosci (Elite Ed). 2012 Jan 1;4:1937-40. |
22202009 |
Samuel T, Fadlalla K, Mosley L, Katkoori V, Turner T, Manne U.Dual-mode Interaction between Quercetin and DNA-damaging Drugs in Cancer Cells.Anticancer Res. 2012 Jan;32(1):61-71. |
22213289 |
Katkoori VR, Shanmugam C, Jia X, Vitta SP, Sthanam M, et al. () Prognostic Significance and Gene Expression Profiles of p53 Mutations in Microsatellite-Stable Stage III Colorectal Adenocarcinomas. PLoS ONE, 2012;7(1): e30020. doi:10.1371/journal.pone.0030020 |
22276141 |
Tuupanen S, Yan J, Turunen M, Gylfe AE, Kaasinen E, Li L, Eng C, Culver DA, Kalady MF, Pennison MJ, Pasche B, Manne U, de la Chapelle A, Hampel H, Henderson BE, Le Marchand L, Hautaniemi S, Askhtorab H, Smoot D, Sandler RS, Keku T, Kupfer SS, Ellis NA, Haiman CA, Taipale J, Aaltonen LA.Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: the role of rs67491583. Cancer Genet. 2012 Jan-Feb;205(1-2):25-33. |
22429595 |
Bowman E, Oprea G, Okoli J, Gundry K, Rizzo M, Gabram-Mendola S, Manne U, Smith G, Pambuccian S, Bumpers HL. Pseudoangiomatous stromal hyperplasia (PASH) of the breast: a series of 24 patients.Breast J. 2012 May-Jun;18(3):242-7. |
22583194 |
Katkoori VR, Suerez-Curvo C, Shanmugam C, Bumpers, H, Posey J, Grizzle, WE, Manne U. Bax expression is a prognostic and predictive marker in colorectal cancer. J. Gastrointest Oncol, 2010;1:76-89. |
22811811 |
Katkoori VR, Manne K, Vital-Reyes VS, Rodríguez-Burford C, Shanmugam C, Sthanam M, Manne U, Chatla C, Abdulkadir SA, Grizzle WE.Selective COX-2 inhibitor (celecoxib) decreases cellular growth in prostate cancer cell lines independent of p53. Biotech Histochem. 2013 Jan;88(1):38-46. |
23167625 |
McNally L, Manne U, Grizzle WE.Post-transcriptional processing of genetic information and its relation to cancer.Biotech Histochem. 2013;88(7):365-72. |
23286224 |
Vogtmann E, Shanmugam C, Katkoori VR, Waterbor J, Manne U.Socioeconomic status, p53 abnormalities, and colorectal cancer.J Gastrointest Oncol. 2013 Mar;4(1):40-4. |
23450636 |
Bovell LC, Putcha BD, Samuel T, Manne U.Clinical implications of microRNAs in cancer.Biotech Histochem. 2013 Oct;88(7):388-96 |
23647010 |
Bovell LC, Shanmugam C, Putcha BD, Katkoori VR, Zhang B, Bae S, Singh KP, Grizzle WE, Manne U.The Prognostic Value of MicroRNAs Varies with Patient Race/Ethnicity and Stage of Colorectal Cancer.Clin Cancer Res. 2013 Jul 15;19(14):3955-65. |
23719259 |
Gales D, Clark C, Manne U, Samuel T.The Chemokine CXCL8 in Carcinogenesis and Drug Response. ISRN Oncol. 2013;2013:859154 (Review). |
24224100 |
Samuel T, Fadlalla K, Gales DN, Putcha BD, Manne U.Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugs.BMC Cancer. 2014 Aug 18;14:599. |
25134433 |
Tabatabai MA, Kengwoung-Keumo JJ, Eby WM, Bae S, Guemmegne JT, Manne U, Fouad M, Partridge EE, Singh KP.Disparities in cervical cancer mortality rates as determined by the longitudinal hyperbolastic mixed-effects type II model.PLoS One. 2014;9(9):e107242. |
25226583 |
Karthikeyan C, Lee C, Moore J, Mittal R, Suswam EA, Abbott KL, Pondugula SR, Manne U, Narayanan NK, Trivedi P, Tiwari AK. IND-2, a pyrimido[1″,2″:1,5]pyrazolo[3,4-b]quinoline derivative, circumvents multi-drug resistance and causes apoptosis in colon cancer cells.Bioorg Med Chem. 2015;23(3):602-11. |
25537531 |
Bumpers HL, Janagama DG, Manne U, Basson MD, Katkoori V.Nanomagnetic levitation three-dimensional cultures of breast and colorectal cancers.J Surg Res. 2015;194(2):319-26. |
25617973 |
Fadlalla K, Elgendy R, Gilbreath E, Pondugula SR, Yehualaeshet T, Mansour M, Serbessa T, Manne U, Samuel T.3-(2-Bromoethyl)-indole inhibits the growth of cancer cells and NF-κB activation.Oncol Rep. 2015;34(1):495-503. |
26063116 |
Putcha BD, Jia X, Katkoori VR, Salih C, Shanmugam C, Jadhav T, Bovell LC, Behring MP, Callens T, Messiaen L, Bae S, Grizzle WE, Singh KP, Manne U.Clinical Implications of Rabphillin-3A-Like Gene Alterations in Breast Cancer.PLoS One. 2015 12;10(6):e0129216. |
26070152 |
Tabatabai MA, Li H, Eby WM, Kengwoung-Keumo JJ, Manne U, Bae S, Fouad M, Singh KP.Robust Logistic and Probit Methods for Binary and Multinomial Regression.J Biom Biostat. 2014;5(4). pii: 202. |
26078914 |
Tabatabai MA, Kengwoung-Keumo JJ, Eby WM, Bae S, Manne U, Fouad M, Singh KP.A New Robust Method for Nonlinear Regression. J Biom Biostat. 2014;5(5):211 |
26185732 |
Narayanan NK, Kunimasa K, Yamori Y, Mori M, Mori H, Nakamura K, Miller G, Manne U, Tiwari AK, Narayanan B. Antitumor activity of melinjo (Gnetum gnemon L.) seed extract in human and murine tumor models in vitro and in a colon-26 tumor-bearing mouse model in vivo.Cancer Med. 2015;4(11):1767-80. |
26408414 |
Krishna SR, Kaur S, Smith LM, Johansson SL, Jain M, Patel A, Gautam SK, Hollingsworth MA, Mandel U, Clausen H, Lo WC, Fan WL, Manne U, Batra SK. Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer. Cancer Lett. 2016. pii: S0304-3835(16)30070-2. |
26898938 |
Govindarajan R, Posey J, Chao CY, Lu R, Jadhav T, Javed AY, Javed A, Mahmoud FA, Osarogiagbon RU, Manne U. A comparison of 12-gene colon cancer assay gene expression in African American and Caucasian patients with stage II colon cancer.BMC Cancer. 2016;16:368. |
27316467 |
Kumar S, Stokes J III , Eroglu E, Scissum-Gunn K, Saldanha S, Singh U, Manne U, Ponnazhagan S, Mishra M. Resveratrol induces mitochondria-mediated, caspase-independent apoptosis in murine prostate cancer cells. Oncotarget, 2017; DOI: 10.18632/oncotarget.14947. |
28157696 |
Council LN, Shanmugam C, Suswam EA, Katkoori VR, Heslin MJ, Hanna A, Jhala NC, Varambally S, Manne U.Association between Hepatitis C Virus Infection, p53 Phenotypes, and Gene Variants of Adenomatous Polyposis Coli in Hepatocellular Carcinomas.J Dig Dis Hepatol. 2016;2016(5). pii: JDDH-121. |
28203651 |
Koo DH, Singh B, Jiang J, Friebe B, Gill BS, Chastain PD, Manne U, Tiwari HK, Singh KK. Single molecule mtDNA fiber FISH for analyzing numtogenesis. Anal Biochem. 2017, pii: S0003-2697(17)30131-8. |
28322800 |
Jia X, Shanmugam C, Paluri RK, Jhala NC, Behring MP, Katkoori VR, Sugandha SP, Bae S, Samuel T, Manne U. Prognostic Value of Loss of Heterozygosity and Sub-Cellular Localization of SMAD4 Varies with Tumor Stage in Colorectal Cancer. Oncotarget, 2017; 8:20198-20212. |
28423626 |
Kaye S, Zeng Z, Sanders M, Chittur K, Koelle PM, Lindquist R, Manne U, Lin Y, Wei J. Label-Free Detection of DNA Hybridization with A Compact LSPR-based Fiber-Optic Sensor. Analyst, 2017, 142(11):1974-1981.DOI: 10.1039/C7AN00249A |
28504795 |
Chakravarthi BVSK, Chandrashekar DS, Agarwal S, Balasubramanya SAH, Pathi SS, Goswami MT, Jing X, Wang R, Mehra R, Asangani IA, Chinnaiyan AM, Manne U, Sonpavde G, Netto GJ, Gordetsky J, Varambally S. miR-34a Regulates Expression of the Stathmin-1 Oncoprotein and Prostate Cancer Progression. Mol Cancer Res. 2017, DOI: 10.1158/1541-7786.MCR-17-0230. |
29025958 |
Kumar S, Stokes J III , Singh UP, Scissum-Gunn K, Manne U, Mishra M. Prolonged exposure of resveratrol induces reactive superoxide species-independent apoptosis in murine prostate cells. Tumor Biology, 2017; 1-20 |
29065794 |
Katkoori VR, Manne U, Chaturvedi L, Basson M, Haan P, Coffey D, Bumpers HL. Functional consequence of the p53 codon 72 polymorphism in colorectal cancer. Oncotarget, 2017, Aug 29;8(44):76574-76586. |
29100333 |
Chowdhury R, Gales D, Valenzuela P, Miller S, Yehualaeshet T, Manne U, Francia G, Samuel T. Bromoethylindole (BEI-9) redirects NF-κB signaling induced by camptothecin and TNFα to promote cell death in colon cancer cells. Apoptosis. 2017 Dec;22(12):1553-1563. |
29116428 |
Kumar S, Singh R, Malik S, Manne U, Mishra M. Prostate cancer health disparities: An immuno-biological perspective. Cancer Lett. 2018;414:153-165. |
29154974 |
Zhang W, Zhang B, Vu T, Yan G, Zhang B, Chen X, Manne U, Datta PK. Molecular characterization of pro-metastatic functions of ß4-integrin in colorectal cancer. Oncotarget, 2017, 27;8(54):92333-92345. |
29190919 |
Kumar S, Gurshaney S, Adagunodo Y, Gage E, Qadri S, Sharma M, Malik S, Manne U, Singh UP, Singh R, Mishra MK. Hsp70 and gama-Semino protein as possible prognostic marker of prostate cancer. Front Biosci (Landmark Ed). 2018; 23:1987-2000. |
29772540 |
Kouba E, Ford A, Brown CG, Yeh C, Siegal GP, Manne U, Eltoum IE. Detection of BRAF V600E Mutations With Next-Generation Sequencing in Infarcted Thyroid Carcinomas After Fine-Needle Aspiration. |
29868707 |
Chakravarthi BVSK, Chandrashekar DS, Hodigere Balasubramanya SA, Robinson AD, Carskadon S, Rao U, Gordetsky J, Manne U, Netto GJ, Sudarshan S, Palanisamy N, Varambally S. Wnt receptor Frizzled 8 is a target of ERG in prostate cancer. Prostate. 2018;78(16):1311-1320. |
30051493 |
Behring M, Shrestha S, Manne U, Cui X, Gonzalez-Reymundez A, Grueneberg A, Vazquez AI. Integrated landscape of copy number variation and RNA expression associated with nodal metastasis in invasive ductal breast carcinoma. Oncotarget. 2018;9(96):36836-36848. |
30627325 |
Hebert-Magee S, Yu H, Behring M, Jadhav T, Shanmugam C, Frost A, Eltoum IE, Varambally S, Manne U. The combined survival effect of codon 72 polymorphisms and p53 somatic mutations in breast cancer depends on race and molecular subtype. PLoS One. 2019;14(2):e0211734. |
30730944 |
Bedi D, Henderson HJ, Manne U, Samuel T. Induces PD-L1 and Immunomodulatory Cytokines in Colon Cancer Cells. Medicines (Basel). 2019 Apr 24;6(2). |
31022845 |
Hasan S, Jacob R, Manne U, Paluri R. Advances in pancreatic cancer biomarkers Article. Oncology Reviews. 2019 (Feb); 13(1). |
31044028 |
Bhattarai S, Klimov S, Mittal K, Krishnamurti U, Li XB, Oprea-Ilies G, Wetherilt CS, Riaz A, Aleskandarany MA, Green AR, Ellis IO, Cantuaria G, Gupta M, Manne U, Agboola J, Baskovich B, Janssen EAM, Callagy G, Walsh EM, Mehta A, Dogra A, Shet T, Gajaria P, Traina T, Nggada HA, Omonisi A, Ahmed SA, Rakha EA, Rida P, Aneja R. Prognostic Role of Androgen Receptor in Triple Negative Breast Cancer: A Multi-Institutional Study. Cancers (Basel). 2019 Jul 17;11(7). |
31319547 |
Behring M, Hale K, Ozaydin B, Grizzle WE, Sodeke SO, Manne U. Inclusiveness and ethical considerations for observational, translational, and clinical cancer health disparity research. Cancer. 2019 Sep 10. doi: 10.1002/cncr.32495. |
31502259 |
Behring M, Vazquez AI, Cui X, Irvin MR, Ojesina AI, Agarwal S, Manne U, Shrestha S. Gain of function in somatic TP53 mutations is associated with immune-rich breast tumors and changes in tumor-associated macrophages. Mol Genet Genomic Med. 2019 Oct 22:e1001. |
31637877 |
Mittal K, Toss MS, Wei G, Kaur J, Choi DH, Melton BD, Osan RM, Miligy IM, Green AR, Janssen EAM, Søiland H, Gogineni K, Manne U, Rida P, Rakha EA, Aneja R. A Quantitative Centrosomal Amplification Score Predicts Local Recurrence of Ductal Carcinoma In Situ.Clin Cancer Res. 2020 Jan 14. doi: 10.1158/1078-0432.CCR-19-1272. |
31937618 |
Agarwal S, Behring M, Kim HG, Bajpai P, Chakravarthi BVSK, Gupta N, Elkholy A, Al Diffalha S, Varambally S, Manne U. Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model. Transl Oncol. 2020 Mar 18;13(4):100754. doi: 10.1016/j.tranon.2020. |
32199274 |
Agarwal S, Chakravarthi BVSK, Behring M, Kim HG, Chandrashekar DS, Gupta N, Bajpai P, Elkholy A, Balasubramanya SAH, Hardy C, Diffalha SA, Varambally S, Manne U. PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer. Cancers (Basel). 2020 Mar 25;12(4). pii: E772. doi: 10.3390/cancers12040772. |
32218208 |
|
|